Exposure to high and low air pressure and changes in air pressure

VWXY20_EXPOS_HIGH_LOW_AIR_PRESSURE_CHANG_AIR_PRESSURE

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — W94 Cause of death: ICD-10 — W94 2 out of 7 registries used, show all original rules.	54
4. Check minimum number of events None	54
5. Include endpoints None	54
6. Filter based on genotype QC (FinnGen only)	50

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy: 5
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: W8[5-9]|W9

NAME	VWXY20_EXPOS_HIGH_LOW_AIR_PRESSURE_CHANG_AIR_PRESSURE
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	W94
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	W94
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Exposure to high and low air pressure and changes in air pressure based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	50	20	30
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	49.85	47.24	51.60

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
51: Matched controls
510

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

W94

ICD-10 Finland

Exposure to high and low air pressure and changes in air pressure

+∞

73.0

T70.0

ICD-10 Finland

Otitic barotrauma

319.0

21.3

T70.3

ICD-10 Finland

Caisson disease [decompression sickness]

+∞

16.5

X58

ICD-10 Finland

Exposure to other specified factors

5.3

6.8

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3037467) Urinalysis macro (dipstick) panel - Urine

279

2.69

2.35

4.3

4.0

—

(3004119) Hemoglobin [Mass/volume] in Venous blood

4.33

2.34

1.0

2.3

136.71

139.17

g/l

—

(42870588) Differential panel, method unspecified - Blood

131

2.19

1.91

8.0

6.8

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

3.85

1.90

1.2

2.7

0.50

0.68

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

3.43

1.71

1.2

2.8

2.03

1.86

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

165

2.01

1.60

2.1

3.4

19.48

45.99

ng/l

0.57

(3024354) Oxygen [Partial pressure] in Venous blood

2.73

1.51

1.1

2.7

4.99

3.95

kpa

—

(3045414) Leukocytes [Presence] in Urine

0.00

1.41

0.0

1.9

—

0.00

—

(3015736) pH of Urine

190

1.89

1.39

2.6

3.0

6.39

6.16

0.43

105

(1002224) Polysomnography panel

2.37

1.28

1.1

—

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

2.80

1.24

1.2

1.3

—

(3022250) Lactate dehydrogenase [Enzymatic activity/volume] in Serum or Plasma by Lactate to pyruvate reaction

