Relapsing polychondritis

M13_RELAPSPOLYCHONDR

relapsing polychondritis: Relapsing polychondritis (RP) is a rare, clinically heterogeneous, multisystemic inflammatory disease characterized by inflammation of the cartilage and proteoglycan rich structures leading to cartilage damage with joint, ocular and cardiovascular involvement.

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Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 M94.1
  • Cause of death: ICD-10 M94.1

2 out of 7 registries used, show all original rules.

83

4. Check minimum number of events

None

83

5. Include endpoints

None

83

6. Filter based on genotype QC (FinnGen only)

80

Control definitions (FinnGen only)

Control exclude
M13_OTHERBONE

Extra metadata

Level in the ICD hierarchy
4
First used in FinnGen datafreeze
DF2
Parent code in ICD-10
M94
Name in latin
Polychondritis recidiva

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: unknown.

No upset table: unknown.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 349 227 121
Only index persons 333 217 116
Unadjusted period prevalence (%)
Whole population 0.01 0.01 0.00
Only index persons 0.01 0.01 0.00
Median age at first event (years)
Whole population 52.03 50.64 54.42
Only index persons 51.38 50.03 53.90

-FinnGen-

Key figures

All Female Male
Number of individuals 80 56 24
Unadjusted period prevalence (%) 0.02 0.02 0.01
Median age at first event (years) 51.31 49.81 54.81

