Syndactyly

Q17_SYNDACTYLY

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — Q70 Cause of death: ICD-10 — Q70 2 out of 7 registries used, show all original rules.	89
4. Check minimum number of events None	89
5. Include endpoints None	89
6. Filter based on genotype QC (FinnGen only)	77

Control definitions (FinnGen only)

Control exclude: Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF4
Parent code in ICD-10: Q6[5-9]|Q7
Name in latin: Syndactylia

NAME	Q17_SYNDACTYLY
CONTROL_EXCLUDE	Q17_CONGEN_MALFO_DEFORMAT_MUSCULOS_SYSTEM
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	Q70
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	Q70
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Syndactyly based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	1551	578	972
Only index persons	1116	439	677
Unadjusted period prevalence (%)
Whole population	0.02	0.02	0.03
Only index persons	0.02	0.02	0.03
Median age at first event (years)
Whole population	2.12	3.83	1.06
Only index persons	4.99	9.40	2.12

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	77	49	28
Unadjusted period prevalence (%)	0.02	0.02	0.01
Median age at first event (years)	22.07	16.34	32.08

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
79: Matched controls
790

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

Q70.9

ICD-10 Finland

Syndactyly, unspecified

+∞

43.9

Q70.1

ICD-10 Finland

Webbed fingers

+∞

17.3

Q70.0

ICD-10 Finland

Fused fingers

+∞

15.1

NDT38

NOMESCO Finland

Correction of joined fingers

+∞

14.0

Q70.3

ICD-10 Finland

Webbed toes

+∞

11.7

AA1AD

NOMESCO Finland

CT of head and brain

4.6

9.0

7551A

ICD-9 Finland

Other congenital anomalies of limbs, Syndactyly[SYNDACTYLIA]

+∞

8.5

9493

FHL

Reconstruction or shaping of hand skin and soft tissues, e.g. syndactyl

+∞

7.4

ZXA00

NOMESCO Finland

Right side

4.1

6.6

ND2AA

NOMESCO Finland

Hand and fingers X-ray examination

4.6

6.5

G70.0

ICD-10 Finland

Myasthenia gravis

+∞

6.3

108

Kela drug reimbursment

Myasthenia gravis

+∞

6.3

75512

ICD-8 Finland

Other congenital anomalies of limbs, Syndactylia cum reductione phalangis, manus

+∞

6.3

N07AA02

ATC

pyridostigmine; systemic

+∞

6.3

A09

ICD-10 Finland

Other gastroenteritis and colitis of infectious and unspecified origin

3.4

6.1

114

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3007853) Bacteria identified in Skin by Aerobe culture

2.66

2.94

2.4

1.5

—

(3000924) Streptococcus pyogenes [Presence] in Throat by Organism specific culture