2.18

1.18

2.6

4.4

187.00

217.02

u/l

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

319

1.95

1.16

3.8

3.3

—

(3031040) Bacteria [#/volume] in Urine by Automated count

267

1.82

1.15

3.6

3.7

—

19.43

—

(3000991) Gas panel - Venous blood

2.09

1.01

15.4

10.0

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

223

1.70

1.01

4.6

8.7

12.45

11.23

umol/l

0.39

215

(3021447) Carbon dioxide [Partial pressure] in Venous blood

2.03

0.98

1.3

2.6

5.40

5.94

kpa

—

(3032080) INR in Blood by Coagulation assay

186

1.67

0.97

6.6

8.6

1.14

inr

0.03

153

(3022145) Colonoscopy Study observation

1.83

0.85

2.1

1.5

—

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

0.00

0.81

0.0

3.0

—

1.72

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

111

1.64

0.78

2.5

2.9

0.49

0.77

ug/l

1.99

(3000494) Fungus identified in Specimen by Culture

1.70

0.76

1.2

1.6

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

1.76

0.76

1.7

2.0

1.91

1.37

0.68

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.94

0.70

20.2

13.0

0.42

0.63

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

105

1.61

0.70

1.3

1.7

—

(3001019) Free T4 and TSH panel - Serum or Plasma

1.87

0.68

4.2

2.0

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.87

0.68

20.2

12.7

1.84

1.73

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

1.80

0.65

20.6

11.4

22.20

24.54

mmol/l

—

(3000492) Spirometry study

1.64

0.63

1.4

—

(3022313) Gas panel - Capillary blood

0.00

0.62

0.0

3.3

—

(3003327) Ova and parasites identified in Stool by Light microscopy

0.00

0.61

0.0

1.6

—

(3045424) Erythrocytes [Presence] in Urine

0.00

0.61

0.0

2.3

—

0.00

—

(3037121) Protein [Mass/volume] in Urine

0.00

0.61

0.0

3.3

—

254.56

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

203

1.45

0.59

3.2

2.8

61.67

110.87

ug/l

3.11

195

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.58

0.58

1.3

1.5

—

(40758558) Short blood count panel - Blood

129

1.48

0.55

6.3

5.5

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.57

0.53

1.2

1.4

—

(3019150) Specific gravity of Urine by Refractometry

1.49

0.50

1.9

3.7

1.02

kg/l

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.50

0.48

15.4

10.8

106.86

103.94

mmol/l

—

(3003694) ABO and Rh group [Type] in Blood

142

1.41

0.47

1.5

1.4

—

(3002109) Cholesterol in LDL/Cholesterol in HDL [Mass Ratio] in Serum or Plasma

1.51

0.43

3.3

2.0

3.77

3.29

ratio

—

(3027450) Sjogrens syndrome-B extractable nuclear Ab [Units/volume] in Serum

0.00

0.42

0.0

1.3

—

(4034850) Laboratory test

0.00

0.42

0.0

8.6

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

121

0.69

0.41

2.0

2.1

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.40

0.0

1.6

—

(3020779) Urea [Moles/volume] in Serum or Plasma

1.43

0.39

4.4

3.6

5.40

6.64

mmol/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.34

0.34

1.3

1.9

—

(3006504) Eosinophils/Leukocytes in Blood

207

1.30

0.34

10.5

6.5

2.66

2.97

0.41

200

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

1.41

0.33

3.2

2.7

2.37

2.44

mmol/l

—

(42868678) Cholesterol non HDL [Moles/volume] in Serum or Plasma

1.37

0.32

3.3

1.8

3.77

3.48

mmol/l

—

(3018010) Neutrophils/Leukocytes in Blood

210

1.27

0.29

10.1

6.3

54.06

57.88

1.32

205

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

152

1.28

0.29

3.0

3.6

30.67

29.99

u/l

0.06

146

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

1.27

0.29

1.8

2.0

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

437

1.54

0.28

17.8

15.4

24.51

22.69

mg/l

0.14

352

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

1.33

0.27

1.1

1.2

24.05

33.01

iu/ml

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.26

0.27

2.4

1.8

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

174

1.25

0.25

4.8

4.6

36.63

36.41

g/l

0.07

166

(3044640) Blood type and Crossmatch panel - Blood

145

1.26

0.25

4.5

2.6

—

(36660697) Celiac disease serology panel - Serum

1.31

0.23

1.0

1.3

—

(3013512) EKG study

127

1.26

0.23

2.8

2.7

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.24

0.22

1.2

3.5

—

(3012220) Varicella zoster virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.0

