Arthropathy in hypersensitivity reactions classified elsewhere

ARTHROPATHY_HYPERSENS

arthritis: An inflammatory process affecting a joint. Causes include infection, autoimmune processes, degenerative processes, and trauma. Signs and symptoms may include swelling around the affected joint and pain.

Suggest a new description

Endpoint definition

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Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — M36.4, M36.4D69.0 Cause of death: ICD-10 — M36.4, M36.4D69.0 2 out of 7 registries used, show all original rules.	52
4. Check minimum number of events None	52
5. Include endpoints None	52
6. Filter based on genotype QC (FinnGen only)	49

Control definitions (FinnGen only)

Control exclude: SYSTINOTH_FG

Extra metadata

First used in FinnGen datafreeze: DF2

NAME	ARTHROPATHY_HYPERSENS
CONTROL_EXCLUDE	SYSTINOTH_FG
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	M364
HD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	M364
COD_ICD_9	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

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List of similar endpoints to Arthropathy in hypersensitivity reactions classified elsewhere based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

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-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	839	349	489
Only index persons	660	280	380
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	8.38	8.71	8.09
Only index persons	11.65	12.89	10.73

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	49	29	20
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	31.30	28.31	35.63

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
50: Matched controls
500

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

M36.4*D69.0

ICD-10 Finland

Arthropathy in Henoch(-Schönlein) purpura

+∞

64.2

D69.0

ICD-10 Finland

Allergic purpura

388.8

34.5

N08.2*D69.0

ICD-10 Finland

Glomerular disorders in Henoch(-Schönlein) purpura

+∞

15.4

H02AB06

ATC

prednisolone; systemic

6.5

9.3

132

M36.4

ICD-10 Finland

Arthropathy in hypersensitivity reactions classified elsewhere

+∞

8.6

KA3AT

NOMESCO Finland

Biopsy of kidney with ultrasound guidance

53.7

8.0

N08.2

ICD-10 Finland

Glomerular disorders in blood diseases and disorders involving the immune mechanism

+∞

7.5

A12AX

ATC

Calcium, combinations with vitamin D and/or other drugs

4.6

6.6

L95.9

ICD-10 Finland

Vasculitis limited to skin, unspecified

+∞

6.4

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3037522) Nuclear Ab [Titer] in Serum