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
83
Matched controls
830
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
M941, ,
ICD-10 Finland
Relapsing polychondritis
+∞
119.5
83
*
J01DB01, ,
ATC
cefalexin; oral
+∞
111.5
80
*
A98, ,
ICD-O-3
+∞
109.2
79
*
M01AE01, ,
ATC
ibuprofen; systemic, rectal
+∞
106.9
78
*
N02BE01, ,
ATC
paracetamol; systemic, rectal
+∞
96.8
73
*
J01AA02, ,
ATC
doxycycline; systemic
+∞
87.7
68
*
H02AB06, ,
ATC
prednisolone; systemic
+∞
87.7
68
*
A02BC02, ,
ATC
pantoprazole; systemic
+∞
82.6
65
*
SAA01, ,
ICD-O-3
+∞
77.7
62
*
J01CA04, ,
ATC
amoxicillin; systemic
+∞
77.7
62
*
WX110, ,
ICD-O-3
+∞
68.5
56
*
J01FA10, ,
ATC
azithromycin; systemic
+∞
65.5
54
*
J01DA01, ,
ATC
[U] cefalexin
+∞
65.5
54
*
SAA02, ,
ICD-O-3
+∞
64.1
53
*
R03AC02, ,
ATC
salbutamol; inhalant
+∞
64.1
53
*
M01AH05, ,
ATC
etoricoxib; oral
+∞
62.6
52
*
GD1AA, ,
ICD-O-3
+∞
61.2
51
*
L04AX03, ,
ATC
methotrexate; systemic
+∞
61.2
51
*
J01FA06, ,
ATC
roxithromycin; oral
+∞
58.4
49
*
M03BX02, ,
ATC
tizanidine; oral
+∞
58.4
49
*
J01CE02, ,
ATC
phenoxymethylpenicillin; oral
+∞
58.4
49
*
K021, ,
ICD-O-3
+∞
58.4
49
*
J01CR02, ,
ATC
amoxicillin and beta-lactamase inhibitor; systemic
+∞
58.4
49
*
M01AB05, ,
ATC
diclofenac; systemic, rectal
+∞
57.0
48
*
J02AC01, ,
ATC
fluconazole; systemic
+∞
57.0
48
*
SFA20, ,
ICD-O-3
+∞
55.6
47
*
M01AE02, ,
ATC
naproxen; oral, rectal
+∞
55.6
47
*
202, ,
Kela drug reimbursment
Connective tissue diseases, rheumatoid arthritis and comparable disease
+∞
52.9
45
*
SFA10, ,
ICD-O-3
+∞
52.9
45
*
R06AE07, ,
ATC
cetirizine; oral
+∞
52.9
45
*
EB1AA, ,
ICD-O-3
+∞
52.9
45
*
S01XA20, ,
ATC
artificial tears and other indifferent preparations; ophthalmic
+∞
51.5
44
*
N02AJ06, ,
ATC
codeine and paracetamol; systemic
+∞
50.2
43
*
A12AX, ,
ATC
Calcium, combinations with vitamin D and/or other drugs
+∞
48.9
42
*
UJD10, ,
ICD-O-3
+∞
47.5
41
*
WYA05, ,
ICD-O-3
+∞
47.5
41
*
ZXE00, ,
ICD-O-3
+∞
47.5
41
*
A02BC05, ,
ATC
esomeprazole; systemic
+∞
47.5
41
*
M941, ,
ICD-O-3
+∞
44.9
39
*
E0000UV, ,
ATC
+∞
44.9
39
*
KMAK, ,
ICD-O-3
+∞
43.6
38
*
C07AB07, ,
ATC
bisoprolol; oral
+∞
43.6
38
*
J069, ,
ICD-O-3
+∞
42.4
37
*
R01AD09, ,
ATC
mometasone; nasal
+∞
42.4
37
*
J01FF01, ,
ATC
clindamycin; systemic
+∞
41.1
36
*
ZXD10, ,
ICD-O-3
+∞
41.1
36
*
WX290, ,
ICD-O-3
+∞
41.1
36
*
S01CA01, ,
ATC
dexamethasone and antiinfectives; ophthalmic
+∞
41.1
36
*
J01FA09, ,
ATC
clarithromycin; systemic
+∞
41.1
36
*
WZB00, ,
ICD-O-3
+∞
39.8
35
*
EB1SA, ,
ICD-O-3
+∞
39.8
35
*
-1, ,
ICD-O-3
+∞
39.8
35
*
Z871, ,
ICD-O-3
+∞
39.8
35
*
N02AX02, ,
ATC
tramadol; systemic, rectal
+∞
38.6
34
*
N02AA59, ,
ATC
codeine, combinations excl. psycholeptics; systemic
+∞
38.6
34
*
M796, ,
ICD-O-3
+∞
38.6
34
*
SFA30, ,
ICD-O-3
+∞
38.6
34
*
SDA03, ,
ICD-O-3
+∞
38.6
34
*
J01MA02, ,
ATC
ciprofloxacin; systemic
+∞
38.6
34
*
ZXE10, ,
ICD-O-3
+∞
37.3
33
*
M01AE03, ,
ATC
ketoprofen; systemic, rectal
+∞
37.3
33
*
G03CA03, ,
ATC
estradiol; nasal, systemic, rectal, transdermal, vaginal
+∞
37.3
33
*
R01AD08, ,
ATC
fluticasone; nasal
+∞
37.3
33
*
P01AB01, ,
ATC
metronidazole; oral, rectal
+∞
37.3
33
*
EB1HA, ,
ICD-O-3
+∞
37.3
33
*
M01AC06, ,
ATC
meloxicam; systemic, rectal
+∞
37.3
33
*
Z3231, ,
ICD-O-3
+∞
36.1
32
*
S18, ,
ICD-O-3
+∞
34.9
31
*
R104, ,
ICD-10 Finland
Other and unspecified abdominal pain
+∞
34.9
31
*
SPAT1256, ,
ICD-O-3
+∞
34.9
31
*
R74, ,
ICD-O-3
+∞
34.9
31
*
J01CA08, ,
ATC
pivmecillinam; oral
+∞
33.6
30
*
Z2221, ,
ICD-O-3
+∞
33.6
30
*
Z012, ,
ICD-O-3
+∞
32.4
29
*
SPAT1263, ,
ICD-O-3
+∞
32.4
29
*
ZXD05, ,
ICD-O-3
+∞
32.4
29
*
M02AA07, ,
ATC
piroxicam; topical
+∞
32.4
29
*
B01AB05, ,
ATC
enoxaparin; parenteral
+∞
32.4
29
*
SPAT1249, ,
ICD-O-3
+∞
31.2
28
*
R05FA02, ,
ATC
opium derivatives and expectorants; systemic
+∞
31.2
28
*
SAA03, ,
ICD-O-3
+∞
30.0
27
*
WZC00, ,
ICD-O-3
+∞
30.0
27
*
EBA00, ,
ICD-O-3
+∞
30.0
27
*
D07AC01, ,
ATC
betamethasone; topical
+∞
28.8
26
*
A02BC03, ,
ATC
lansoprazole; oral
+∞
28.8
26
*
SCA01, ,
ICD-O-3
+∞
28.8
26
*
D82, ,
ICD-O-3
+∞
28.8
26
*
M255, ,
ICD-O-3
+∞
28.8
26
*
R03BA05, ,
ATC
fluticasone; inhalant
+∞
28.8
26
*
N05CF01, ,
ATC
zopiclone; oral
+∞
27.6
25
*
I10, ,
ICD-10 Finland
Essential (primary) hypertension
+∞
27.6
25
*
R01AD12, ,
ATC
fluticasone furoate; nasal
+∞
27.6
25
*
R06AX27, ,
ATC
desloratadine; oral
+∞
27.6
25
*
R4110, ,
ICD-O-3
+∞
27.6
25
*
SDA02, ,
ICD-O-3
+∞
26.5
24
*
Z018, ,
ICD-10 Finland
Other specified special examinations
+∞
26.5
24
*
R01BA52, ,
ATC
pseudoephedrine, combinations; oral
+∞
26.5
24
*
R05FB02, ,
ATC
cough suppressants and expectorants; systemic
+∞
26.5
24
*
J05AB01, ,
ATC
aciclovir; systemic
+∞
26.5
24
*
A02BC01, ,
ATC
omeprazole; systemic
+∞
26.5
24
*
SDA01, ,
ICD-O-3
+∞
25.3
23
*
UJF32, ,
ICD-O-3
+∞
25.3
23
*
R05DA20, ,
ATC
opium alkaloids and derivatives - combinations
+∞
25.3
23
*
M545, ,
ICD-O-3
+∞
25.3
23
*
H02AB07, ,
ATC
prednisone; oral
+∞
25.3
23
*
R05, ,
ICD-O-3
+∞
25.3
23
*