3.93

2.90

1.5

1.4

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

8.78

2.79

1.8

1.7

0.21

2.93

ug/l

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

8.78

2.79

2.2

2.0

—

(3032080) INR in Blood by Coagulation assay

221

2.16

2.77

18.3

8.0

1.25

1.12

inr

0.73

174

(3023368) Bacteria identified in Blood by Culture

133

2.29

2.71

4.0

3.8

—

(3012544) pH of Venous blood

2.53

2.35

7.8

4.7

7.39

7.37

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

268

2.00

2.34

9.6

8.1

1.21

1.22

mmol/l

0.32

246

(3044290) Cell count panel - Cerebral spinal fluid

4.90

2.31

1.7

2.0

—

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

107

2.16

2.10

6.0

2.6

62.50

323.02

ng/l

1.37

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

3.30

2.08

8.1

3.0

0.50

0.59

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.60

2.06

48.2

12.8

1.43

1.16

mmol/l

0.43

(3004789) Transferrin [Mass/volume] in Serum or Plasma

2.22

1.98

2.1

2.6

2.56

2.40

g/l

0.71

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

4.77

1.97

1.0

1.5

—

(3026285) Alpha 1 antitrypsin [Mass/volume] in Serum or Plasma

4.77

1.97

1.2

1.0

1.41

1.34

g/l

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.19

1.93

1.7

1.8

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

258

1.82

1.80

2.0

1.9

—

(3002582) Erythrocytes [#/volume] in Urine

205

1.84

1.79

4.5

3.0

14.05

60.84

e6/l

0.90

153

(42870588) Differential panel, method unspecified - Blood

224

1.81

1.74

7.8

6.3

—

(3030467) Casts [#/volume] in Urine by Automated count

173

1.85

1.71

2.7

3.1

0.17

0.25

e6/l

0.26

124

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.66

1.65

1.3

1.9

—

(4195642) Thrombophilia screening test

3.74

1.64

1.2

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.12

1.55

16.6

9.4

106.36

105.78

mmol/l

0.18

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

278

1.71

1.50

3.2

2.5

68.94

71.17

nmol/l

0.19

260

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.86

1.46

1.8

2.0

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

3.26

1.46

1.0

1.2

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

147

1.80

1.44

3.9

2.4

81.00

619.47

u/l

0.72

147

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

165

1.75

1.41

4.2

2.4

17.53

44.46

ng/l

0.50

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

1.38

0.0

2.2

—

4.79

—

(3009035) Cobalamin (Vitamin B12) [Moles/volume] in Serum or Plasma

1.94

1.34

1.7

1.5

746666998.13

433.79

pmol/l

0.78

(3015377) Calcium [Moles/volume] in Serum or Plasma

195

1.68

1.29

3.3

2.9

2.33

2.36

mmol/l

0.58

183

(3008230) Borrelia burgdorferi IgM Ab [Units/volume] in Serum

2.19

1.28

2.0

2.3

—

17.97

—

(3018095) Leukocytes [#/volume] in Urine

241

1.63

1.27

5.7

3.8

15.46

25.21

e6/l

0.61

154

(3022145) Colonoscopy Study observation

2.14

1.22

1.5

1.4

—

(3025941) Bacteria identified in Stool by Culture

2.14

1.22

1.8

1.2

—

(3024354) Oxygen [Partial pressure] in Venous blood

2.04

1.19

10.5

3.8

4.58

5.19

kpa

0.85

(3007628) Bicarbonate [Moles/volume] standard in Venous blood

2.10

1.17

9.6

5.1

24.35

23.81

mmol/l

—

(3004529) Oxygen [Partial pressure] adjusted to patient's actual temperature in Venous blood

2.60

1.17

5.6

3.3

66.84

53.85

—

(3013139) Helicobacter pylori Ag [Presence] in Stool

2.06

1.12

1.0

1.2

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.93

1.12

1.7

1.5

—

(3018418) pH of Serum or Plasma

149

1.66

1.11

4.4

3.8

7.40

7.39

0.40

104

(3015816) F5 gene p.Arg506Gln [Presence] in Blood or Tissue by Molecular genetics method