—

(3007778) Kappa light chains/Lambda light chains [Mass Ratio] in Serum

0.00

0.21

0.0

2.0

—

1.14

—

(3020044) Glucose [Moles/volume] in Cerebral spinal fluid

0.00

0.21

0.0

1.1

—

3.71

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

0.00

0.21

0.0

1.6

—

(3023183) Ammonium ion [Moles/volume] in Plasma

0.00

0.21

0.0

2.6

—

36.80

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.21

0.0

2.1

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

0.00

0.21

0.0

1.0

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

1.4

—

(3006184) Hemoglobin [Mass/volume] in Capillary blood

0.00

0.21

0.0

1.8

—

139.80

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

3.1

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.21

0.0

1.2

—

(40768800) Prostate Pathology biopsy report

0.00

0.21

0.0

1.4

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.9

—

26.36

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

0.00

0.21

0.0

1.9

—

39.92

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

0.21

0.0

1.7

—

(3014148) Varicella zoster virus Ab [Titer] in Serum

0.00

0.21

0.0

1.1

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.3

—

(3025245) SCL-70 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

0.00

0.21

0.0

1.4

—

(3005033) Fetal Nuchal fold Thickness US

0.00

0.21

0.0

1.3

—

1.30

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

0.00

0.20

0.0

2.1

—

(3015235) Bicarbonate [Moles/volume] in Capillary blood

0.00

0.20

0.0

1.5

—

24.69

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.20

0.0

1.6

—

(3051387) C reactive protein [Mass/volume] in Capillary blood

0.00

0.20

0.0

4.5

—

15.94

—

(3007853) Bacteria identified in Skin by Aerobe culture

1.20

0.20

2.8

1.6

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

1.15

0.18

2.6

1.8

2.10

2.21

g/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

140

1.21

0.18

3.8

3.2

—

(1761868) Lipid panel - Serum or Plasma

219

1.18

0.17

3.8

2.9

—

(40760892) CBC W Ordered Manual Differential panel - Blood

129

0.81

0.17

3.7

4.3

—

(3042936) Bacteria identified in Isolate by Culture

1.13

0.17

2.9

2.1

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

432

1.35

0.17

15.2

14.6

87.91

88.80

ml/min/173m2

0.14

401

(3015377) Calcium [Moles/volume] in Serum or Plasma

131

1.21

0.17

2.3

2.6

2.34

2.35

mmol/l

0.20

121

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.17

0.16

3.0

2.0

—

(3023368) Bacteria identified in Blood by Culture

113

1.20

0.15

4.8

5.3

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

144

1.16

0.12

3.8

4.4

16.11

21.67

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

175

1.14

0.10

3.1

2.5

73.21

71.38

nmol/l

0.09

164

(40761511) CBC panel - Blood by Automated count

466

0.87

0.10

11.8

13.2

—

(3005772) Bilirubin.conjugated [Moles/volume] in Serum or Plasma

1.07

0.10

2.2

3.3

3.40

4.59

umol/l

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

107

1.16

0.09

5.3

2.7

—

(40768797) Stomach Pathology biopsy report

1.10

0.09

1.0

1.3

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.07

0.08

2.4

1.8

14.99

13.73

umol/l

—

(3018095) Leukocytes [#/volume] in Urine

152

0.89

0.07

5.8

3.4

33.24

16.82

e6/l

—

105

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

100

0.88

0.07

1.7

—

(3030467) Casts [#/volume] in Urine by Automated count

109

1.13

0.07

4.5

2.7

0.30

0.44

e6/l

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

171

0.91

0.06

2.4

1.8

91.14

93.83

pmol/l

—

(36304419) Bacteria [Presence] in Urine

110

1.12

0.05

4.5

2.7

—

estimate

—

(3020682) Albumin/Creatinine [Ratio] in Urine

126

0.94

0.01

4.3

4.0

0.80

7.81

mg/mmol

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

214

1.05

0.00

4.3

2.8

—

estimate

—

(3012516) Albumin [Mass/volume] in Urine

123

0.97

0.00

3.3

3.6

7.33

50.20

mg/l

—

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

177

1.03

0.00

6.3

4.7

1.69

1.70

ug/l

0.00

160

(40768804) Tissue Pathology biopsy report

174

0.97

0.00

1.7

1.8

—

(3026008) Bacteria identified in Urine by Culture

102

0.98

0.00

2.5

2.2

—

(21494755) Public health laboratory ask at order entry panel

1.01

0.00

1.5

1.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

0.91

-0.00

1.4

1.8

—

(3003129) Base excess in Capillary blood by calculation

0.00

-0.00

0.0

1.2

—

-0.42

—

(3021952) Alkaline phosphatase isoenzymes [Enzymatic activity/volume] in Serum or Plasma by Heat stability

0.00

-0.00

0.0

2.0

—

(40767503) Oxygen content in Capillary blood by calculation

0.00

-0.00

0.0

2.3

—

16.37

—

(3032700) Glomerular basement membrane Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.4

—

(44806118) Parainfluenza type 4 nucleic acid detection

0.00

-0.00

0.0

1.2

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

0.00

-0.00

0.0

1.8

—

(3049539) Genetic diseases [Identifier] in Blood or Tissue by FISH Nominal

0.00

-0.00

0.0

1.5

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

-0.00

0.0

3.0

—

(3019832) Treponema pallidum Ab [Presence] in Serum

0.87

-0.00

2.0

1.8

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

446

1.08

-0.00

19.8

16.4

139.78

139.75

mmol/l

0.03

439

(3045142) Bone marrow Pathology biopsy report

0.00

-0.00

0.0

1.5

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

-0.00

0.0

1.1

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

14.2

—

991.20

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.2

—

(3013290) Carbon dioxide [Partial pressure] in Blood

0.00

-0.00

0.0

3.4

—

5.39

—

(3028369) Herpes simplex virus 1+2 DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3014702) Chromogranin A [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.6

—

1.99

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

1.5

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

3.0

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

0.00

-0.00

0.0

1.5

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.2

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

210.40

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

448

1.04

-0.00

19.9

16.5

3.92

3.96

mmol/l

0.66

440

(3045716) Anion gap in Serum or Plasma by calculation

0.00

-0.00

0.0

2.2

—

11.17

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

0.96

-0.00

2.2

1.5

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.1

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(40765096) Chromosome analysis panel by Banding

0.00

-0.00

0.0

1.6

—

(44790048) Parainfluenza type 2 nucleic acid detection

0.00

-0.00

0.0

1.2

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.0

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(3025149) Bordetella pertussis IgA Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.2

—

(3003181) Sodium [Moles/volume] in Urine

0.00

-0.00

0.0

1.6

—

70.89

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

2.0

—

(3044927) Protein electrophoresis panel - Urine

0.00

-0.00

0.0

1.2

—

(3044242) Glucose [Moles/volume] in Arterial blood

0.00

-0.00

0.0

14.2

—

7.10

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.4

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

1057.40

—

(3014973) Borrelia burgdorferi IgM Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.4

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

3.0

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

6.8

—

0.64

—

(3042631) Mycobacterium sp identified in Specimen

0.00

-0.00

0.0

1.8

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

0.00

-0.00

0.0

1.8

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.3

—

(44790047) Parainfluenza type 1 nucleic acid detection

0.00

-0.00

0.0

1.2

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

25.60

—

(3028167) CD3+CD4+ (T4 helper) cells [#/volume] in Blood

0.00

-0.00

0.0

2.0

—

0.37

—

(3001308) Cholesterol in LDL [Moles/volume] in Serum or Plasma

459

1.02

-0.00

6.0

5.3

2.95

2.79

mmol/l

0.56

441

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

-0.00

0.0

4.4

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.4

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

-0.00

0.0

1.2

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

-0.00

0.0

1.6

—

(3005570) Glucose [Moles/volume] in Urine

0.00

-0.00

0.0

1.7

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

-0.00

0.0

1.4

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.4

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

12.63

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

-0.00

0.0

1.3

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

-0.00

0.0

1.4

—

21.00

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

3.0

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

-0.00

0.0

1.4

—

(3027315) Oxygen [Partial pressure] in Blood

0.00

-0.00

0.0

3.4

—

8.55

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

-0.00

0.0

2.2

—

1.58

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

-0.00

0.0

1.4

—

(44790049) Parainfluenza type 3 nucleic acid detection

0.00

-0.00

0.0

1.2

—

(3039162) Centromere protein B Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(3037756) Immunofixation for Serum or Plasma

0.00

-0.00

0.0

1.4

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

-0.00

0.0

1.3

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

3.0

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

3.0

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

20.2

—

1763.40

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

-0.00

0.0

1.8

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.00

-0.00

2.2

1.5

—

Mortality – FinRegistry

↥

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

↥

Index endpoint: VWXY20_EXPOS_HIGH_LOW_AIR_PRESSURE_CHANG_AIR_PRESSURE – Exposure to high and low air pressure and changes in air pressure

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

≡ Risteys

R14

FinnGen R13 + FinRegistry

FinnGen R12 + FinRegistry

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Exposure to high and low air pressure and changes in air pressure

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Exposure to high and low air pressure and changes in air pressure (VWXY20_EXPOS_HIGH_LOW_AIR_PRESSURE_CHANG_AIR_PRESSURE)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Relationships between endpoints