I10, ,
ICD-O-3
+∞
25.3
23
*
L17, ,
ICD-O-3
+∞
25.3
23
*
J01DA09, ,
ATC
[U] cefadroxil
+∞
24.1
22
*
A03FA01, ,
ATC
metoclopramide; systemic, rectal
+∞
24.1
22
*
H03AA01, ,
ATC
levothyroxine sodium; systemic
+∞
24.1
22
*
N03AX16, ,
ATC
[U] pregabalin
+∞
24.1
22
*
C10AA01, ,
ATC
simvastatin; oral
+∞
24.1
22
*
D19, ,
ICD-O-3
+∞
24.1
22
*
AA1AD, ,
ICD-O-3
+∞
24.1
22
*
R03DC03, ,
ATC
montelukast; oral
+∞
24.1
22
*
W01, ,
ICD-10 Finland
Fall on same level from slipping, tripping and stumbling
+∞
24.1
22
*
D07AB02, ,
ATC
hydrocortisone butyrate; topical
+∞
24.1
22
*
M796, ,
ICD-10 Finland
Pain in limb
+∞
24.1
22
*
D07AC13, ,
ATC
mometasone; topical
+∞
24.1
22
*
S01GX01, ,
ATC
cromoglicic acid; ophthalmic
+∞
23.0
21
*
N05BA04, ,
ATC
oxazepam; oral
+∞
23.0
21
*
L08, ,
ICD-O-3
+∞
23.0
21
*
ZXA00, ,
ICD-O-3
+∞
23.0
21
*
J01EA01, ,
ATC
trimethoprim; systemic
+∞
23.0
21
*
M01AX17, ,
ATC
nimesulide; oral
+∞
23.0
21
*
LC2BE, ,
ICD-O-3
+∞
23.0
21
*
OAB43, ,
ICD-O-3
+∞
23.0
21
*
P01BA02, ,
ATC
hydroxychloroquine; oral
+∞
23.0
21
*
SPAT1223, ,
ICD-O-3
+∞
23.0
21
*
ZXA05, ,
ICD-O-3
+∞
21.8
20
*
L15, ,
ICD-O-3
+∞
21.8
20
*
SFC01, ,
ICD-O-3
+∞
21.8
20
*
EBA05, ,
ICD-O-3
+∞
21.8
20
*
R83, ,
ICD-O-3
+∞
21.8
20
*
K0382, ,
ICD-O-3
+∞
21.8
20
*
L03, ,
ICD-O-3
+∞
21.8
20
*
J01MA12, ,
ATC
levofloxacin; systemic
+∞
21.8
20
*
R060, ,
ICD-10 Finland
Dyspnoea
+∞
21.8
20
*
WX408, ,
ICD-O-3
+∞
21.8
20
*
J010, ,
ICD-O-3
+∞
21.8
20
*
Z718, ,
ICD-10 Finland
Other specified counselling
+∞
20.7
19
*
M03BC51, ,
ATC
orphenadrine, combinations; systemic
+∞
20.7
19
*
SPAT1325, ,
ICD-O-3
+∞
20.7
19
*
J05AB11, ,
ATC
valaciclovir; oral
+∞
20.7
19
*
J01DA06, ,
ATC
[U] cefuroxime
+∞
20.7
19
*
WZA90, ,
ICD-O-3
+∞
20.7
19
*
FM1EE, ,
ICD-O-3
+∞
20.7
19
*
R21, ,
ICD-O-3
+∞
20.7
19
*
TPH04, ,
ICD-O-3
+∞
20.7
19
*
203, ,
Kela drug reimbursment
Chronic asthma and similar chronic obstructive pulmonary diseases
+∞
20.7
19
*
R03BA02, ,
ATC
budesonide; inhalant
+∞
20.7
19
*
N02CC01, ,
ATC
sumatriptan; nasal, systemic, rectal
+∞
20.7
19
*
WX002, ,
ICD-O-3
+∞
20.7
19
*
CJE20, ,
ICD-O-3
+∞
20.7
19
*
SPAT1301, ,
ICD-O-3
+∞
19.5
18
*
U02, ,
ICD-O-3
+∞
19.5
18
*
R5180, ,
ICD-10 Finland
Headache
+∞
19.5
18
*
J459, ,
ICD-10 Finland
Asthma, unspecified
+∞
19.5
18
*
C08CA01, ,
ATC
amlodipine; oral
+∞
19.5
18
*
M03BC01, ,
ATC
orphenadrine (citrate); systemic
+∞
19.5
18
*
R074, ,
ICD-10 Finland
Chest pain, unspecified
+∞
19.5
18
*
E000001, ,
ATC
+∞
19.5
18
*
M255, ,
ICD-10 Finland
Pain in joint
+∞
19.5
18
*
C09CA06, ,
ATC
candesartan; oral
+∞
19.5
18
*
J01FA01, ,
ATC
erythromycin; systemic
+∞
19.5
18
*
C10AA05, ,
ATC
atorvastatin; oral
+∞
19.5
18
*
L01BA01, ,
ATC
methotrexate; systemic
+∞
19.5
18
*
R03AK06, ,
ATC
salmeterol and fluticasone; inhalant
+∞
19.5
18
*
NK4XE, ,
ICD-O-3
+∞
19.5
18
*
N06AX11, ,
ATC
mirtazapine; oral
+∞
19.5
18
*
A06AC01, ,
ATC
ispaghula (psylla seeds); oral
+∞
18.4
17
*
D07CA01, ,
ATC
hydrocortisone and antibiotics; topical
+∞
18.4
17
*
K045, ,
ICD-O-3
+∞
18.4
17
*
L04AX01, ,
ATC
azathioprine; systemic
+∞
18.4
17
*
SPAT1153, ,
ICD-O-3
+∞
18.4
17
*
SPAT1310, ,
ICD-O-3
+∞
18.4
17
*
R06AX22, ,
ATC
ebastine; oral
+∞
18.4
17
*
N06AB04, ,
ATC
citalopram; systemic
+∞
17.3
16
*
R104, ,
ICD-O-3
+∞
17.3
16
*
R01AD58, ,
ATC
fluticasone, combinations; nasal
+∞
17.3
16
*
SDA04, ,
ICD-O-3
+∞
17.3
16
*
C01DA08, ,
ATC
isosorbide dinitrate; oral, oral aerosol, sublingual, transdermal
+∞
17.3
16
*
C09CA01, ,
ATC
losartan; oral
+∞
17.3
16
*
Z3226, ,
ICD-O-3
+∞
17.3
16
*
A03, ,
ICD-O-3
+∞
17.3
16
*
O800, ,
ICD-10 Finland
Spontaneous vertex delivery
+∞
17.3
16
*
R06AX13, ,
ATC
loratadine; oral
+∞
17.3
16
*
TQX10, ,
ICD-O-3
+∞
17.3
16
*
SPAT1283, ,
ICD-O-3
+∞
17.3
16
*
SPAT1312, ,
ICD-O-3
+∞
17.3
16
*
Z718, ,
ICD-O-3
+∞
17.3
16
*
C03CA01, ,
ATC
furosemide; systemic
+∞
17.3
16
*
G473, ,
ICD-10 Finland
Sleep apnoea
+∞
17.3
16
*
X59, ,
ICD-10 Finland
Exposure to unspecified factor
+∞
17.3
16
*
SPAT1253, ,
ICD-O-3
+∞
17.3
16
*
WW200, ,
ICD-O-3
+∞
17.3
16
*
FM1AE, ,
ICD-O-3
+∞
16.2
15
*
A46, ,
ICD-10 Finland
Erysipelas
+∞
16.2
15
*
R103, ,
ICD-10 Finland
Pain localized to other parts of lower abdomen
+∞
16.2
15
*
Z039, ,
ICD-10 Finland
Observation for suspected disease or condition, unspecified
+∞
16.2
15
*
L28, ,
ICD-O-3
+∞
16.2
15
*
L309, ,
ICD-10 Finland
Dermatitis, unspecified
+∞
16.2
15
*
SDE02, ,
ICD-O-3
+∞
16.2
15
*
WX320, ,
ICD-O-3
+∞
16.2
15
*
R509, ,
ICD-10 Finland
Fever, unspecified
+∞
16.2
15
*
Z760, ,
ICD-O-3
+∞
16.2
15
*
Z712, ,
ICD-O-3
+∞
16.2
15
*
NG1AA, ,
ICD-O-3
+∞
16.2
15
*
J01AA07, ,
ATC
tetracycline; systemic
+∞
16.2
15
*
H251, ,
ICD-10 Finland
Senile nuclear cataract
+∞
16.2
15
*
PH2AE, ,
ICD-O-3
+∞
16.2
15
*
R03BA01, ,
ATC
beclometasone; inhalant
+∞
16.2
15
*
SFA40, ,
ICD-O-3
+∞
16.2
15
*
SDE03, ,
ICD-O-3
+∞
16.2
15
*
ZX120, ,
ICD-O-3
+∞
16.2
15
*
K0364, ,
ICD-O-3
+∞
15.0
14
*
WX402, ,
ICD-O-3
+∞
15.0
14
*
WX404, ,
ICD-O-3
+∞
15.0
14
*
Z010, ,
ICD-10 Finland