2.47

1.10

1.0

1.1

—

(3016888) Borrelia burgdorferi IgG Ab [Units/volume] in Serum

2.13

1.09

1.1

1.3

—

44.16

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.87

1.03

1.8

1.5

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

102

1.71

1.00

2.3

3.1

1.93

4.07

e6/l

—

(3022948) Iron [Moles/volume] in Serum or Plasma

1.67

0.89

2.3

2.5

16.46

15.10

umol/l

0.22

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

1.86

0.88

61.3

11.1

24.10

24.59

mmol/l

—

(40758558) Short blood count panel - Blood

203

1.50

0.87

5.2

6.2

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

1.82

0.85

1.9

2.3

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

107

1.62

0.84

2.1

3.1

1.78

0.96

e6/l

—

(3006504) Eosinophils/Leukocytes in Blood

337

1.45

0.84

7.8

5.8

2.90

2.78

0.18

318

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

1.95

0.83

85.5

17.4

23.67

24.46

mmol/l

—

(3006217) Methemoglobin/Hemoglobin.total in Arterial blood

1.95

0.83

85.5

17.7

0.48

0.59

—

(3013512) EKG study

142

1.55

0.83

2.9

2.6

—

(40768804) Tissue Pathology biopsy report

258

0.65

0.82

1.6

1.8

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

125

1.57

0.82

4.6

2.3

1.01

1.25

mg/l

0.15

(3000991) Gas panel - Venous blood

1.75

0.80

52.5

11.8

—

(1761868) Lipid panel - Serum or Plasma

267

0.66

0.79

2.6

2.5

—

(3003396) Base excess in Arterial blood by calculation

1.79

0.79

58.6

12.1

-0.37

0.87

mmol/l

—

(3016407) Fibrinogen [Mass/volume] in Platelet poor plasma by Coagulation assay

2.25

0.77

9.4

4.7

2.78

3.55

g/l

—

(40768443) Skin Pathology biopsy report

2.15

0.76

1.0

1.3

—

(3028626) Oxygen [Partial pressure] in Capillary blood

1.87

0.75

8.3

4.2

9.44

9.85

kpa

—

(3022096) Basophils/Leukocytes in Blood

335

1.39

0.70

7.9

5.9

0.73

0.67

0.39

317

(3018010) Neutrophils/Leukocytes in Blood

345

1.39

0.70

7.5

5.6

53.61

56.53

0.88

331

(3021960) Folate [Moles/volume] in Serum or Plasma

148

1.47

0.68

1.6

21.50

20.74

nmol/l

0.09

130

(21494755) Public health laboratory ask at order entry panel

105

0.54

0.67

1.3

1.2

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

1.77

0.65

1.0

1.8

—

(3026008) Bacteria identified in Urine by Culture

169

1.42

0.62

3.7

2.7

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

1.77

0.59

3.0

1.4

—

(3028653) Carboxyhemoglobin/Hemoglobin.total in Arterial blood

1.77

0.59

85.5

16.4

0.97

0.91

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

0.00

0.59

0.0

1.9

—

0.22

—

(3000620) Complement C3 [Mass/volume] in Serum or Plasma

0.00

0.59

0.0

1.9

—

1.18

—

(3044640) Blood type and Crossmatch panel - Blood

227

1.36

0.58

2.8

2.3

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.67

0.57

1.8

1.5

—

(3044889) 12 lead EKG panel

404

1.33

0.56

3.3

3.0

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

1.48

0.55

1.2

1.7

—

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

318

1.31

0.51

5.9

9.95

10.99

umol/l

0.34

301

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

328

1.31

0.51

3.9

2.9

—

estimate

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

606

1.41

0.49

4.5

4.1

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.50

0.48

1.9

3.5

4.76

4.84

pmol/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

223

0.75

0.43

2.8

2.5

—

(3009343) pH of Capillary blood

1.40

0.42

7.8

4.9

7.42

7.41

—

(3005719) IgG [Mass/volume] in Serum or Plasma

1.37

0.42

12.4

2.0

9.97

10.51

g/l

—

(3015916) Alpha-1-Fetoprotein [Units/volume] in Serum or Plasma

0.00

0.41

0.0

3.1

—

9.33

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.41

0.0

3.5

—

0.67

—

(3000494) Fungus identified in Specimen by Culture

1.47

0.41

3.2

1.3

—

(3009466) Valproate [Moles/volume] in Serum or Plasma

0.00

0.41

0.0

4.8

—

307.56

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

0.41

0.0

1.8

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

1.46

0.40

1.2

1.3

30.00

35.51

nmol/l

—

(3013721) Aspartate aminotransferase [Enzymatic activity/volume] in Serum or Plasma

