No definition available.
Fractures involving multiple body regions
ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters: 2 out of 7 registries used, show all original rules. |
91 |
4. Check minimum number of eventsNone |
91 |
5. Include endpointsNone |
91 |
6. Filter based on genotype QC (FinnGen only) |
81 |
Control definitions (FinnGen only)
- Control exclude
- ST19_INJURI_INVOLVI_MULTIPLE_BODY_REGIONS
Extra metadata
- Level in the ICD hierarchy
- 3
- First used in FinnGen datafreeze
- DF4
- Parent code in ICD-10
- T0[0-7]
- Name in latin
- Fracturae regionum multarum corporis
Similar endpoints
↥List of similar endpoints to
Fractures involving multiple body regions
based on the number of shared cases.
Similar with more cases:
- Injuries involving multiple body regions
- Accidents
- External causes of morbidity and mortality
- Injury, poisoning and certain other consequences of external causes
- Any operation in hilmo
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 824 | 329 | 486 |
| Only index persons | 693 | 273 | 420 |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.01 | 0.01 | 0.01 |
| Only index persons | 0.01 | 0.01 | 0.02 |
| Median age at first event (years) | |||
| Whole population | 53.75 | 63.34 | 46.96 |
| Only index persons | 52.08 | 60.94 | 46.32 |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 81 | 29 | 52 |
| Unadjusted period prevalence (%) | 0.02 | 0.01 | 0.02 |
| Median age at first event (years) | 55.13 | 63.35 | 50.55 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 84
- Matched controls
- 840
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
T02.1
ICD-10 Finland
Fractures involving thorax with lower back and pelvis
+∞
25.3
23
*
X59
ICD-10 Finland
Exposure to unspecified factor
6.2
15.8
42
116
T02.9
ICD-10 Finland
Multiple fractures, unspecified
+∞
13.9
13
*
W01
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
5.0
12.1
48
178
S72.3
ICD-10 Finland
Fracture of shaft of femur
138.2
11.7
12
*
T02.3
ICD-10 Finland
Fractures involving multiple regions of one lower limb
+∞
11.7
11
*
T02.8
ICD-10 Finland
Fractures involving other combinations of body regions
+∞
11.7
11
*
S32.0
ICD-10 Finland
Fracture of lumbar vertebra
17.4
11.1
17
12
ZXD05
NOMESCO Finland
Urgent procedure
4.6
11.0
44
162
S22.4
ICD-10 Finland
Multiple fractures of ribs
22.4
10.7
15
8
ZXE20
NOMESCO Finland
More than three and less than five hours
5.8
10.5
23
51
V49.9
ICD-10 Finland
Car occupant [any] injured in unspecified traffic accident
14.9
10.4
17
14
NFJ60
NOMESCO Finland
Internal fixation of fracture of other parts of femur with intramedullary nail
112.1
9.6
10
*
S32.7
ICD-10 Finland
Multiple fractures of lumbar spine and pelvis
41.6
9.3
11
*
NGU20
NOMESCO Finland
Removal of internal fixation device from knee or lower leg
23.0
8.8
12
6
X58
ICD-10 Finland
Exposure to other specified factors
4.5
8.7
27
80
T02.2
ICD-10 Finland
Fractures involving multiple regions of one upper limb
+∞
8.5
8
*
T02.7
ICD-10 Finland
Fractures involving thorax with lower back and pelvis with limb(s)
+∞
8.5
8
*
NEJ50
NOMESCO Finland
Operation of fracture of pelvic ring
+∞
8.5
8
*
T90.5
ICD-10 Finland
Sequelae of intracranial injury