14.31

20.92

1.8

1.4

457.14

458.18

titre

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

34.84

16.43

2.1

1.2

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

14.48

10.02

1.5

1.1

0.24

0.25

g/l

0.12

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

13.65

9.75

1.5

1.1

1.26

1.21

g/l

0.29

(3004588) Protein electrophoresis panel - Serum or Plasma

13.36

8.17

1.5

4.2

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

140

5.46

7.77

11.2

3.4

—

(3002582) Erythrocytes [#/volume] in Urine

139

5.04

7.16

10.0

3.1

32.75

45.97

e6/l

0.24

104

(3020779) Urea [Moles/volume] in Serum or Plasma

7.74

7.14

8.6

11.7

7.89

6.77

mmol/l

0.28

(3018677) aPTT in Platelet poor plasma by Coagulation assay

5.42

7.00

5.6

2.9

28.17

29.00

0.43

(42870588) Differential panel, method unspecified - Blood

141

4.94

6.99

13.5

5.9

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

15.21

6.97

1.6

1.2

3.90

3.67

g/l

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

15.21

6.97

1.6

1.2

7.20

7.78

g/l

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

15.21

6.97

1.6

1.2

4.95

4.69

g/l

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

17.39

6.72

1.5

1.1

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

21.43

6.53

1.8

1.0

10.74

9.72

g/l

—

(3022096) Basophils/Leukocytes in Blood

197

5.45

6.49

13.8

6.1

0.63

0.01

192

(3006504) Eosinophils/Leukocytes in Blood

200

5.32

6.28

13.7

6.0

2.34

2.81

0.62

194

(3024561) Albumin [Mass/volume] in Serum or Plasma

150

4.53

6.23

12.3

4.6

35.80

35.93

g/l

0.04

145

(3019069) Monocytes/Leukocytes in Blood

201

5.27

6.22

13.8

6.0

7.39

8.48

2.43

196

(3018095) Leukocytes [#/volume] in Urine

167

4.65

6.16

12.7

3.8

9.15

29.79

e6/l

2.20

109

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

13.49

6.10

1.6

1.2

2.82

2.67

g/l

—

(3023520) Reticulocytes [#/volume] in Blood

7.04

5.76

2.9

3.5

74.11

68.91

e9/l

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

18.61

5.61

1.8

1.0

0.00

g/l

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

13.36

5.54

1.7

1.3

0.11

0.69

g/l

—

(3030467) Casts [#/volume] in Urine by Automated count

121

3.99

5.49

10.0

2.8

0.06

0.41

e6/l

1.51

(3007164) IgA [Mass/volume] in Serum or Plasma

123

3.90

5.33

1.9

1.5

3.04

2.14

g/l

1.85

(3000850) Epithelial cells [#/volume] in Urine

3.88

5.14

8.6

2.8

2.84

6.18

e6/l

1.69

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

4.10

5.13

7.4

2.7

1.30

3.76

e6/l

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

3.96

5.02

6.4

2.6

0.26

1.10

e6/l

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

13.27

4.97

1.8

1.3

0.00

g/l

—

(36304419) Bacteria [Presence] in Urine

120

3.72

4.97

10.4

2.8

—

estimate

—

(3015171) Extractable nuclear Ab [Units/volume] in Serum

7.51

4.56

1.5

1.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

4.13

4.49

1.3

1.7

—

(3037756) Immunofixation for Serum or Plasma

13.26

4.42

1.4

1.0

—

(40768443) Skin Pathology biopsy report

7.05

4.39

1.2

1.1

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

5.82

4.16

3.5

1.4

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

6.29

4.08

6.6

3.5

101.60

90.89

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

301

4.05

3.71

10.4

4.0

14.79

9.10

mm/h

1.31

283

(40758558) Short blood count panel - Blood

140

3.02

3.58

9.4

5.8

—

(3000991) Gas panel - Venous blood

4.03

3.47

8.8

10.9

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

4.18

3.40

9.0

12.1

4.98

5.10

kpa

0.24

(3022313) Gas panel - Capillary blood

4.40

3.34

10.9

11.7

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

5.73

3.20

7.9

3.6

2.88

3.31

g/l

—

(3030366) Cystatin C [Mass/volume] in Serum or Plasma