248

1.27

0.40

4.6

2.9

35.14

30.65

u/l

0.28

239

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.41

0.39

1.6

1.4

—

(3015736) pH of Urine

290

1.24

0.35

4.7

3.0

6.19

6.31

0.27

160

(3022313) Gas panel - Capillary blood

1.39

0.35

8.0

5.5

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

0.67

0.35

1.0

1.4

—

(3002256) Pathology report gross observation

1.38

0.34

1.2

—

(3028026) IgM [Mass/volume] in Serum or Plasma

1.41

0.32

1.6

1.5

1.28

1.14

g/l

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

162

0.76

0.32

1.3

1.8

—

(3042936) Bacteria identified in Isolate by Culture

1.36

0.32

2.8

1.9

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

103

1.31

0.30

1.2

2.2

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

588

1.25

0.29

15.5

10.5

95.10

96.62

ml/min/173m2

0.23

520

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

123

0.79

0.22

2.0

—

(3043409) Potassium [Moles/volume] in Arterial blood

0.00

0.21

0.0

2.7

—

3.82

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

0.21

0.0

1.1

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

2.0

—

26.57

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

0.00

0.21

0.0

2.0

—

45.83

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.0

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.0

—

(40759850) Jo-1 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.0

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.0

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.0

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.0

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.0

—

(3018333) Ribosomal P Ab [Presence] in Serum

0.00

0.21

0.0

1.0

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.2

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

0.21

0.0

1.5

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.9

—

0.00

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.9

—

0.00

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

0.21

0.0

4.2

—

18.65

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

0.21

0.0

3.9

—

0.00

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.20

0.0

1.2

—

(3024666) Lithium [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

11.1

—

0.61

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

0.20

0.0

1.0

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.20

0.0

1.1

—

(3007164) IgA [Mass/volume] in Serum or Plasma

215

1.17

0.19

1.4

2.50

2.26

g/l

0.31

127

(40761536) Microorganisms panel - Urine sediment

1.17

0.19

3.2

3.1

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

584

0.86

0.19

3.6

3.3

1.28

1.19

mmol/l

0.31

550

(3012516) Albumin [Mass/volume] in Urine

141

0.82

0.18

2.8

3.4

8.39

105.28

mg/l

—

(3029937) Albumin [Presence] in Urine by Test strip

168

1.17

0.18

5.8

3.2

0.00

0.01

estimate

—

(3000492) Spirometry study

0.71

0.17

1.4

—

(3000764) Benzodiazepines [Presence] in Urine

0.77

0.16

1.7

1.4

—

(3028300) Cannabinoids [Presence] in Urine

0.75

0.16

1.7

1.4

—

(3027944) Amphetamines [Presence] in Urine

0.75

0.16

1.7

1.4

—

(3027008) Opiates [Presence] in Urine

0.75

0.16

1.7

1.4

—

(3021601) Nitrite [Presence] in Urine by Test strip

346

1.13

0.16

5.1

3.2

0.00

estimate

—

(3018171) Choriogonadotropin [Units/volume] in Serum or Plasma

1.23

0.16

3.1

2.5

837.30

8360.61

u/l

—

(3017732) Neutrophils [#/volume] in Blood

1.17

0.16

2.3

2.4

4.75

4.11

e9/l

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

681

1.24

0.14

22.4

11.7

25.86

21.53

mg/l

0.46

526

(46235355) HIV 1 and 2 tests - Meaningful Use set

280

0.89

0.13

2.0

2.3

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

231

1.12

0.12

2.4

1.8

101.46

96.37

pmol/l

0.20

124

(3035350) Ketones [Presence] in Urine by Test strip

350

1.11

0.12

5.2

3.3

0.00

estimate

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

233

1.11

0.10

1.4

1.6

0.66

2.13

u/ml

—

(3009261) Glucose [Presence] in Urine by Test strip

352

1.10

0.10

5.2

3.3

0.00

estimate

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

1.17

0.10

8.2

5.8

24.30

24.04

mmol/l

—

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

1.12

0.10

1.2

4.3

1.92

11.79

ug/l

—

(3023511) Choriogonadotropin [Units/volume] in Urine

1.09

0.10

1.2

1.3

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

165

1.12

0.10

3.1

2.4

—

(36660697) Celiac disease serology panel - Serum

1.16

0.09

1.1

1.2

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.10

0.09

1.2

1.3

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.78

0.08

1.8

1.4

—

(42868674) Cholesterol in HDL/Cholesterol.total [Molar ratio] in Serum or Plasma

0.77

0.08

3.4

3.6

34.40

33.16

—

(3041096) Erythrocytes [Presence] in Urine by Automated

204

0.91

0.08

5.9

2.6

0.13

0.00

estimate

—

(3016879) Cocaine [Presence] in Urine

0.82

0.08

1.7

1.4

—

(40768797) Stomach Pathology biopsy report

1.07

0.08

1.1

1.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

254

0.92

0.07

6.3

3.0

0.00

0.02

estimate

—

(3020682) Albumin/Creatinine [Ratio] in Urine

142

0.90

0.07

3.5

3.9

1.43

15.92

mg/mmol

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

202

0.92

0.06

2.8

2.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

141

0.91

0.06

2.2

2.3

—

(3026910) Gamma glutamyl transferase [Enzymatic activity/volume] in Serum or Plasma