37.3
8.3
10
*
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
5.2
8.0
19
45
NCU20
NOMESCO Finland
Removal of internal fixation device from elbow or forearm
87.5
7.5
8
*
T93.2
ICD-10 Finland
Sequelae of other fractures of lower limb
87.5
7.5
8
*
S72.1
ICD-10 Finland
Pertrochanteric fracture
17.8
7.5
11
7
S52.5
ICD-10 Finland
Fracture of lower end of radius
5.2
7.4
17
39
WX700
NOMESCO Finland
Respiratory and circulatory monitoring
4.0
6.8
23
72
NGJ62
NOMESCO Finland
Internal fixation of fracture of knee or lower leg using plate and screws, other or unspecified
75.3
6.5
7
*
ZZA00
NOMESCO Finland
Split skin graft
12.4
6.5
11
10
NFU20
NOMESCO Finland
Removal of internal fixation device from femur
29.1
6.3
8
*
NGJ70
NOMESCO Finland
External fixation of fracture of knee or lower leg, other or unspecified
+∞
6.3
6
*
NE1AA
NOMESCO Finland
Pelvis X-ray examination
6.1
6.1
16
31
W17
ICD-10 Finland
Other fall from one level to another
9.1
6.1
12
15
NCJ62
NOMESCO Finland
Internal fixation of fracture of forearm using plate
16.6
6.0
9
6
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
47
293
2.37
3.67
8.1
5.0
33.62
35.98
g/l
1.55
42
278
51
335
2.33
3.46
3.2
2.8
—
—
estimate
—
0
0
30
160
2.36
3.27
2.9
2.4
—
—
—
0
0
32
183
2.21
2.92
2.1
1.6
18.70
22.85
nmol/l
0.78
32
157
15
60
2.83
2.89
14.9
7.7
1.20
1.27
mmol/l
0.16
15
60
35
209
2.16
2.86
3.5
3.7
2.34
2.35
mmol/l
0.31
29
193
24
126
2.27
2.66
4.8
3.6
30.16
58.70
ng/l
0.64
19
97
43
288
2.01
2.51
2.6
2.0
88.24
99.63
pmol/l
1.06
30
143
7
17
4.39
2.41
1.7
1.5
—
—
—
0
0
19
97
2.24
2.22
6.5
6.5
1.06
1.03
mmol/l
0.23
19
92
46
332
1.85
2.02
16.5
8.0
1.21
1.21
mmol/l
0.27
41
285
17
88
2.17
1.92
1.6
1.8
—
—
—
0
0
5
12
4.36
1.85
2.0
3.8
—
2508.58
—
0
5
31
206
1.80
1.72
2.7
3.2
1632.49
1209.59
ng/l
0.29
24
168
10
41
2.63
1.71
21.1
9.9
24.61
25.40
mmol/l
—
10
41
8
33
2.57
1.58
15.2
10.7
26.62
25.09
mmol/l
—
8
33
8
33
2.57
1.58
1.0
1.2
—
—
—
0
0
19
113
1.88
1.47
1.8
1.9
—
—
—
0
0
9
41
2.34
1.42
1.8
1.8
—
—
—
0
0
19
118
1.79
1.29
4.1
2.8
0.33
2.81
e6/l
—
9
65
8
36
2.35
1.28
4.1
2.5
1.09
1.43
%
—
8
36
10
49
2.18
1.28
2.4
1.6
—
—
—
0
0
20
127
1.75
1.26
4.0
2.7
0.67
0.93
e6/l
—
10
74
15
89
1.83
1.17
1.6
1.8
—
—
—
0
0
28
200
1.60
1.14
4.4
2.8
0.22
0.32
e6/l
0.28
22
140
18
115
1.72
1.11
4.8
3.0
2.44
2.48
mmol/l
0.84
13
101
37
287
1.52
1.04
5.1
3.5
27.82
26.18
ng/l
0.10
25
197
6
27
2.31
0.95
1.7
2.2
—
—
—
0
0
12
71
1.81
0.95
4.1
3.8
—
—
—
0
0
5
23
2.25
0.77
1.6
1.1
10.80
10.92
g/l
—
5
23
5
26
1.98
0.72
1.6
1.2
4.32
4.38
g/l
—
5
26
5
26
1.98
0.72
1.6
1.2
4.28
3.77
g/l
—
5
26
5
26
1.98
0.72
1.6
1.2
8.54
7.65
g/l
—
5
26
74
693
1.57
0.60
26.6
16.0
27.33
22.83
mg/l
0.69
69
571
0
22
0.00
0.60
0.0
1.1
—
—
—
0
0
6
40
1.54
0.53
9.3
3.3
55.28
48.64
%
—
6
40
50
449
1.28
0.47
2.9
3.1
—
—
—
0
0
8
55
1.50
0.44
4.1
4.6
1.24
1.22
mmol/l
—
8
48
5
32
1.60
0.43
6.0
2.0
22.68
24.24
mmol/l
—
5
32
8
59
1.39
0.42
1.4
1.4
—
—
—
0
0
77
735
1.57
0.42
31.2
20.1
75.16
80.03
umol/l
1.06
77
727
0
17
0.00
0.41
0.0
1.9
—
390.71
—
0
7
0
18
0.00
0.40
0.0
1.4
—
—
—
0
0
26
219
1.27
0.39
4.1
4.1
11.05
11.18
mg/mmol
0.01
19
145
20
164
1.29
0.37
1.3
1.4
0.44
0.92
u/ml
—
5
46
6
85
0.68
0.35
1.5
2.3
—
—
—
0
0
10