Examination of eyes and vision
+∞
15.0
14
*
R03AK07, ,
ATC
formoterol and budesonide; inhalant
+∞
15.0
14
*
ZY020, ,
ICD-O-3
+∞
15.0
14
*
R02, ,
ICD-O-3
+∞
15.0
14
*
N02AA05, ,
ATC
oxycodone; systemic
+∞
15.0
14
*
C07AA05, ,
ATC
propranolol; systemic
+∞
15.0
14
*
Z048, ,
ICD-10 Finland
Examination and observation for other specified reasons
+∞
15.0
14
*
D07AD01, ,
ATC
clobetasol; topical
+∞
15.0
14
*
U072, ,
ICD-O-3
+∞
15.0
14
*
J069, ,
ICD-10 Finland
Acute upper respiratory infection, unspecified
+∞
15.0
14
*
D01BA02, ,
ATC
terbinafine; oral
+∞
15.0
14
*
N06AB10, ,
ATC
escitalopram; oral
+∞
15.0
14
*
K573, ,
ICD-10 Finland
Diverticular disease of large intestine without perforation or abscess
+∞
15.0
14
*
Z363, ,
ICD-10 Finland
Antenatal screening for malformations using ultrasound and other physical methods
+∞
15.0
14
*
M545, ,
ICD-10 Finland
Low back pain
+∞
15.0
14
*
R298, ,
ICD-10 Finland
Other and unspecified symptoms and signs involving the nervous and musculoskeletal systems
+∞
15.0
14
*
R01AD01, ,
ATC
beclometasone; nasal
+∞
15.0
14
*
G04CA02, ,
ATC
tamsulosin; oral
+∞
15.0
14
*
R5110, ,
ICD-O-3
+∞
15.0
14
*
R238, ,
ICD-O-3
+∞
15.0
14
*
J01EE02, ,
ATC
sulfadiazine and trimethoprim; systemic
+∞
15.0
14
*
U071, ,
ICD-O-3
+∞
15.0
14
*
ZXA10, ,
ICD-O-3
+∞
13.9
13
*
G01AA10, ,
ATC
clindamycin; vaginal
+∞
13.9
13
*
L01, ,
ICD-O-3
+∞
13.9
13
*
ND2AA, ,
ICD-O-3
+∞
13.9
13
*
J01MA14, ,
ATC
moxifloxacin; systemic
+∞
13.9
13
*
K85, ,
ICD-O-3
+∞
13.9
13
*
65000, ,
ICD-8 Finland
Delivery without mention of complication, Occipital presentation
+∞
13.9
13
*
E000002, ,
ATC
+∞
13.9
13
*
A02BA02, ,
ATC
ranitidine; systemic
+∞
13.9
13
*
D01AE16, ,
ATC
amorolfine; topical
+∞
13.9
13
*
A09, ,
ICD-O-3
+∞
13.9
13
*
J189, ,
ICD-10 Finland
Pneumonia, unspecified
+∞
13.9
13
*
J45, ,
ICD-O-3
+∞
13.9
13
*
N03AX12, ,
ATC
[U] gabapentin; oral
+∞
13.9
13
*
SPAT1230, ,
ICD-O-3
+∞
13.9
13
*
D07AA02, ,
ATC
hydrocortisone; topical
+∞
13.9
13
*
Z011, ,
ICD-10 Finland
Examination of ears and hearing
+∞
13.9
13
*
C10AA07, ,
ATC
rosuvastatin; oral
+∞
13.9
13
*
M01AG02, ,
ATC
tolfenamic acid; oral, rectal
+∞
13.9
13
*
Z017, ,
ICD-O-3
+∞
12.8
12
*
XCW99, ,
ICD-O-3
+∞
12.8
12
*
R03BB04, ,
ATC
tiotropium bromide; inhalant
+∞
12.8
12
*
R509, ,
ICD-O-3
+∞
12.8
12
*
R103, ,
ICD-O-3
+∞
12.8
12
*
H01, ,
ICD-O-3
+∞
12.8
12
*
NK6QA, ,
ICD-O-3
+∞
12.8
12
*
J02AC02, ,
ATC
itraconazole; systemic
+∞
12.8
12
*
WYA30, ,
ICD-O-3
+∞
12.8
12
*
ZXD20, ,
ICD-O-3
+∞
12.8
12
*
UGC12, ,
ICD-O-3
+∞
12.8
12
*
M05BA04, ,
ATC
alendronic acid; oral
+∞
12.8
12
*
L309, ,
ICD-O-3
+∞
12.8
12
*
D01AC20, ,
ATC
imidazoles/triazoles in combination with corticosteroids; topical
+∞
12.8
12
*
J209, ,
ICD-O-3
+∞
12.8
12
*
N06AX21, ,
ATC
duloxetine; oral
+∞
12.8
12
*
Z000, ,
ICD-10 Finland
General medical examination
+∞
12.8
12
*
XF400, ,
ICD-O-3
+∞
12.8
12
*
R53, ,
ICD-O-3
+∞
12.8
12
*
M01AX05, ,
ATC
glucosamine; oral
+∞
12.8
12
*
Z014, ,
ICD-10 Finland
Gynaecological examination (general)(routine)
+∞
12.8
12
*
DMB20, ,
ICD-O-3
+∞
12.8
12
*
OAA65, ,
ICD-O-3
+∞
12.8
12
*
SGA01, ,
ICD-O-3
+∞
11.7
11
*
A07AA02, ,
ATC
nystatin; oral
+∞
11.7
11
*
D11, ,
ICD-O-3
+∞
11.7
11
*
104, ,
Kela drug reimbursment
Thyroid insufficiency
+∞
11.7
11
*
Z015, ,
ICD-10 Finland
Diagnostic skin and sensitization tests
+∞
11.7
11
*
OAA67, ,
ICD-O-3
+∞
11.7
11
*
N01, ,
ICD-O-3
+∞
11.7
11
*
FN1AC, ,
ICD-O-3
+∞
11.7
11
*
MA2HE, ,
ICD-O-3
+∞
11.7
11
*
H29, ,
ICD-O-3
+∞
11.7
11
*
R03AC03, ,
ATC
terbutaline; inhalant
+∞
11.7
11
*
XQ800, ,
ICD-O-3
+∞
11.7
11
*
ZXE20, ,
ICD-O-3
+∞
11.7
11
*
SHB00, ,
ICD-O-3
+∞
11.7
11
*
SPAT1148, ,
ICD-O-3
+∞
11.7
11
*
S21, ,
ICD-O-3
+∞
11.7
11
*
SPAT1262, ,
ICD-O-3
+∞
11.7
11
*
J320, ,
ICD-10 Finland
Chronic maxillary sinusitis
+∞
11.7
11
*
G03DC02, ,
ATC
norethisterone; oral
+∞
11.7
11
*
UJF30, ,
ICD-O-3
+∞
11.7
11
*
AA1CG, ,
ICD-O-3
+∞
11.7
11
*
H610, ,
ICD-10 Finland
Perichondritis of external ear
+∞
11.7
11
*
6500B, ,
ICD-9 Finland
Delivery in a completely normal case[PARTUS SINE COMPLICATIONE]
+∞
11.7
11
*
N02AE01, ,
ATC
buprenorphine; parenteral, sublingual, transdermal
+∞
11.7
11
*
R5180, ,
ICD-O-3
+∞
11.7
11
*
G442, ,
ICD-10 Finland
Tension-type headache
+∞
11.7
11
*
R96, ,
ICD-O-3
+∞
11.7
11
*
N05AH04, ,
ATC
quetiapine; oral
+∞
11.7
11
*
D01, ,
ICD-O-3
+∞
11.7
11
*
R06AX26, ,
ATC
fexofenadine; oral
+∞
11.7
11
*
M706, ,
ICD-O-3
+∞
11.7
11
*
M751, ,
ICD-O-3
+∞
11.7
11
*
U01, ,
ICD-O-3
+∞
11.7
11
*
A97, ,
ICD-O-3
+∞
11.7
11
*
H200, ,
ICD-10 Finland
Acute and subacute iridocyclitis
+∞
11.7
11
*
SPAT1324, ,
ICD-O-3
+∞
11.7
11
*
D07BB04, ,
ATC
hydrocortisone butyrate and antiseptics; topical
+∞
11.7
11
*
SAD01, ,
ICD-O-3
+∞
11.7
11
*
H02AB04, ,
ATC
methylprednisolone; systemic
+∞
11.7
11
*
K0530, ,
ICD-O-3
+∞
11.7
11
*
R060, ,
ICD-O-3
+∞
10.6
10
*
G03DB01, ,
ATC
dydrogesterone; oral
+∞
10.6
10
*
CK2X4, ,
ICD-O-3
+∞
10.6
10
*
Z024, ,
ICD-O-3
+∞
10.6
10
*
WX700, ,
ICD-O-3