4.98

3.17

12.7

11.2

0.93

1.15

mg/l

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.95

3.14

1.4

1.6

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

10.90

3.04

1.2

1.0

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

10.90

3.04

1.0

1.2

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

7.39

2.95

4.8

1.1

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

160

2.70

2.95

13.2

9.2

1.22

mmol/l

0.08

152

(3016650) Hepatitis A virus Ab [Presence] in Serum

9.07

2.81

1.0

—

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

9.07

2.81

1.0

—

(3007853) Bacteria identified in Skin by Aerobe culture

3.27

2.78

2.1

1.8

—

(3015736) pH of Urine

182

2.62

2.74

6.8

3.1

5.66

6.32

3.11

(3035350) Ketones [Presence] in Urine by Test strip

230

2.74

2.70

7.0

3.4

0.00

estimate

—

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

3.42

2.62

7.5

5.7

24.30

24.18

mmol/l

0.07

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

7.77

2.61

1.2

1.0

—

(3021601) Nitrite [Presence] in Urine by Test strip

234

2.65

2.54

6.8

3.4

0.00

estimate

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

3.04

2.49

7.3

8.5

5.62

5.70

kpa

0.15

(3023368) Bacteria identified in Blood by Culture

2.60

2.45

5.3

3.8

—

(3009261) Glucose [Presence] in Urine by Test strip

237

2.59

2.43

7.0

3.5

0.00

estimate

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

6.79

2.43

1.4

6.4

31.48

33.39

mg/l

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

6.79

2.43

1.4

6.4

23.34

26.05

mg/l

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

3.12

2.22

6.7

14.5

22.88

24.88

mmol/l

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

223

2.41

2.22

4.3

2.7

176.68

87.31

ug/l

0.50

208

(3021589) Normoblasts [#/volume] in Blood

205

2.35

2.17

15.3

9.0

0.00

e9/l

-0.00

153

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

3.89

2.14

1.1

1.3

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

118

2.34

2.14

4.0

2.0

47.38

53.81

u/l

0.69

109

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

5.41

2.12

1.2

1.3

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

4.39

2.11

2.0

1.7

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

3.70

2.05

1.9

3.2

—

(3034770) Mitochondria Ab [Titer] in Serum

4.50

1.87

1.0

1.3

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

3.64

1.80

1.2

1.3

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

4.14

1.76

2.2

—

(3025941) Bacteria identified in Stool by Culture

3.44

1.72

1.2

1.4

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

2.23

1.71

1.8

—

(3026493) Urate [Moles/volume] in Serum or Plasma

2.23

1.71

2.8

3.1

385.81

322.74

umol/l

1.55

(3019225) pH of Specimen

2.78

1.68

9.7

3.6

7.22

7.26

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

175

2.01

1.58

4.0

2.3

66.79

75.24

nmol/l

0.86

160

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

2.66

1.55

3.3

1.8

30.89

27.12

u/l

—

(3026008) Bacteria identified in Urine by Culture

107

2.07

1.52

4.2

2.6

—

(4035726) Immunohistochemistry procedure

2.74

1.51

1.3

1.1

—

(3000494) Fungus identified in Specimen by Culture

2.45

1.46

4.1

1.3

—

(3037551) Cancer Ag 125 [Units/volume] in Serum or Plasma

3.15

1.39

1.2

2.5

41.40

89.00

u/ml

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

2.70

1.35

1.5

1.4

—

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

404

0.50

1.30

5.1

4.5

2.03

1.86

mu/l

0.47

374

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

117

1.84

1.15

1.7

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.07

1.13

4.3

1.9

—

(3028626) Oxygen [Partial pressure] in Capillary blood

2.53

1.11

12.6

17.6

10.58

9.06

kpa

—

(3008898) HLA-B27 [Presence]