129
0.74
0.31
1.2
1.4
5.58
7.17
u/ml
—
5
52
12
95
1.31
0.28
2.4
1.9
30.58
28.93
s
1.00
12
95
5
71
0.69
0.27
1.2
2.6
325.20
387.05
nmol/l
—
5
66
5
72
0.68
0.27
6.6
4.5
4.20
11.77
ug/l
—
5
61
5
74
0.66
0.27
1.6
2.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
11
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.7
—
—
—
0
0
0
10
0.00
0.21
0.0
1.3
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
12
0.00
0.21
0.0
1.6
—
—
—
0
0
0
12
0.00
0.21
0.0
1.2
—
184.13
—
0
12
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.4
—
—
—
0
0
77
753
1.27
0.15
36.0
23.7
91.59
91.16
fl
0.41
77
746
77
753
1.27
0.15
38.4
24.1
39.78
41.43
%
1.30
77
744
77
753
1.27
0.15
36.2
23.9
134.69
138.66
g/l
1.10
77
744
15
132
1.17
0.14
2.1
1.9
372.33
101739605.03
pmol/l
0.50
15
115
27
290
0.90
0.12
6.7
4.1
0.00
0.00
estimate
—
6
70
12
109
1.12
0.06
2.2
2.0
13.33
15.51
nmol/l
0.45
12
104
27
257
1.07
0.06
3.4
3.8
22.13
22.09
%
0.01
13
108
38
391
0.95
0.04
6.3
4.2
0.00
0.00
estimate
—
7
83
13
121
1.09
0.04
1.5
1.6
—
—
—
0
0
38
386
0.97
0.00
6.2
4.1
0.00
0.00
estimate
—
7
82
20
198
1.01
0.00
2.4
2.7
0.61
0.71
ug/l
0.38
11
108
22
215
1.03
0.00
5.9
4.0
0.00
0.00
estimate
—
6
77
67
671
0.99
0.00
24.0
15.1
85.01
83.22
ml/min/173m2
0.26
62
610
22
219
1.01
0.00
7.2
3.6
0.00
0.00
estimate
—
7
67
6
66
0.90
0.00
5.7
8.8
—
—
—
0
0
7
76
0.91
0.00
4.1
4.8
30.86
30.97
%
—
7
40
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
39
390
1.00
-0.00
6.2
4.2
0.00
0.00
estimate
—
7
80
0
8
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection
0
7
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.5
—
12.95
—
0
6
0
5
0.00
-0.00
0.0
1.0
—
16.26
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.4
—
16.53
—
0
7
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
892.83
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
6.20
—
0
6
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
6
62
0.97
-0.00
1.2
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.1
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS and mortality.
Females
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS | 1.38 [0.97, 1.97] | 0.075 |
| Birth year | 0.996 [0.99, 1.0] | 0.376 |
During the follow-up period (1.1.1998 — 31.12.2019), 74 out of 246 females with ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS died.
Males
| Parameter | HR [95% CI] | p-value |
|---|---|---|
| ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS | 1.784 [1.18, 2.69] | 0.006 |
| Birth year | 0.985 [0.98, 0.99] | 0.002 |
During the follow-up period (1.1.1998 — 31.12.2019), 78 out of 369 males with ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS died.
Mortality risk
Mortality risk for people of age
years, who have ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS.| N-year risk | Females | Males |
|---|---|---|
| 1 | 0.161% | 0.346% |
| 5 | 0.839% | 2.057% |
| 10 | 2.117% | 4.647% |
| 15 | 4.204% | 8.732% |
| 20 | 7.137% | 14.969% |
Relationships between endpoints
↥Index endpoint: ST19_FRACT_INVOLVI_MULTIPLE_BODY_REGIONS – Fractures involving multiple body regions
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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