No definition available.
Excessive and redundant skin and subcutaneous tissue
L12_EXCESSSKINDANDSUBCUTIS
Endpoint definition
↥Report an error or suggest an improvement for this endpoint codes
Endpoint definition steps |
FinnGen |
|---|---|
Phenotype data |
557745 |
1. Apply sex-specific ruleNone |
557745 |
2. Check conditionsNone |
557745 |
3. Check pre-conditions, main-only, mode, registry filtersRegistry filters:
2 out of 7 registries used, show all original rules. |
83 |
4. Check minimum number of eventsNone |
83 |
5. Include endpointsNone |
83 |
6. Filter based on genotype QC (FinnGen only) |
78 |
Control definitions (FinnGen only)
- Control exclude
- L12_OTHERSKINSUBCUTIS
Extra metadata
- Level in the ICD hierarchy
- 4
- First used in FinnGen datafreeze
- DF2
Similar endpoints
↥List of similar endpoints to
Excessive and redundant skin and subcutaneous tissue
based on the number of shared cases.
Similar with more cases:
- Other disorders of skin and subcutaneous tissue, not elsewhere classified
- Other disorders of skin and subcutaneous tissue
- Diseases of the skin and subcutaneous tissue
- Any operation in hilmo
- Any prescribed medicine buy
Similar with less cases:
None
Case counts by codes
↥
Summary Statistics
↥-FinRegistry-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | |||
| Whole population | 49 | 48 | - |
| Only index persons | 49 | 48 | - |
| Unadjusted period prevalence (%) | |||
| Whole population | 0.00 | 0.00 | - |
| Only index persons | 0.00 | 0.00 | - |
| Median age at first event (years) | |||
| Whole population | - | 51.65 | - |
| Only index persons | 51.20 | 51.65 | - |
-FinnGen-
Key figures
| All | Female | Male | |
|---|---|---|---|
| Number of individuals | 78 | 70 | 8 |
| Unadjusted period prevalence (%) | 0.02 | 0.02 | 0.00 |
| Median age at first event (years) | 57.09 | 56.85 | 59.25 |
-FinRegistry-
Age distribution of first events
-FinnGen-
Age distribution of first events
-FinRegistry-
Year distribution of first events
-FinnGen-
Year distribution of first events
-FinRegistry-
Cumulative Incidence Function
No data
-FinnGen-
Cumulative Incidence Function
No data
CodeWAS
↥CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.
This is a new tool, please reach out using the contact form for feedback and improvement ideas.
First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.
Matched cohort
- Matched cases
- 82
- Matched controls
- 820
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
L98.7
ICD-10 Finland
Excessive and redundant skin and subcutaneous tissue
+∞
118.0
82
*
QBJ30
NOMESCO Finland
Correction of abdominal apron
69.4
19.0
21
*
E66.01
ICD-10 Finland
Obesity due to excess calories
6.1
12.7
29
68
UJD10
NOMESCO Finland
Esophagoscopy, gastroscopy and duodenoscopy
4.1
8.6
35
127
JDF11
NOMESCO Finland
Laparoscopic gastric bypass
25.1
8.3
11
5
N02AX02
ATC
tramadol; systemic, rectal
3.8
8.2
49
230
WX402
NOMESCO Finland
General anaesthesia
3.8
7.8
35
135
WZC30
NOMESCO Finland
Teaching
4.2
7.6
25
77
Z00.4
ICD-10 Finland
General psychiatric examination, not elsewhere classified
5.1
7.5
18
43
R42
ICD-10 Finland
Dizziness and giddiness
3.9
7.3
28
96
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
4.4
6.8
20
56
E66.8
ICD-10 Finland
Other obesity
6.4
6.6
17
32
LabWAS
↥OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
66
355
5.40
9.59
3.1
2.6
—
—
estimate
—
0
0
46
221
3.46
7.14
2.7
2.9
10.83
16.49
ng/l
1.45
26
125
43
227
2.88
5.25
4.1
3.1
—
—
—
0
0
27
113
3.07
4.98
1.8
3.2
0.72
0.83
e6/l
0.14
18
56
12
21
6.50
4.97
1.9
2.9
44.87
44.30
%
0.02
12
21
72
541
3.71
4.04
12.8
7.5
72.97
75.79
u/l
0.32
72
515
35
186
2.54
3.98
2.4
2.1
—
—
—
0
0
29
142
2.61
3.89
2.4
2.7
223.53
412.35
ng/l
0.95
22
116
34
185
2.43
3.62
3.2
3.3
0.18
0.23
e6/l
0.17
29
134
18
71
2.97
3.59
2.2
6.6
105.17
104.44
mmol/l
0.39
18
71
9
19
5.18
3.34
1.7
1.9
25.94
25.53
mmol/l
—
9
19
11
29
4.21
3.33
1.2
1.2
—
—
—
0
0
10
26
4.23
3.10
3.9
3.3
12.70
43.75
u/ml
—
10
26
55
395
2.19
2.78
5.5
3.5
0.00
0.00
estimate
-0.00
14
80
54
388
2.15
2.69
5.6
3.5
0.00
0.00
estimate
-0.00
14
77
43
284
2.08
2.68
5.8
3.1
0.00
0.01
estimate
0.49
12
69
17
76
2.56
2.66
1.9
2.5
2.53
2.45
g/l
0.25
17
67
54
390
2.13
2.63
5.7
3.5
0.00
0.00
estimate
-0.00
14
79
21
105
2.34
2.60
1.8
3.3
3.84
3.63
e6/l
0.03
13
48
33
202
2.06
2.48
5.3
3.3
0.00
0.00
estimate
-0.00
11
76
16
72
2.52
2.47
1.9
2.6
29.80
24.06
%
1.17
16
67
8
22
3.91
2.43
1.5
1.2
—
—
—
0
0
11
41
2.94
2.31
1.6
1.3
—
—
—
0
0
6
13
4.89
2.31
3.0
5.3
15.33
26.92
u/ml
—
6
13
7
18
4.15
2.31
1.0
1.3
—
—
—
0
0
42
289
1.93
2.21
2.6
2.0
99.69
102.72
pmol/l
0.19
32
153
9
33
2.93
2.00
1.6
9.6
1.06
1.18
%
—
9
33
9
33
2.93
2.00
1.6
9.5
0.77
0.70
%
—
9
33
82
766
+∞
1.94
25.7
14.5
66.93
68.29
umol/l
0.38
82
754
26
162
1.89
1.78
6.1
3.3
1.02
1.02
kg/l
0.20
18
103
8
30
2.84
1.77
1.6
1.3
—
4.53
—
0
7
12
56
2.34
1.71
3.2
3.5
82.60
71.50
ml/min/173m2
—
5
22
11
50
2.39
1.65
1.1
1.0
—
—
—
0
0
5
14
3.73
1.64
1.0
1.1
—
—
—
0
0
77
702
2.59
1.38
5.6
4.1
5.67
5.63
mmol/l
0.17
72
662
13
73
1.93
1.19
7.2
5.2
—
—
—
0
0
31
228
1.58
1.12
1.4
1.3
0.67
1.33
u/ml
—
7
69
26
184
1.60
1.10
3.4
3.4
8.83
9.63
mg/mmol
0.04
18
100
23
160
1.61
1.04
2.1
2.2
—
—
—
0
0
7
35
2.09
1.03
1.6
1.9
—
—
—
0
0
27
198
1.54
0.98
1.4
1.6
—
—
—
0
0
21
145
1.60
0.97
2.1
2.1
—
—
—
0
0
6
27
2.32
0.95
2.0
2.7
1.05
1.03
%
—
6
27
10
63
1.67
0.65
2.2
3.1
—
—
—
0
0
5
29
1.77
0.65
1.4
1.6
68.90
55.95
ug/l
—
5
29
5
29
1.77
0.65
3.2
1.7
0.23
0.23
g/l
—
5
29
12
80
1.59
0.64
2.9
1.9
—
—
—
0
0
6
36
1.72
0.58
1.3
2.5
24.83
24.75
mmol/l
—
6
36
26
208
1.37
0.58
1.7
1.9
—
—
—
0
0
6
38
1.62
0.55
1.5
1.6
—
—
—
0
0
14
101
1.47
0.54
2.9
2.0
—
—
—
0
0
27
220
1.34
0.53
4.4
2.7
0.00
0.02
estimate
0.49
12
66
7
50
1.44
0.46
2.4
2.0
2.47
2.77
mg/l
—
7
33
0
15
0.00
0.41
0.0
1.9
—
7.16
—
0
15
0
15
0.00
0.41
0.0
1.2
—
0.74
—
0
5
82
805
+∞
0.41
32.6
19.1
90.60
90.57
fl
0.02
82
799
82
805
+∞
0.41
32.7
19.5
40.45
40.26
%
0.22
82
799
5
34
1.50
0.41
1.4
6.5
25.10
24.92
mmol/l
—
5
34
62
578
1.30
0.40
3.7
3.8
—
—
—
0
0
5
35
1.46
0.40
2.2
1.6
—
—
—
0
0
5
36
1.41
0.39
2.2
1.9
—
—
—
0
0
14
111
1.32
0.32
2.4
3.1
5.50
34.10
ng/l
—
8
71
22
187
1.24
0.31
1.4
1.4
54.92
18.53
iu/ml
—
5
65
6
80
0.73
0.25
1.0
1.4
9.95
24.35
iu/l
—
6
73
5
39
1.30
0.23
1.0
1.1
1.59
1.61
g/l
—
5
39
5
40
1.27
0.23
1.0
1.1
0.70
0.83
g/l
—
5
40
0
12
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.7
—
12.95
—
0
13
15
173
0.84
0.19
1.5
1.4
1.26
8.99
u/ml
—
8
77
8
69
1.18
0.17
1.6
1.5
—
—
—
0
0
11
96
1.17
0.11
2.5
1.7
—
—
—
0
0
7
66
1.07
0.08
1.7
1.6
—
—
—
0
0
7
83
0.83
0.07
7.1
4.1
34.14
32.14
%
—
7
58
11
109
1.01
0.00
1.6
1.6
1.28
1.29
%
0.02
11
100
0
8
0.00
0.00
0.0
2.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
5
53
0.94
-0.00
1.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
6.86
—
0
6
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.8
—
294.33
—
0
6
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
Mortality – FinRegistry
↥Association
Association between endpoint L12_EXCESSSKINDANDSUBCUTIS and mortality.
Females
No dataMales
No dataMortality risk
Mortality risk for people of age
years, who have L12_EXCESSSKINDANDSUBCUTIS.| N-year risk | Females | Males |
|---|---|---|
| 1 | No data | No data |
| 5 | No data | No data |
| 10 | No data | No data |
| 15 | No data | No data |
| 20 | No data | No data |
Relationships between endpoints
↥Index endpoint: L12_EXCESSSKINDANDSUBCUTIS – Excessive and redundant skin and subcutaneous tissue
GWS hits: -
Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
Loading data