502

0.94

0.05

5.3

3.5

41.14

37.35

u/l

0.14

484

(3003694) ABO and Rh group [Type] in Blood

282

1.04

0.02

1.7

—

(40760892) CBC W Ordered Manual Differential panel - Blood

163

1.05

0.01

4.6

3.9

—

(3026493) Urate [Moles/volume] in Serum or Plasma

128

1.02

0.00

2.1

3.2

270.77

317.90

umol/l

1.21

118

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

148

1.02

0.00

1.4

1.5

—

(3019832) Treponema pallidum Ab [Presence] in Serum

213

0.98

0.00

1.5

1.9

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

237

1.02

0.00

1.6

1.8

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

141

0.99

0.00

1.7

1.5

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

2.3

—

(37020937) Giardia lamblia DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

6.7

—

63.17

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

82.19

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.89

-0.00

1.0

1.8

—

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

0.43

—

(40760543) Extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.0

—

(37208534) Antinuclear antibody arbitrary concentration in serum

0.00

-0.00

0.0

1.0

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3000081) cloZAPine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

23.1

—

1872.86

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.0

—

(4211845) Urine protein measurement

0.00

-0.00

0.0

1.4

—

(40761511) CBC panel - Blood by Automated count

715

1.08

-0.00

16.2

9.5

—

(3043405) Microscopic observation [Identifier] in Specimen by Non-gynecological cytology method

0.00

-0.00

0.0

1.6

—

(3040370) OLANZapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.4

—

147.80

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3004616) Nuclear Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

-0.00

0.0

1.0

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

(3034988) Calcium [Moles/volume] in Capillary blood

0.00

-0.00

0.0

1.6

—

1.20

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.6

—

89.10

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

-0.00

0.0

1.6

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

-0.00

0.0

1.2

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.99

-0.00

1.5

1.6

—

(36305771) Cryptosporidium sp DNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.0

—

(3042111) Morphology [Interpretation] in Bone marrow Narrative

0.00

-0.00

0.0

2.2

—

(3041145) Herpes simplex virus IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3051611) Lipemic interference index of Serum or Plasma

0.00

-0.00

0.0

3.6

—

13.00

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.2

—

(21491868) Cryoglobulin [Mass/volume] in Serum

0.00

-0.00

0.0

1.0

—

(40768441) Liver Pathology biopsy report

0.00

-0.00

0.0

1.3

—

(3028679) Herpes simplex virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3038026) Centromere Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.92

-0.00

2.2

1.6

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

1.00

-0.00

1.4

1.5

82.50

49.46

ug/l

—

(3030136) 5-Hydroxyindoleacetate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

62.20

—

(42868544) Hantavirus puumala IgM Ab [Presence] in Serum or Plasma by Immunofluorescence

0.00

-0.00

0.0

1.0

—

(3003129) Base excess in Capillary blood by calculation

0.00

-0.00

0.0

1.3

—

-2.47

—

(3051651) Icteric interference index of Serum or Plasma

0.00

-0.00

0.0

3.4

—

0.80

—

(3041423) Sjogrens syndrome-A extractable nuclear 60kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(3039602) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Capillary blood

0.00

-0.00

0.0

1.4

—

1.21

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.0

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(3022411) Androstenedione [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.1

—

6.08

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

-0.00

0.0

1.0

—

(3008832) Norclozapine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

16.6

—

978.57

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

-0.00

0.0

1.3

—

(3013201) Beta-2-Microglobulin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

3.38

—

(3030408) 3-Methoxytyramine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.0

—

27.85

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.8

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

4.5

—

29.17

—

(4062490) Immunoglobulin typing, IgG

0.00

-0.00

0.0

1.2

—

(3020876) Protein [Mass/time] in 24 hour Urine

0.00

-0.00

0.0

1.7

—

0.69

—

(3023709) Somatotropin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

5.8

—

0.86

—

(3028334) Neisseria gonorrhoeae [Presence] in Specimen by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3006462) Nitrate [Presence] in Urine

0.00

-0.00

0.0

1.4

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

-0.00

0.0

1.4

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.6

—

Mortality – FinRegistry

↥

Association

Association between endpoint Q17_SYNDACTYLY and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have Q17_SYNDACTYLY.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: Q17_SYNDACTYLY – Syndactyly

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Syndactyly

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints