No definition available.
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
220 |
4. Check minimum number of eventsNone |
220 |
5. Include endpointsNone |
220 |
6. Filter based on genotype QC (FinnGen only) |
118 |
Control definitions (FinnGen only)
Controls for this endpoint are individuals that are not cases.
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF8
- Parent code in ICD-10
- C81-C96
- Name in latin
- Leuc(h)aemia monocytica
Similar endpoints
↥List of similar endpoints to
Monocytic leukaemia
based on the number of shared cases.
Similar with more cases:
- Primary_lymphoid and hematopoietic malignant neoplasms
- Liquid cancers
- Liquid cancers, including Hilmo
- Malignant neoplasm
- Malignant neoplasm
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
This endpoint is excluded (different definition than used in FinnGen).
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 118 | 51 | 67 |
| Unadjusted period prevalence (%) | 0.03 | 0.02 | 0.03 |
| Median age at first event (years) | 69.24 | 66.42 | 71.39 |
-FinnGen-
Age distribution of first events
-FinnGen-
Year distribution of first events
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 125
- Matched controls
- 1250
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
43.0
102.5
77
45
XW000
NOMESCO Finland
Bone marrow biopsy
29.4
75.3
60
38
C93.1
ICD-10 Finland
Chronic myelomonocytic leukaemia
+∞
72.0
62
*
9945/3-C42.1
ICD-O-3
Chronic myelomonocytic leukemia, NOS, of bone marrow
+∞
42.1
38
*
D46.7
ICD-10 Finland
Other myelodysplastic syndromes
150.5
40.6
41
*
C93.0
ICD-10 Finland
Acute monoblastic/monocytic leukaemia
+∞
39.7
36
*
WW500
NOMESCO Finland
Blood transfusion
9.9
24.1
32
42
C92.0
ICD-10 Finland
Acute myeloblastic leukaemia [AML]
83.3
19.4
21
*
M04AA01
ATC
allopurinol; systemic
5.6
18.8
50
134
Z51.5
ICD-10 Finland
Palliative care
5.9
17.1
38
86
A04AA01
ATC
ondansetron; systemic, rectal
6.4
16.8
33
66
D64.9
ICD-10 Finland
Anaemia, unspecified
5.3
16.3
43
113
JN3AE
NOMESCO Finland
Abdominal ultrasound examination
5.0
15.5
44
122
A49.9
ICD-10 Finland
Bacterial infection, unspecified
5.1
15.5
43
117
L01XX05
ATC
hydroxycarbamide; oral
36.9
15.3
19
6
C93.9
ICD-10 Finland
Monocytic leukaemia, unspecified
+∞
13.8
13
*
R50.9
ICD-10 Finland
Fever, unspecified
4.3
12.4
43
137
B03XA02
ATC
darbepoetin alfa; parenteral
19.4
11.6
17
10
D46.9
ICD-10 Finland
Myelodysplastic syndrome, unspecified
48.0
11.1
13
*
D69.6
ICD-10 Finland
Thrombocytopenia, unspecified
14.8
11.1
18
14
A05AA02
ATC
ursodeoxycholic acid; oral
32.9
9.6
12
*
C92.1
ICD-10 Finland
Chronic myeloid leukaemia [CML], BCR/ABL-positive
53.9
8.8
10
*
L03AA02
ATC
filgrastim; parenteral
8.6
8.5
18
24
9860/3-C42.1
ICD-O-3
Myeloid leukemia, NOS, of bone marrow
+∞
8.4
8
*
TPH20
NOMESCO Finland
Insertion of central venous catheter through subclavian or brachiocephalic vein
9.0
7.9
16
20
WW200
NOMESCO Finland
Immunization
11.1
7.8
14
14
127
Kela drug reimbursment
Transplant complication
19.9
7.7
11
6
9891/3-C42.1
ICD-O-3
Acute monocytic leukemia of bone marrow
+∞
7.4
7
*
9989/3-C42.1
ICD-O-3
Myelodysplastic syndrome, NOS, of bone marrow
42.4
6.8
8
*
9861/3-C42.1
ICD-O-3
Acute myeloid leukemia, NOS, of bone marrow
42.4
6.8
8
*
TNE25
NOMESCO Finland
Drill biopsy of bone marrow, pelvis
13.2
6.7
11
9
TPH15
NOMESCO Finland
Insertion of central venous catheter through external or internal jugular vein
4.5
6.6
17
42
J05AB11
ATC
valaciclovir; oral
3.1
6.5
33
130
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
4.3
6.5
18
47
L04AA01
ATC
[U] ciclosporin
73.4
6.5
7
*
Z94.8
ICD-10 Finland
Other transplanted organ and tissue status
28.2
6.3
8
*
G93.0
ICD-10 Finland
Cerebral cysts
+∞
6.3
6
*
WW302
NOMESCO Finland
Allogenic transfer of stem cells from relative
+∞
6.3
6
*
A41.9
ICD-10 Finland
Sepsis, unspecified
6.0
6.1
16
30
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
36
37
13.26
32.85
4.9
2.2
—
—
—
0
0
21
40
6.11
11.02
2.4
2.0
91.48
88.53
%
0.24
21
40
22
47
5.47
10.22
2.8
1.6
—
—
—
0
0
51
207
3.47
10.09
6.7
3.3
0.81
0.80
mmol/l
0.27
51
194
21
46
5.29
9.47
2.7
1.6
—
—
—
0
0
12
10
13.11
7.25
2.3
2.6
—
—
—
0
0
12
10
13.11
7.25
2.3
2.6
—
—
—
0
0
17
29
6.61
6.90
3.0
1.8
—
—
—
0
0
11
10
11.92
6.43
4.0
2.3
—
—
—
0
0
18
48
4.21
6.35
3.1
2.7
5.61
2.82
ratio
0.28
11
24
47
231
2.66
6.15
4.1
2.0
—
—
—
0
0
52
280
2.47
5.53
15.1
2.6
—
—
—
0
0
38
176
2.67
5.52
3.0
1.9
—
—
—
0
0
11
14
8.49
5.47
20.1
4.9
1.18
0.86
%
0.29
11
14
21
70
3.40
5.40
1.8
1.4
—
—
—
0
0
16
36
4.94
5.28
1.4
1.4
—
—
—
0
0
16
36
4.94
5.28
2.8
2.2
168.44
223.64
%
1.55
16
36
16
45
3.93
5.24
1.7
1.3
—
—
—
0
0
5
0
+∞
5.24
1.0
0.0
—
—
—
0
0
8
6
14.11
5.15
4.8
2.3
—
—
—
0
0
8
6
14.11
5.15
4.8
2.3
—
—
—
0
0
8
6
14.11
5.15
4.8
2.3
—
—
—
0
0
8
6
14.11
5.15
4.8
2.2
—
—
—
0
0
8
6
14.11
5.15
4.8
2.3
—
—
—
0
0
8
6
14.11
5.15
4.8
2.2
—
—
—
0
0
8
6
14.11
5.15
4.8
2.2
—
—
—
0
0
36
169
2.59
5.05
3.0
2.1
—
—
—
0
0
18
57
3.52
4.99
3.6
1.4
4.01
4.37
g/l
0.85
18
50
18
57
3.52
4.99
3.6
1.4
6.83
7.64
g/l
0.72
18
50
18
57
3.52
4.99
3.6
1.4
3.63
4.18
g/l
0.41
18
50
11
17
6.98
4.89
3.8
1.9
—
—
—
0
0
11
17
6.98
4.89
3.8
1.9
—
—
—
0
0
11
17
6.98
4.89
3.8
1.9
—
—
—
0
0
17
53
3.56
4.82
3.7
1.4
3.28
3.08
g/l
0.27
17
46
24
94
2.92
4.72
2.8
1.6
—
—
—
0
0
13
27
5.25
4.65
1.8
1.3
—
—
—
0
0
15
44
3.74
4.63
4.1
1.5
0.00
0.00
g/l
-0.00
15
37
10
15
7.14
4.56
1.6
1.3
—
—
—
0
0
79
540
2.26
4.56
16.1
2.9
—
—
estimate
—
0
0
18
62
3.22
4.38
2.4
1.9
1.86
5.53
ug/l
0.38
18
56
8
9
9.40
4.34
2.3
3.4
—
—
—
0
0
16
52
3.38
4.26
3.9
1.4
10.58
10.39
g/l
0.05
16
44
15
49
3.34
3.96
4.1
1.6
0.06
0.32
g/l
0.59
15
40
19
72
2.93
3.94
3.1
1.8
—
—
—
0
0
8
11
7.68
3.92
2.0
1.3
—
—
—
0
0
10
19
5.62
3.92
4.2
1.9
—
—
—
0
0
14
44
3.46
3.91
1.3
1.6
—
—
—
0
0
29
144
2.32
3.52
4.6
4.7
1.37
2.07
mmol/l
0.25
23
114
9
18
5.30
3.44
4.4
2.0
—
—
—
0
0
7
11
6.66
3.23
3.3
2.2
—
—
—
0
0
7
11
6.66
3.23
3.3
2.2
—
—
—
0
0
7
11
6.66
3.23
3.3
2.2
—
—
—
0
0
7
11
6.66
3.23
3.3
2.2
—
—
—
0
0
12
35
3.68
3.21
1.3
1.6
—
—
—
0
0
10
25
4.25
3.16
1.1
1.2
—
—
—
0
0
82
616
1.96
3.15
16.6
7.6
1.19
1.20
mmol/l
0.71
74
525
19
82
2.55
3.09
4.1
5.1
24.39
24.12
mmol/l
0.08
19
82
9
21
4.53
3.06
1.2
1.5
—
—
—
0
0
10
26
4.09
3.05
1.6
1.5
—
—
—
0
0
5
5
10.34
3.00
2.0
1.4
1002.40
1014.40
u/ml
—
5
5
11
32
3.67
2.98
2.6
1.5
—
—
—
0
0
6
9
6.93
2.90
1.3
1.2
—
—
—
0
0
12
39
3.29
2.86
7.2
1.3
0.25
0.22
g/l
0.50
12
39
64
454
1.84
2.83
6.3
3.5
—
—
—
0
0
33
188
2.03
2.82
4.7
3.3
1.56
1.94
e6/l
0.15
19
106
12
40
3.21
2.78
7.3
1.3
1.31
1.16
g/l
1.09
12
40
12
40
3.21
2.78
1.2
1.6
—
—
—
0
0
10
29
3.66
2.76
1.4
1.6
—
—
—
0
0
73
543
1.83
2.73
14.8
6.7
1.19
1.20
mmol/l
0.92
73
492
11
36
3.25
2.64
1.4
1.4
0.09
0.03
iu/ml
—
6
7
6
11
5.67
2.57
1.0
1.1
—
—
—
0
0
5
7
7.38
2.57
1.6
2.1
—
—
—
0
0
35
210
1.93
2.57
4.3
3.1
3.73
0.97
e6/l
0.59
22
125
9
26
3.65
2.53
1.9
1.2
—
—
—
0
0
6
12
5.19
2.43
3.7
2.1
—
—
—
0
0
6
12
5.19
2.43
3.7
2.1
—
—
—
0
0
17
80
2.30
2.31
7.5
3.1
1.69
1.83
mmol/l
0.03
12
67
9
29
3.26
2.27
1.9
1.4
—
—
—
0
0
9
29
3.26
2.27
1.7
1.2
—
—
—
0
0
23
124
2.05
2.26
3.7
4.4
4.01
4.27
kpa
0.42
23
119
9
30
3.15
2.19
1.8
1.4
—
—
—
0
0
9
30
3.15
2.19
1.8
1.4
—
—
—
0
0
11
43
2.71
2.14
6.7
2.0
—
—
—
0
0
6
16
3.88
1.96
1.0
1.6
—
—
—
0
0
13
60
2.30
1.85
5.6
5.4
1.39
1.52
%
0.46
13
53
7
23
3.16
1.83
1.4
1.6
—
—
—
0
0
38
262
1.65
1.70
1.5
1.9
509.79
440.33
pmol/l
0.61
33
217
7
25
2.90
1.67
1.1
1.8
—
—
—
0
0
7
26
2.79
1.60
6.1
5.5
39.43
34.32
mg/l
—
7
20
7
26
2.79
1.60
1.1
1.2
—
—
—
0
0
84
706
1.58
1.57
9.3
5.6
6.79
6.87
mmol/l
0.16
84
675
89
996
0.63
1.45
4.9
5.3
1.21
1.44
mmol/l
3.93
81
890
9
40
2.34
1.43
3.7
1.8
—
—
—
0
0
9
40
2.34
1.43
1.6
1.4
—
—
—
0
0
72
596
1.49
1.36
6.4
4.2
0.00
0.00
estimate
-0.00
19
129
51
394
1.50
1.36
3.9
3.2
49.31
33.52
u/l
0.40
51
372
30
206
1.60
1.34
8.1
7.2
104.57
104.06
mmol/l
0.23
30
206
93
1026
0.63
1.32
5.7
6.2
2.39
2.52
mmol/l
0.59
85
924
47
360
1.49
1.29
5.2
3.2
0.53
0.46
e6/l
0.13
40
280
86
962
0.66
1.27
4.8
4.5
1.42
1.27
mmol/l
0.97
78
857
13
71
1.93
1.25
2.0
4.8
0.68
0.65
%
0.13
13
71
72
603
1.46
1.24
6.5
4.3
0.05
0.00
estimate
0.48
21
134
11
57
2.02
1.21
3.8
3.1
—
—
—
0
0
61
499
1.43
1.17
5.1
4.4
36.53
44.18
ng/l
0.26
46
394
91
1000
0.67
1.12
5.2
5.5
4.10
4.40
mmol/l
1.53
84
903
13
74
1.84
1.11
2.0
4.7
2.05
1.14
%
0.73
13
74
72
611
1.42
1.11
6.5
4.3
0.00
0.03
estimate
0.50
20
122
5
22
2.32
1.04
2.6
4.4
—
—
—
0
0
6
30
2.05
0.88
1.0
1.3
—
—
—
0
0
19
131
1.53
0.84
5.9
3.7
—
—
—
0
0
24
175
1.46
0.83
5.4
7.1
1.79
1.12
mmol/l
0.30
17
147
30
229
1.41
0.81
1.2
1.3
0.97
1.80
u/ml
—
10
67
62
536
1.31
0.75
3.3
2.2
82.42
93.49
pmol/l
1.36
42
277
61
531
1.29
0.69
3.8
2.9
—
—
—
0
0
8
50
1.64
0.63
12.9
3.9
4.40
4.40
pmol/l
—
8
45
93
992
0.76
0.62
42.8
19.4
69.02
75.40
ml/min/173m2
1.50
88
926
22
167
1.39
0.62
1.5
1.3
6.30
12.50
u/ml
—
6
53
95
1009
0.76
0.60
6.3
5.7
6.40
6.10
mmol/l
0.74
89
906
0
22
0.00
0.60
0.0
1.6
—
15.95
—
0
22
33
271
1.30
0.57
7.7
4.8
1.02
1.02
kg/l
0.02
28
178
42
368
1.21
0.41
7.8
4.4
0.06
0.00
estimate
0.48
16
119
7
102
0.67
0.41
1.6
1.4
—
—
—
0
0
0
15
0.00
0.41
0.0
1.5
—
1.02
—
0
8
0
15
0.00
0.41
0.0
1.5
—
0.99
—
0
8
0
15
0.00
0.41
0.0
1.5
—
1.02
—
0
8
55
495
1.20
0.41
2.9
2.6
77.76
78.58
nmol/l
0.09
55
428
0
17
0.00
0.41
0.0
1.6
—
62.61
—
0
12
0
18
0.00
0.40
0.0
1.5
—
5.61
—
0
13
84
787
1.21
0.40
6.1
4.4
14.93
14.97
pmol/l
0.04
79
697
19
152
1.29
0.40
1.5
1.6
—
—
—
0
0
93
974
0.82
0.37
6.6
7.3
39.82
40.48
mmol/mol
0.25
87
896
52
471
1.18
0.35
7.4
4.3
0.19
0.00
estimate
0.48
16
110
38
339
1.17
0.30
6.2
3.7
0.25
0.00
estimate
0.47
12
109
13
107
1.24
0.22
2.5
1.7
1.72
1.63
%
0.20
13
88
5
41
1.23
0.22
1.2
1.2
—
—
—
0
0
5
41
1.23
0.22
1.2
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.1
—
—
—
0
0
6
50
1.21
0.20
1.5
1.3
—
—
—
0
0
93
954
0.90
0.15
7.4
5.3
2.07
2.00
mu/l
0.20
88
851
102
1039
0.90
0.12
57.2
19.4
30.50
26.09
mg/l
0.77
93
898
13
115
1.15
0.11
1.9
1.3
—
—
—
0
0
37
361
1.04
0.02
4.3
5.3
25.06
22.19
%
0.38
18
182
43
422
1.03
0.02
5.1
4.1
34.43
10.11
mg/mmol
1.11
31
263
13
136
0.95
0.00
12.8
8.9
—
—
—
0
0
46
466
0.98
0.00
4.6
6.1
1.84
2.78
ug/l
0.67
41
412
85
849
1.00
0.00
66.7
24.9
15.57
13.93
%
7.08
85
839
11
112
0.98
0.00
1.7
2.6
32.67
29.89
u/l
—
6
95
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.9
—
10.61
—
0
7
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
96.60
—
0
5
0
5
0.00
-0.00
0.0
1.6
—
6.82
—
0
5
5
58
0.86
-0.00
1.0
3.6
13.00
197.24
u/ml
—
5
49
0
7
0.00
-0.00
0.0
3.9
—
4.61
—
0
7
0
7
0.00
-0.00
0.0
1.9
—
—
—
0
0
0
7
0.00
-0.00
0.0
3.9
—
10.14
—
0
7
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
3.5
—
77.00
—
0
6
(40770918) von Willebrand factor (vWf).activity actual/normal in Platelet poor plasma by Immunoassay
0
5
0.00
-0.00
0.0
1.0
—
100.00
—
0
5
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥This endpoint is excluded (different definition than used in FinnGen).
Relationships between endpoints
↥Index endpoint: C3_MONOCYTIC_LEUKAEMIA – Monocytic leukaemia
GWS hits: -
This endpoint is excluded (different definition than used in FinnGen).