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This is a non-core endpoint: only basic statistics are computed.

Agent resistant to other and unspecified antibiotics

U22_AGENT_RESISTANT_OTHER_UNSPE_ANTIBI

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 U89
  • Cause of death: ICD-10 U89

2 out of 7 registries used, show all original rules.

6

4. Check minimum number of events

None

6

5. Include endpoints

None

6

6. Filter based on genotype QC (FinnGen only)

6

Control definitions (FinnGen only)

Control exclude
U22_BACTERIAL_AGENTS_RESISTANT_ANTIBI

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
U8

Case counts by codes

FinnGen case counts by registry codes:

Not enough data for upset plot.

Not enough data for upset table.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 23 19 -
Only index persons 23 19 -
Unadjusted period prevalence (%)
Whole population 0.00 0.00 -
Only index persons 0.00 0.00 -
Median age at first event (years)
Whole population - 53.40 -
Only index persons 51.61 53.40 -

-FinnGen-

Key figures

All Female Male
Number of individuals 6 - -
Unadjusted period prevalence (%) 0.00 - -
Median age at first event (years) 53.50 - -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
6
19
+∞
2.71
1.8
2.9
—
—
—
0
0
6
35
+∞
1.12
6.5
3.9
—
—
—
0
0
6
45
+∞
0.49
48.5
14.6
40.00
16.26
mg/l
—
6
38
6
48
+∞
0.23
51.3
13.7
139.67
140.31
mmol/l
—
6
48
6
48
+∞
0.23
53.5
14.0
3.87
3.95
mmol/l
—
6
48
6
51
+∞
0.23
44.0
11.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.6
—
—
—
0
0
6
52
+∞
-0.00
53.0
15.3
65.83
78.52
umol/l
—
6
52
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint U22_AGENT_RESISTANT_OTHER_UNSPE_ANTIBI and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have U22_AGENT_RESISTANT_OTHER_UNSPE_ANTIBI.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: U22_AGENT_RESISTANT_OTHER_UNSPE_ANTIBI – Agent resistant to other and unspecified antibiotics

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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