+∞
10.6
10
*
N300, ,
ICD-O-3
+∞
10.6
10
*
103, ,
Kela drug reimbursment
Diabetes, insulin-treated
+∞
10.6
10
*
JN3AE, ,
ICD-O-3
+∞
10.6
10
*
MA1AE, ,
ICD-O-3
+∞
10.6
10
*
A46, ,
ICD-O-3
+∞
10.6
10
*
J01MA01, ,
ATC
ofloxacin; systemic
+∞
10.6
10
*
TPH07, ,
ICD-O-3
+∞
10.6
10
*
R42, ,
ICD-O-3
+∞
10.6
10
*
A04, ,
ICD-O-3
+∞
10.6
10
*
SPAT1216, ,
ICD-O-3
+∞
10.6
10
*
VALMI, ,
ICD-O-3
+∞
10.6
10
*
F29, ,
ICD-O-3
+∞
10.6
10
*
R074, ,
ICD-O-3
+∞
10.6
10
*
N30, ,
ICD-O-3
+∞
10.6
10
*
J01FA15, ,
ATC
telithromycin; oral
+∞
10.6
10
*
TNX10, ,
ICD-O-3
+∞
10.6
10
*
K044, ,
ICD-O-3
+∞
10.6
10
*
R06AE09, ,
ATC
levocetirizine; oral
+∞
10.6
10
*
DFF00, ,
ICD-O-3
+∞
10.6
10
*
I251, ,
ICD-10 Finland
Atherosclerotic heart disease
+∞
10.6
10
*
N951, ,
ICD-O-3
+∞
10.6
10
*
R53, ,
ICD-10 Finland
Malaise and fatigue
+∞
10.6
10
*
G560, ,
ICD-10 Finland
Carpal tunnel syndrome
+∞
10.6
10
*
WZC30, ,
ICD-O-3
+∞
10.6
10
*
EBA10, ,
ICD-O-3
+∞
10.6
10
*
G03AC03, ,
ATC
levonorgestrel; oral, implant
+∞
10.6
10
*
SPAT1308, ,
ICD-O-3
+∞
10.6
10
*
OAB48, ,
ICD-O-3
+∞
10.6
10
*
W00, ,
ICD-10 Finland
Fall on same level involving ice and snow
+∞
10.6
10
*
L88, ,
ICD-O-3
+∞
10.6
10
*
M01AH01, ,
ATC
celecoxib; oral
+∞
10.6
10
*
J01AA04, ,
ATC
lymecycline; systemic
+∞
10.6
10
*
215, ,
Kela drug reimbursment
Diabetes, non-insulin-treated
+∞
10.6
10
*
Z004, ,
ICD-10 Finland
General psychiatric examination, not elsewhere classified
+∞
10.6
10
*
A10BA02, ,
ATC
metformin; oral
+∞
10.6
10
*
L14, ,
ICD-O-3
+∞
10.6
10
*
C01CA24, ,
ATC
epinephrine; parenteral
+∞
10.6
10
*
J010, ,
ICD-10 Finland
Acute maxillary sinusitis
+∞
10.6
10
*
X58, ,
ICD-10 Finland
Exposure to other specified factors
+∞
10.6
10
*
M01AC01, ,
ATC
piroxicam; systemic, rectal
+∞
10.6
10
*
SFA00, ,
ICD-O-3
+∞
10.6
10
*
H0410, ,
ICD-10 Finland
Dry eye syndrome
+∞
10.6
10
*
XCK10, ,
ICD-O-3
+∞
10.6
10
*
J01MA06, ,
ATC
norfloxacin; oral
+∞
10.6
10
*
R529, ,
ICD-O-3
+∞
10.6
10
*
D07CC01, ,
ATC
betamethasone and antibiotics; topical
+∞
10.6
10
*
WX602, ,
ICD-O-3
+∞
9.6
9
*
SHA01, ,
ICD-O-3
+∞
9.6
9
*
CK2S4, ,
ICD-O-3
+∞
9.6
9
*
GD1UA, ,
ICD-O-3
+∞
9.6
9
*
D07BA04, ,
ATC
hydrocortisone and antiseptics; topical
+∞
9.6
9
*
K020, ,
ICD-O-3
+∞
9.6
9
*
R101, ,
ICD-O-3
+∞
9.6
9
*
Z0389, ,
ICD-10 Finland
Observation for other suspected diseases and conditions
+∞
9.6
9
*
R01AD05, ,
ATC
budesonide; nasal
+∞
9.6
9
*
N06AB06, ,
ATC
sertraline; oral
+∞
9.6
9
*
K210, ,
ICD-10 Finland
Gastro-oesophageal reflux disease with oesophagitis
+∞
9.6
9
*
N390, ,
ICD-10 Finland
Urinary tract infection, site not specified
+∞
9.6
9
*
L12, ,
ICD-O-3
+∞
9.6
9
*
J20, ,
ICD-O-3
+∞
9.6
9
*
L02, ,
ICD-O-3
+∞
9.6
9
*
H02, ,
ICD-O-3
+∞
9.6
9
*
K80, ,
ICD-O-3
+∞
9.6
9
*
UDH02, ,
ICD-O-3
+∞
9.6
9
*
JN1AE, ,
ICD-O-3
+∞
9.6
9
*
S01AA01, ,
ATC
chloramphenicol; ophthalmic
+∞
9.6
9
*
H60, ,
ICD-O-3
+∞
9.6
9
*
K802, ,
ICD-10 Finland
Calculus of gallbladder without cholecystitis
+∞
9.6
9
*
NA1BG, ,
ICD-O-3
+∞
9.6
9
*
C07AB02, ,
ATC
metoprolol; systemic
+∞
9.6
9
*
B01AA03, ,
ATC
warfarin; systemic
+∞
9.6
9
*
M01AH02, ,
ATC
rofecoxib; oral
+∞
9.6
9
*
NH3AA, ,
ICD-O-3
+∞
9.6
9
*
J01CF05, ,
ATC
flucloxacillin; systemic
+∞
9.6
9
*
K040, ,
ICD-O-3
+∞
9.6
9
*
L04AA13, ,
ATC
[U] leflunomide
+∞
9.6
9
*
M511, ,
ICD-10 Finland
Lumbar and other intervertebral disc disorders with radiculopathy
+∞
9.6
9
*
D07BC01, ,
ATC
betamethasone and antiseptics; topical
+∞
8.5
8
*
N06CA01, ,
ATC
amitriptyline and psycholeptics; systemic
+∞
8.5
8
*
H601, ,
ICD-O-3
+∞
8.5
8
*
GD1BD, ,
ICD-O-3
+∞
8.5
8
*
LX1AE, ,
ICD-O-3
+∞
8.5
8
*
H609, ,
ICD-10 Finland
Otitis externa, unspecified
+∞
8.5
8
*
D649, ,
ICD-10 Finland
Anaemia, unspecified
+∞
8.5
8
*
TKC20, ,
ICD-O-3
+∞
8.5
8
*
WZC10, ,
ICD-O-3
+∞
8.5
8
*
ZYC01, ,
ICD-O-3
+∞
8.5
8
*
K0380, ,
ICD-O-3
+∞
8.5
8
*
O049, ,
ICD-10 Finland
Medical abortion, complete or unspecified, without complication
+∞
8.5
8
*
A04AA01, ,
ATC
ondansetron; systemic, rectal
+∞
8.5
8
*
L82, ,
ICD-O-3
+∞
8.5
8
*
205, ,
Kela drug reimbursment
Chronic hypertension
+∞
8.5
8
*
XKD00, ,
ICD-O-3
+∞
8.5
8
*
N832, ,
ICD-10 Finland
Other and unspecified ovarian cysts
+∞
8.5
8
*
L29, ,
ICD-O-3
+∞
8.5
8
*
N06AX16, ,
ATC
venlafaxine; oral
+∞
8.5
8
*
J459, ,
ICD-O-3
+∞
8.5
8
*
J209, ,
ICD-10 Finland
Acute bronchitis, unspecified
+∞
8.5
8
*
A44, ,
ICD-O-3
+∞
8.5
8
*
R101, ,
ICD-10 Finland
Pain localized to upper abdomen
+∞
8.5
8
*
R42, ,
ICD-10 Finland
Dizziness and giddiness
+∞
8.5
8
*
H109, ,
ICD-O-3
+∞
8.5
8
*
E7801, ,
ICD-10 Finland
Pure hypercholesterolaemia
+∞
8.5
8
*
SGA02, ,
ICD-O-3
+∞
8.5
8
*
A01, ,
ICD-O-3
+∞
8.5
8
*
M791, ,
ICD-O-3
+∞
8.5
8
*
UDC00, ,
ICD-O-3
+∞
8.5
8
*
G01AF05, ,
ATC
econazole; vaginal
+∞
8.5
8
*
W19, ,
ICD-10 Finland
Unspecified fall
+∞
8.5
8
*
JKA21, ,
ICD-O-3
+∞
8.5
8
*
N05CF02, ,
ATC
zolpidem; oral
+∞
8.5
8
*
J189, ,
ICD-O-3
+∞
8.5
8
*
D07AB08, ,
ATC
desonide; topical
+∞
8.5
8
*
M531, ,
ICD-O-3
+∞
8.5
8
*
S29, ,
ICD-O-3
+∞
8.5
8
*
B02AA02, ,
ATC
tranexamic acid; systemic
+∞
8.5
8
*
MA2AE, ,
ICD-O-3
+∞
8.5
8
*
C09AA02, ,
ATC
enalapril; systemic
+∞
8.5
8
*
T814, ,
ICD-10 Finland
Infection following a procedure, not elsewhere classified
+∞
8.5
8
*
NA3BG, ,
ICD-O-3
+∞
8.5
8
*
G02BA03, ,
ATC
plastic IUD with progestogen
+∞
8.5
8
*
R03AK10, ,
ATC
vilanterol and fluticasone furoate; inhalant
+∞
8.5
8
*
T90, ,
ICD-O-3
+∞
8.5
8
*
E119, ,
ICD-10 Finland
Type 2 diabetes mellitus, without complications
+∞
8.5
8
*
Z3229, ,
ICD-O-3
+∞
8.5
8
*
SGA04, ,
ICD-O-3
+∞
8.5
8
*
EB1VA, ,
ICD-O-3
+∞
8.5
8
*
K0365, ,
ICD-O-3
+∞
8.5
8
*
M02AA15, ,
ATC
diclofenac; topical
+∞
8.5
8
*
K0510, ,
ICD-O-3
+∞
8.5
8
*
L16, ,
ICD-O-3
+∞
8.5
8
*
Z302, ,
ICD-10 Finland
Sterilization
+∞
8.5
8
*
WX100, ,
ICD-O-3
+∞
8.5
8
*
A29, ,
ICD-O-3
+∞
8.5
8
*
C05AA08, ,
ATC
fluocortolone; rectal, topical
+∞
8.5
8
*
F419, ,
ICD-10 Finland
Anxiety disorder, unspecified
+∞
8.5
8
*
R065, ,
ICD-10 Finland
Mouth breathing
+∞
8.5
8
*
N393, ,
ICD-10 Finland
Stress incontinence
+∞
8.5
8
*
N06AB03, ,
ATC
fluoxetine; oral
+∞
8.5
8
*
GD1QA, ,
ICD-O-3
+∞
8.5
8
*
C03DA01, ,
ATC
spironolactone; oral
+∞
7.4
7
*
NA3AA, ,
ICD-O-3
+∞
7.4
7
*
M17, ,
ICD-O-3
+∞
7.4
7
*
R5140, ,
ICD-O-3
+∞
7.4
7
*
K30, ,
ICD-O-3
+∞
7.4
7
*
J22, ,
ICD-O-3
+∞
7.4
7
*
Z014, ,
ICD-O-3
+∞
7.4
7
*
NGD05, ,
ICD-O-3
+∞
7.4
7
*
J451, ,
ICD-10 Finland
Nonallergic asthma
+∞
7.4
7
*
R21, ,
ICD-10 Finland
Rash and other nonspecific skin eruption
+∞
7.4
7
*
A07EC02, ,
ATC
mesalazine; oral, rectal
+∞
7.4
7
*
R03BC03, ,
ATC
nedocromil; inhalant
+∞
7.4
7
*
A11, ,
ICD-O-3
+∞
7.4
7
*
D06AX01, ,
ATC
fusidic acid; topical
+∞
7.4
7
*
GD1AD, ,
ICD-O-3
+∞
7.4
7
*
M54, ,
ICD-O-3
+∞
7.4
7
*
SPAT1156, ,
ICD-O-3
+∞
7.4
7
*
HA1AE, ,
ICD-O-3
+∞
7.4
7
*
SFC92, ,
ICD-O-3
+∞
7.4
7
*
TQW40, ,
ICD-O-3
+∞
7.4
7
*
G43, ,
ICD-O-3
+∞
7.4
7
*
WX105, ,
ICD-O-3
+∞
7.4
7
*
L04, ,
ICD-O-3
+∞
7.4
7
*
SGC00, ,
ICD-O-3
+∞
7.4
7
*
XLD00, ,
ICD-O-3
+∞
7.4
7
*
J342, ,
ICD-10 Finland
Deviated nasal septum
+∞
7.4
7
*
M171, ,
ICD-10 Finland
Other primary gonarthrosis
+∞
7.4
7
*
Z033, ,
ICD-10 Finland
Observation for suspected nervous system disorder
+∞
7.4
7
*
M722, ,
ICD-10 Finland
Plantar fascial fibromatosis
+∞
7.4
7
*
C01DA14, ,
ATC
isosorbide mononitrate; oral
+∞
7.4
7
*
C10AX09, ,
ATC
ezetimibe; oral
+∞
7.4
7
*
Z3232, ,
ICD-O-3
+∞
7.4
7
*
50099, ,
ICD-8 Finland
Hypertrophy of tonsils and adenoids
+∞
7.4
7
*
TLC00, ,
ICD-O-3
+∞
7.4
7
*
F510, ,
ICD-O-3
+∞
7.4
7
*
G01AF01, ,
ATC
metronidazole; vaginal
+∞
7.4
7
*
H903, ,
ICD-10 Finland
Sensorineural hearing loss, bilateral
+∞
7.4
7
*
SXA20, ,
ICD-O-3
+∞
7.4
7
*
FB1BD, ,
ICD-O-3
+∞
7.4
7
*
Z2446, ,
ICD-O-3
+∞
7.4
7
*
H160, ,
ICD-10 Finland
Corneal ulcer
+∞
7.4
7
*
HA1AA, ,
ICD-O-3
+∞
7.4
7
*
F412, ,
ICD-O-3
+∞
7.4
7
*
D509, ,
ICD-10 Finland
Iron deficiency anaemia, unspecified
+∞
7.4
7
*
Z03, ,
ICD-O-3
+∞
7.4
7
*
LC2AE, ,
ICD-O-3
+∞
7.4
7
*
206, ,
Kela drug reimbursment
Chronic coronary artery disease and dyslipidaemia associated with chronic coronary artery disease
+∞
7.4
7
*
JN4BD, ,
ICD-O-3
+∞
7.4
7
*
Z961, ,
ICD-10 Finland
Presence of intraocular lens
+∞
7.4
7
*
B01AB10, ,
ATC
tinzaparin; parenteral
+∞
7.4
7
*
SPAT1254, ,
ICD-O-3
+∞
7.4
7
*
S15, ,
ICD-O-3
+∞
7.4
7
*
WX006, ,
ICD-O-3
+∞
7.4
7
*
O244, ,
ICD-10 Finland
Diabetes mellitus arising in pregnancy
+∞
7.4
7
*
H920, ,
ICD-O-3
+∞
7.4
7
*
Z000, ,
ICD-O-3
+∞
7.4
7
*
Z712, ,
ICD-10 Finland
Person consulting for explanation of investigation findings
+∞
7.4
7
*
S01, ,
ICD-O-3
+∞
7.4
7
*
R11, ,
ICD-10 Finland
Nausea and vomiting
+∞
7.4
7
*
A09, ,
ICD-10 Finland
Other gastroenteritis and colitis of infectious and unspecified origin
+∞
7.4
7
*
S01ED51, ,
ATC
timolol, combinations; ophthalmic
+∞
7.4
7
*
A28, ,
ICD-O-3
+∞
7.4
7
*
H0410, ,
ICD-O-3
+∞
7.4
7
*
H81, ,
ICD-O-3
+∞
7.4
7
*
R03AL01, ,
ATC
fenoterol and ipratropium bromide; inhalant
+∞
7.4
7
*
R13, ,
ICD-10 Finland
Dysphagia
+∞
7.4
7
*
A01AB09, ,
ATC
miconazole; local oral
+∞
7.4
7
*
R062, ,
ICD-10 Finland
Wheezing
+∞
7.4
7
*
R2130, ,
ICD-O-3
+∞
7.4
7
*
EP1AE, ,
ICD-O-3
+∞
7.4
7
*
C03EA01, ,
ATC
hydrochlorothiazide and potassium-sparing agents; oral
+∞
7.4
7
*
D07XC01, ,
ATC
betamethasone; topical
+∞
7.4
7
*
Z258, ,
ICD-O-3
+∞
7.4
7
*
N17, ,
ICD-O-3
+∞
7.4
7
*
B01AB04, ,
ATC
dalteparin; parenteral
+∞
6.3
6
*
R03AC13, ,
ATC
formoterol; inhalant
+∞
6.3
6
*
K083, ,
ICD-O-3
+∞
6.3
6
*
C09AA05, ,
ATC
ramipril; oral
+∞
6.3
6
*
K041, ,
ICD-O-3
+∞
6.3
6
*
XCK00, ,
ICD-O-3
+∞
6.3
6
*
E11, ,
ICD-O-3
+∞
6.3
6
*
NGB20, ,
ICD-O-3
+∞
6.3
6
*
L04AA06, ,
ATC
mycophenolic acid; systemic
+∞
6.3
6
*
E118, ,
ICD-10 Finland
Type 2 diabetes mellitus, with unspecified complications
+∞
6.3
6
*
XPX99, ,
ICD-O-3
+∞
6.3
6
*
NG1BG, ,
ICD-O-3
+∞
6.3
6
*
I639, ,
ICD-10 Finland
Cerebral infarction, unspecified
+∞
6.3
6
*
H531, ,
ICD-10 Finland
Subjective visual disturbances
+∞
6.3
6
*
R2110, ,
ICD-O-3
+∞
6.3
6
*
SGB10, ,
ICD-O-3
+∞
6.3
6
*
H438, ,
ICD-10 Finland
Other disorders of vitreous body
+∞
6.3
6
*
SPAT1028, ,
ICD-O-3
+∞
6.3
6
*
L20, ,
ICD-O-3
+∞
6.3
6
*
NE1AA, ,
ICD-O-3
+∞
6.3
6
*
F03, ,
ICD-O-3
+∞
6.3
6
*
JN3BD, ,
ICD-O-3
+∞
6.3
6
*
N02BF01, ,
ATC
gabapentin; oral
+∞
6.3
6
*
U71, ,
ICD-O-3
+∞
6.3
6
*
JN4AD, ,
ICD-O-3
+∞
6.3
6
*
D02, ,
ICD-O-3
+∞
6.3
6
*
L04AD01, ,
ATC
ciclosporin; systemic
+∞
6.3
6
*
M359, ,
ICD-10 Finland
Systemic involvement of connective tissue, unspecified
+∞
6.3
6
*
S01BA01, ,
ATC
dexamethasone; ophthalmic
+∞
6.3
6
*
K0880, ,
ICD-O-3
+∞
6.3
6
*
L05, ,
ICD-O-3
+∞
6.3
6
*
F458, ,
ICD-O-3
+∞
6.3
6
*
G430, ,
ICD-10 Finland
Migraine without aura [common migraine]
+∞
6.3
6
*
SAB01, ,
ICD-O-3
+∞
6.3
6
*
E03, ,
ICD-O-3
+∞
6.3
6
*
ACC51, ,
ICD-O-3
+∞
6.3
6
*
M139, ,
ICD-10 Finland
Arthritis, unspecified
+∞
6.3
6
*
QAE10, ,
ICD-O-3
+∞
6.3
6
*
MCA10, ,
ICD-O-3
+∞
6.3
6
*
M544, ,
ICD-O-3
+∞
6.3
6
*
GD1PA, ,
ICD-O-3
+∞
6.3
6
*
G03FA12, ,
ATC
medroxyprogesterone and estrogen; systemic
+∞
6.3
6
*
C01DA02, ,
ATC
glyceryl trinitrate; oral, oral aerosol, sublingual, transdermal
+∞
6.3
6
*
A05, ,
ICD-O-3
+∞
6.3
6
*
A499, ,
ICD-10 Finland
Bacterial infection, unspecified
+∞
6.3
6
*
M179, ,
ICD-O-3
+∞
6.3
6
*
H264, ,
ICD-10 Finland
After-cataract
+∞
6.3
6
*
A06AD11, ,
ATC
lactulose; oral
+∞
6.3
6
*
L04AA01, ,
ATC
[U] ciclosporin
+∞
6.3
6
*
G04BD08, ,
ATC
solifenacin; oral
+∞
6.3
6
*
XF404, ,
ICD-O-3
+∞
6.3
6
*
A99, ,
ICD-O-3
+∞
6.3
6
*
Z315, ,
ICD-10 Finland
Genetic counselling
+∞
6.3
6
*
R29, ,
ICD-O-3
+∞
6.3
6
*
SPAT1260, ,
ICD-O-3
+∞
6.3
6
*
SGB30, ,
ICD-O-3
+∞
6.3
6
*
R01BA51, ,
ATC
phenylpropanolamine, combinations; oral
+∞
6.3
6
*
P03, ,
ICD-O-3
+∞
6.3
6
*
K219, ,
ICD-10 Finland
Gastro-oesophageal reflux disease without oesophagitis
+∞
6.3
6
*
OAB91, ,
ICD-O-3
+∞
6.3
6
*
A10BH01, ,
ATC
sitagliptin; oral
+∞
6.3
6
*
R75, ,
ICD-O-3
+∞
6.3
6
*
H100, ,
ICD-O-3
+∞
6.3
6
*
DM1QA, ,
ICD-O-3
+∞
6.3
6
*
M949, ,
ICD-10 Finland
Disorder of cartilage, unspecified
+∞
6.3
6
*
EB4VA, ,
ICD-O-3
+∞
6.3
6
*
H201, ,
ICD-10 Finland
Chronic iridocyclitis
+∞
6.3
6
*
RD211, ,
ICD-O-3
+∞
6.3
6
*
M02AA10, ,
ATC
ketoprofen; topical
+∞
6.3
6
*
NGF25, ,
ICD-O-3
+∞
6.3
6
*
R55, ,
ICD-10 Finland
Syncope and collapse
+∞
6.3
6
*
SPAT1097, ,
ICD-O-3
+∞
6.3
6
*
R06AX12, ,
ATC
terfenadine; oral
+∞
6.3
6
*
S76, ,
ICD-O-3
+∞
6.3
6
*
S82, ,
ICD-O-3
+∞
6.3
6
*
R91, ,
ICD-10 Finland
Abnormal findings on diagnostic imaging of lung
+∞
6.3
6
*
H620, A46,
ICD-10 Finland
Otitis externa in erysipelas
+∞
6.3
6
*
SPAT1240, ,
ICD-O-3
+∞
6.3
6
*
J310, ,
ICD-10 Finland
Chronic rhinitis
+∞
6.3
6
*
SBB10, ,
ICD-O-3
+∞
6.3
6
*
S934, ,
ICD-10 Finland
Sprain and strain of ankle
+∞
6.3
6
*
-44, ,
ICD-O-3
+∞
6.3
6
*
N03AG01, ,
ATC
valproic acid; systemic, rectal
+∞
6.3
6
*
R03BA08, ,
ATC
ciclesonide; inhalant
+∞
6.3
6
*
G431, ,
ICD-10 Finland
Migraine with aura [classical migraine]
+∞
6.3
6
*
D06, ,
ICD-O-3
+∞
6.3
6
*
OAB42, ,
ICD-O-3
+∞
6.3
6
*
U07, ,
ICD-O-3
+∞
6.3
6
*
B03BA03, ,
ATC
hydroxocobalamin; parenteral
+∞
6.3
6
*
SXB00, ,
ICD-O-3
+∞
6.3
6
*
N10, ,
ICD-10 Finland
Acute tubulo-interstitial nephritis
+∞
6.3
6
*
TDM10, ,
ICD-O-3
+∞
6.3
6
*
NB1AA, ,
ICD-O-3
+∞
6.3
6
*
S0251, ,
ICD-O-3
+∞
6.3
6
*
R01AD11, ,
ATC
triamcinolone; nasal
+∞
6.3
6
*
SPAT1305, ,
ICD-O-3
+∞
6.3
6
*
G03DA02, ,
ATC
medroxyprogesterone; systemic
+∞
6.3
6
*
L089, ,
ICD-O-3
+∞
6.3
6
*
SPAT1360, ,
ICD-O-3
+∞
6.3
6
*
SPAT1250, ,
ICD-O-3
+∞
6.3
6
*
XF402, ,
ICD-O-3
+∞
6.3
6
*
LCA06, ,
ICD-O-3
+∞
6.3
6
*
SCA02, ,
ICD-O-3
+∞
6.3
6
*
WZA00, ,
ICD-O-3
+∞
6.3
6
*
G01AF04, ,
ATC
miconazole; vaginal
+∞
6.3
6
*
H811, ,
ICD-10 Finland
Benign paroxysmal vertigo
+∞
6.3
6
*
F430, ,
ICD-O-3
+∞
6.3
6
*
H023, ,
ICD-10 Finland
Blepharochalasis
+∞
6.3
6
*
M751, ,
ICD-10 Finland
Rotator cuff syndrome
+∞
6.3
6
*
K081, ,
ICD-O-3
+∞
6.3
6
*
N07CA01, ,
ATC
betahistine; oral
+∞
6.3
6
*
P06, ,
ICD-O-3
+∞
6.3
6
*
I350, ,
ICD-10 Finland
Aortic (valve) stenosis
+∞
6.3
6
*
J450, ,
ICD-10 Finland
Predominantly allergic asthma
+∞
6.3
6
*
EBA30, ,
ICD-O-3
+∞
6.3
6
*
O470, ,
ICD-10 Finland
False labour before 37 completed weeks of gestation
+∞
6.3
6
*
R07, ,
ICD-O-3
+∞
6.3
6
*
XF600, ,
ICD-O-3
+∞
6.3
6
*
E883A, ,
ICD-9 Finland
Fall into hole or other opening in surface
+∞
6.3
6
*
E039, ,
ICD-O-3
+∞
6.3
6
*
B01AC04, ,
ATC
clopidogrel; oral
+∞
6.3
6
*
R229, ,
ICD-O-3
+∞
6.3
6
*
H609, ,
ICD-O-3
+∞
6.3
6
*
N02CC04, ,
ATC
rizatriptan; oral
+∞
6.3
6
*
N06AA09, ,
ATC
amitriptyline; systemic
+∞
6.3
6
*
M232, ,
ICD-10 Finland
Derangement of meniscus due to old tear or injury
+∞
6.3
6
*
L11, ,
ICD-O-3
+∞
6.3
6
*
K449, ,
ICD-10 Finland
Diaphragmatic hernia without obstruction or gangrene
+∞
6.3
6
*
G473, ,
ICD-O-3
+∞
6.3
6
*
SPAT1033, ,
ICD-O-3
+∞
6.3
6
*
S01ED01, ,
ATC
timolol; ophthalmic
+∞
6.3
6
*
E039, ,
ICD-10 Finland
Hypothyroidism, unspecified
+∞
6.3
6
*
N62, ,
ICD-10 Finland
Hypertrophy of breast
+∞
6.3
6
*
UJF45, ,
ICD-O-3
+∞
6.3
6
*

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
43
106
7.34
18.73
1.8
1.3
342.50
469.23
titre
0.50
16
26
66
312
6.45
12.47
14.5
5.7
2.89
2.73
%
0.24
66
291
65
305
6.22
12.34
14.4
5.6
0.77
0.72
%
0.34
65
280
66
316
6.31
12.16
14.8
5.9
8.93
8.09
%
1.77
66
295
25
53
6.32
12.12
2.3
1.9
11.81
9.85
g/l
0.96
25
47
66
318
6.25
12.01
14.0
5.6
57.05
57.86
%
0.26
66
298
66
323
6.09
11.64
14.6
5.7
28.31
28.01
%
0.09
66
303
67
332
6.28
11.64
13.9
6.2
—
—
—
0
0
20
43
5.81
9.40
1.7
1.7
1.16
1.03
g/l
0.38
20
38
44
182
4.02
9.04
11.6
6.9
—
—
—
0
0
60
345
3.67
6.83
5.0
3.5
0.00
0.00
estimate
-0.00
12
78
60
347
3.63
6.73
6.5
4.8
0.00
0.00
estimate
-0.00
12
75
60
350
3.58
6.57
5.0
3.5
0.00
0.00
estimate
-0.00
12
71
75
534
5.19
6.54
9.7
3.9
10.73
10.16
mm/h
0.16
75
486
47
239
3.23
6.44
3.9
3.1
43.88
48.01
e6/l
0.05
33
171
71
472
4.49
6.14
8.1
3.6
—
—
—
0
0
16
33
5.75
5.81
1.2
1.2
—
—
—
0
0
40
197
2.99
5.62
2.8
2.6
70.92
27.68
e6/l
0.34
32
159
32
141
3.07
5.44
3.9
3.6
—
—
—
0
0
23
83
3.45
5.42
2.3
1.3
—
—
—
0
0
33
150
2.99
5.30
1.6
1.3
10.40
39.19
iu/ml
—
10
48
18
57
3.76
5.12
3.4
4.4
0.00
0.00
%
—
5
17
32
146
2.94
5.07
1.7
1.3
1.76
2.38
g/l
2.32
25
95
9
10
9.92
4.92
1.2
1.2
—
—
—
0
0
16
48
3.89
4.90
1.4
1.5
—
—
—
0
0
18
59
3.62
4.87
4.5
4.3
0.00
0.25
%
—
5
20
19
65
3.49
4.82
4.3
4.2
0.67
0.75
%
—
6
26
7
5
15.09
4.66
1.1
1.0
—
—
—
0
0
7
6
12.57
4.36
1.3
1.3
—
—
—
0
0
49
298
2.57
4.24
5.4
5.4
1.21
1.22
mmol/l
0.23
43
250
8
12
7.24
3.77
1.4
1.3
—
—
—
0
0
34
182
2.47
3.76
2.8
2.5
0.15
0.42
e6/l
1.20
29
141
29
147
2.50
3.58
1.3
1.3
1.12
9.04
u/ml
1.65
13
59
16
59
3.12
3.56
4.8
4.1
0.40
0.53
%
—
5
20
34
187
2.39
3.50
3.6
3.4
7.42
7.41
ph
—
5
37
8
14
6.19
3.43
1.3
1.4
—
—
—
0
0
35
197
2.34
3.41
3.9
2.2
—
—
—
0
0
26
128
2.50
3.39
6.2
4.5
—
—
—
0
0
20
88
2.68
3.25
1.2
1.5
—
—
—
0
0
7
13
5.77
2.93
1.4
1.8
—
—
—
0
0
19
86
2.57
2.91
1.6
1.4
—
—
—
0
0
28
153
2.25
2.85
2.6
1.7
0.49
1.32
mg/l
1.84
23
124
29
162
2.21
2.79
1.3
1.3
4.59
0.93
u/ml
—
9
45
22
110
2.36
2.73
1.5
1.5
—
—
—
0
0
11
36
3.36
2.68
1.3
1.1
—
—
—
0
0
59
441
2.17
2.59
5.7
3.7
—
34.57
—
0
7
9
26
3.75
2.57
8.2
8.5
23.67
24.30
mmol/l
—
9
26
19
92
2.38
2.52
1.1
1.3
—
—
—
0
0
14
59
2.65
2.45
2.1
1.3
—
—
—
0
0
26
146
2.14
2.43
2.5
2.1
10.42
5.51
e6/l
0.42
26
131
15
67
2.51
2.34
6.2
6.0
105.73
103.79
mmol/l
0.84
15
67
32
197
2.02
2.34
6.2
3.7
0.00
0.00
estimate
-0.00
12
73
7
18
4.14
2.30
3.4
3.1
—
—
—
0
0
18
89
2.31
2.27
1.7
2.0
—
—
—
0
0
29
178
1.97
2.11
2.8
2.4
—
—
—
0
0
11
44
2.73
2.11
7.6
5.7
—
—
—
0
0
41
283
1.89
2.10
3.8
3.5
35.77
36.26
g/l
0.24
41
267
8
28
3.05
1.92
1.8
2.4
0.56
0.73
%
—
8
28
8
29
2.94
1.84
2.8
2.8
128.13
133.48
g/l
—
8
29
15
75
2.22
1.83
2.9
1.7
22.27
25.11
%
0.40
15
64
9
36
2.68
1.80
6.9
4.3
23.89
24.50
mmol/l
—
9
36
41
295
1.77
1.76
23.2
10.0
1.32
1.15
inr
0.61
19
91
5
13
4.02
1.74
1.4
1.1
—
—
—
0
0
11
49
2.44
1.72
3.3
2.4
—
—
—
0
0
22
131
1.92
1.71
2.9
2.5
598.18
553.38
mosm/kgh2o
0.30
22
111
8
31
2.74
1.71
1.8
2.4
1.04
1.51
%
—
8
31
14
73
2.10
1.55
1.4
1.7
—
—
—
0
0
31
212
1.74
1.55
5.4
3.1
—
—
—
0
0
5
15
3.48
1.54
1.2
1.3
—
—
—
0
0
10
46
2.33
1.46
7.6
5.3
0.99
1.36
mmol/l
—
10
46
40
299
1.65
1.41
2.5
1.9
—
—
—
0
0
29
199
1.70
1.41
2.1
2.2
—
—
—
0
0
19
115
1.85
1.40
4.5
3.1
182.00
167.84
ng/l
—
8
79
11
55
2.15
1.34
1.2
1.2
45.87
143.88
iu/ml
—
6
20
40
302
1.63
1.34
4.3
2.6
123.45
101.56
ug/l
0.36
40
282
11
56
2.11
1.29
3.1
3.3
—
—
—
0
0
50
402
1.61
1.28
4.0
3.9
6.21
6.61
mmol/l
1.07
50
376
21
135
1.74
1.27
2.0
1.8
—
—
—
0
0
16
95
1.85
1.25
3.8
1.7
11.99
14.46
umol/l
0.88
16
85
8
39
2.16
1.19
1.8
1.3
—
—
—
0
0
32
238
1.56
1.10
2.0
1.9
92.21
95.78
pmol/l
0.17
20
128
33
249
1.54
1.06
4.4
3.7
17.57
45.94
ng/l
1.02
21
159
7
36
2.03
0.99
1.1
1.1
—
—
—
0
0
13
78
1.79
0.98
3.5
2.1
286.31
358.76
nmol/l
0.66
13
71
70
630
1.71
0.96
32.6
14.2
14.38
14.90
%
0.57
70
619
22
289
0.68
0.79
2.3
2.8
—
—
—
0
0
6
34
1.82
0.78
2.8
1.9
—
—
—
0
0
56
493
1.42
0.72
4.3
3.5
—
—
—
0
0
5
26
1.98
0.72
3.6
3.4
24.68
24.75
mmol/l
—
5
26
7
47
1.53
0.49
1.6
2.7
3.79
8.83
e9/l
—
7
40
78
749
1.69
0.48
18.1
10.9
—
—
—
0
0
11
77
1.49
0.48
1.0
1.3
—
—
—
0
0
5
31
1.65
0.44
1.2
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.6
—
24.96
—
0
17
16
195
0.78
0.33
3.0
3.7
3.17
8.31
mg/mmol
—
10
119
15
184
0.77
0.33
2.5
3.1
14.81
54.54
mg/l
—
9
121
7
54
1.32
0.31
2.3
1.4
—
—
—
0
0
7
56
1.27
0.30
1.1
1.1
—
—
—
0
0
11
138
0.77
0.28
1.7
1.7
474.82
483.59
pmol/l
0.05
11
119
9
75
1.22
0.26
3.3
2.7
6.87
7.88
umol/l
—
9
64
5
38
1.34
0.23
1.0
1.0
—
—
—
0
0
10
79
1.30
0.23
3.3
2.9
0.95
1.01
mmol/l
—
10
74
0
11
0.00
0.21
0.0
1.7
—
91.59
—
0
11
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
271.80
—
0
5
0
14
0.00
0.20
0.0
1.4
—
50.64
—
0
14
0
14
0.00
0.20
0.0
1.2
—
—
—
0
0
17
191
0.86
0.16
1.2
1.5
—
—
—
0
0
9
81
1.12
0.15
1.1
1.3
—
—
—
0
0
10
87
1.17
0.10
2.4
1.2
—
—
—
0
0
6
55
1.10
0.09
1.2
2.0
—
—
—
0
0
6
55
1.10
0.09
1.3
3.8
—
—
—
0
0
5
62
0.79
0.08
1.0
1.8
—
—
—
0
0
20
189
1.08
0.05
5.0
3.6
—
—
—
0
0
56
549
1.06
0.04
5.9
4.3
14.75
14.62
pmol/l
0.13
56
513
17
177
0.95
0.01
6.4
5.1
1.93
1.82
ug/l
0.06
17
161
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
6
66
0.90
-0.00
14.0
2.8
—
—
—
0
0
6
67
0.89
-0.00
2.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
22.23
—
0
9
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
70
700
1.00
-0.00
3.7
4.5
1.53
1.50
mmol/l
0.20
70
647
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
17.3
—
1439.14
—
0
7
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.7
—
5.52
—
0
6
0
7
0.00
-0.00
0.0
14.4
—
877.57
—
0
7
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint M13_RELAPSPOLYCHONDR and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_RELAPSPOLYCHONDR.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: M13_RELAPSPOLYCHONDR – Relapsing polychondritis

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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