2.41

1.06

1.2

1.1

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.16

1.05

4.7

11.9

1.36

1.27

mmol/l

—

(3044640) Blood type and Crossmatch panel - Blood

129

1.76

1.04

4.7

2.0

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

2.21

0.93

1.3

1.9

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.02

0.93

1.5

1.9

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.97

0.91

1.5

1.8

—

(3042936) Bacteria identified in Isolate by Culture

1.92

0.89

3.5

2.3

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

145

1.63

0.84

1.9

2.4

—

(40768797) Stomach Pathology biopsy report

1.85

0.81

1.4

1.2

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

139

1.59

0.76

1.5

1.4

1.10

1.25

u/ml

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

122

1.60

0.73

4.5

2.5

2.31

2.38

mmol/l

0.55

111

(3024354) Oxygen [Partial pressure] in Venous blood

1.73

0.70

10.6

9.1

6.71

5.09

kpa

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

1.70

0.69

3.4

3.5

16.88

22.55

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.62

0.0

2.2

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.81

0.60

1.3

2.2

—

(3005322) IgE [Units/volume] in Serum or Plasma

1.81

0.60

1.0

1.3

96.40

155.52

u/ml

—

(40760892) CBC W Ordered Manual Differential panel - Blood

1.56

0.58

3.8

5.2

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.66

0.56

1.0

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

138

1.48

0.56

2.1

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

1.57

0.53

5.3

4.8

26.33

30.78

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

100

0.65

0.45

1.7

2.6

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.42

0.0

1.6

—

49.54

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

146

1.36

0.40

2.7

1.7

89.94

93.62

pmol/l

0.08

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

100

1.41

0.38

5.2

1.9

—

(3002256) Pathology report gross observation

1.49

0.37

1.2

1.1

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.45

0.36

9.0

9.8

101.67

104.88

mmol/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

106

0.71

0.33

2.0

2.9

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.28

0.27

1.7

1.4

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.39

0.24

1.2

1.4

—

(3020961) Endomysium IgA Ab [Titer] in Serum

1.35

0.24

1.2

1.3

—

(3019832) Treponema pallidum Ab [Presence] in Serum

103

0.73

0.24

1.9

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

195

0.81

0.23

5.4

2.5

—

estimate

—

(3002385) Erythrocyte [DistWidth] in Red Blood Cells

389

1.30

0.23

34.6

13.9

13.68

13.32

0.85

383

(3013512) EKG study

110

0.78

0.23

3.9

3.4

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.21

0.0

1.1

—

(3032773) Endomysium IgG Ab [Titer] in Serum

0.00

0.21

0.0

1.1

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.21

0.0

1.5

—

(3014599) Egg white IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.9

—

5.46

—

(3022145) Colonoscopy Study observation

1.31

0.21

1.7

1.3

—

(3025130) Human papilloma virus identified in Specimen

0.00

0.21

0.0

1.9

—

(40768793) Breast Pathology biopsy report

0.00

0.21

0.0

1.3

—

(3023430) Cat dander IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

2.07

—

(3014133) Dog dander IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.0

—

7.36

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.21

0.0

1.2

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

342

0.82

0.20

3.8

3.7

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

1.15

0.18

6.0

2.3

2.49

2.45

mmol/l

—

(36660697) Celiac disease serology panel - Serum

1.13

0.09

1.2

1.1

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

0.80

0.08

2.0

2.4

—

(3003694) ABO and Rh group [Type] in Blood

140

1.10

0.05

1.5

—

(40768804) Tissue Pathology biopsy report

141

0.99

0.00

2.2

1.8

—

(1761868) Lipid panel - Serum or Plasma

163

0.97

0.00

2.3

2.9

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

0.0

1.2

—

(3011897) Casein IgE Ab [Units/volume] in Serum

0.00

0.0

2.0

—

5.07

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.0

1.3

—

1.58

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

0.0

1.2

—

(44816844) Macroprolactin [Units/volume] in Serum or Plasma

0.00

0.0

1.2

—

236.67

—

(3016244) Insulin [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

2.3

—

7.94

—

(3033386) Bacteria [Presence] in Cerebral spinal fluid by Light microscopy

0.00

-0.00

0.0

1.0

—

(3021901) Oxygen saturation in Capillary blood

0.00

-0.00

0.0

12.2

—

94.24

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.6

—

(40768800) Prostate Pathology biopsy report

0.00

-0.00

0.0

1.2

—

(3023659) Complement C1 esterase inhibitor.functional/Complement C1 esterase inhibitor.total in Serum or Plasma

0.00

-0.00

0.0

1.0

—

106.00

—

(3003245) Complement C1 esterase inhibitor [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

0.30

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

-0.00

0.0

1.3

—

18.86

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

0.00

-0.00

0.0

1.6

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

7.21

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

-0.00

0.0

3.6

—

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

0.00

-0.00

0.0

1.0

—

169.80

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

-0.00

0.0

1.7

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

6.6

—

226.60

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

3.4

—

3.77

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

-0.00

0.0

2.4

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

-0.00

0.0

1.0

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3014326) Insulin-like growth factor-I [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.6

—

21.32

—

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.1

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3000492) Spirometry study

0.90

-0.00

1.2

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.5

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

0.91

-0.00

2.0

2.2

—

(3011841) English Walnut IgE Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

2.17

—

Mortality – FinRegistry

↥

Association

Association between endpoint ARTHROPATHY_HYPERSENS and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have ARTHROPATHY_HYPERSENS.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: ARTHROPATHY_HYPERSENS – Arthropathy in hypersensitivity reactions classified elsewhere

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Arthropathy in hypersensitivity reactions classified elsewhere

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints