Acquired coagulation factor deficiency

D3_ACQCOAFACDEF

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — D68.4 Hospital discharge: ICD-9 — 2867 Cause of death: ICD-10 — D68.4 Cause of death: ICD-9 — 2867 2 out of 7 registries used, show all original rules.	66
4. Check minimum number of events None	66
5. Include endpoints None	66
6. Filter based on genotype QC (FinnGen only)	61

Control definitions (FinnGen only)

Control exclude: D3_COAGDEF_PURPUR_HAEMORRHAGIC

Extra metadata

Level in the ICD hierarchy: 4
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: D68
Name in latin: Deficientia factoris coagulationis acquisita

NAME	D3_ACQCOAFACDEF
CONTROL_EXCLUDE	D3_COAGDEF_PURPUR_HAEMORRHAGIC
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	D684
HD_ICD_9	2867
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	D684
COD_ICD_9	2867
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Acquired coagulation factor deficiency based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	397	225	170
Only index persons	317	190	127
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.00
Only index persons	0.01	0.01	0.00
Median age at first event (years)
Whole population	59.15	53.57	66.31
Only index persons	55.43	47.69	67.01

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	61	41	20
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	61.16	55.92	71.91

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
62: Matched controls
620

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

D68.4

ICD-10 Finland

Acquired coagulation factor deficiency

+∞

71.2

D68.8

ICD-10 Finland

Other specified coagulation defects

+∞

11.8

D68.2

ICD-10 Finland

Hereditary deficiency of other clotting factors

+∞

10.7

B02AA02

ATC

tranexamic acid; systemic

6.1

10.3

R58

ICD-10 Finland

Haemorrhage, not elsewhere classified

29.3

7.8

D68.9

ICD-10 Finland

Coagulation defect, unspecified

+∞

7.4

2867X

ICD-9 Finland

Coagulation defects, Acquired coagulation factor deficiency[DEFECTIO COAGULATIONIS, E DEFICIENTIA NON DEFINITA]

+∞

7.4

WW500

NOMESCO Finland

Blood transfusion

16.3

7.2

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3006109) Coagulation factor IX activity actual/normal in Platelet poor plasma by Coagulation assay

+∞

12.95

2.4

0.0

109.58

—

(3000515) Antithrombin actual/normal in Platelet poor plasma by Chromogenic method

18.93

11.30

11.9

1.0

92.94

101.83

0.54

(3004588) Protein electrophoresis panel - Serum or Plasma

6.23

9.39

5.0

1.3

—

(42870588) Differential panel, method unspecified - Blood

176

4.28

7.26

7.5

4.0

—

(3023520) Reticulocytes [#/volume] in Blood

4.89

7.17

2.6

1.9

89.26

69.08

e9/l

0.76

(3032080) INR in Blood by Coagulation assay

271

4.85

6.65

28.3

16.3

1.47

1.29

inr

1.01

225

(40761593) Coagulation factor VIII Ab [Presence] in Platelet poor plasma by Immunoassay

+∞

6.35

1.3

0.0

—

(43055222) Platelet function.collagen + Adenosine diphosphate induced and EPINEPHrine induced panel - Blood

+∞

5.27

3.0

0.0

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

3.96

5.13

5.5

4.5

—

(3037756) Immunofixation for Serum or Plasma

10.28

4.97

3.1

1.2

—

(3037522) Nuclear Ab [Titer] in Serum

3.46

4.53

1.2

1.4

784.00

474.00

titre

—

(3031040) Bacteria [#/volume] in Urine by Automated count

379

3.74

4.07

5.9

5.1

—

334.08

—

(3024403) Complement+Immunoglobulin [Units/volume] in Red Blood Cells

6.81

3.98

1.2

1.3

—

(40761536) Microorganisms panel - Urine sediment

3.56

3.89

6.1

5.0

—

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

278

3.01

3.83

13.3

6.3

1.21

mmol/l

0.03

235

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

126

2.83

3.73

7.2

2.1

—

(40767503) Oxygen content in Capillary blood by calculation

6.88

3.63

2.3

3.2

15.86

16.34

—

(3021589) Normoblasts [#/volume] in Blood

245

2.78

3.62

22.2

12.1

0.00

e9/l

0.37

195

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

5.35

3.38

1.1

1.4

—

(3017181) Myelocytes/Leukocytes in Blood

3.33

3.35

8.6

5.0

1.14

0.72

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

9.32

3.34

1.2

1.1

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

9.32

3.34

1.2

1.1

—

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

5.23

3.03

4.1

1.5

—

(3022806) Fractional oxyhemoglobin in Capillary blood

7.23

2.94

2.3

2.8

86.68

90.78

—

(3010421) pH of Blood

4.93

2.90

8.1

5.7

7.42

7.41

—

(3028271) Lactate [Moles/volume] in Capillary blood

5.48

2.81

2.1

2.4

1.90

1.50

mmol/l

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

8.92

2.80

1.2

—

(3021960) Folate [Moles/volume] in Serum or Plasma

185

2.35

2.73

1.6

1.7

17.27

22.49

nmol/l

1.31

151

(3025468) Yersinia sp identified in Specimen by Organism specific culture

7.64

2.59

1.2

1.1

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

7.64

2.59

1.2

1.1

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

7.64

2.59

1.2

1.1

—

(3044640) Blood type and Crossmatch panel - Blood

180

2.29

2.57

8.4

2.1

—

(3030467) Casts [#/volume] in Urine by Automated count

174

2.25

2.46

3.1

3.3

0.14

0.31

e6/l

0.97

128

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

5.40

2.46

1.5

1.2

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

4.01

2.46

2.0

1.1

—

(3049717) Cytology report of Urine Cyto stain

4.01

2.46

3.1

3.0

—

(3041096) Erythrocytes [Presence] in Urine by Automated

167

2.23

2.40

5.1

4.1

0.00

estimate

-0.00

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

257

2.24

2.39

6.7

2.6

—

estimate

—

(3020059) Calcium [Moles/volume] corrected for albumin in Serum or Plasma

129

2.24

2.26

6.4

2.9

2.43

2.47

mmol/l

0.83

115

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

206

2.14

2.23

3.1

3.3

—

(3035933) Granulocytes/Leukocytes in Blood

4.62

2.21

2.3

2.9

59.50

65.89

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.32

2.12

2.1

1.8

—

(3035715) Granulocytes [#/volume] in Blood

5.33

2.11

1.6

1.9

4.19

6.01

e9/l

—

(3036086) Jo-1 extractable nuclear Ab [Units/volume] in Serum by Immunoassay

4.31

2.09

1.0

1.2

—

(3042936) Bacteria identified in Isolate by Culture

2.35

2.02

3.9

2.2

—

(36304419) Bacteria [Presence] in Urine

168

2.08

2.01

3.0

3.1

—

estimate

—

(3027315) Oxygen [Partial pressure] in Blood

4.03

1.98

10.0

4.2

8.15

8.40

kpa

—

(3013290) Carbon dioxide [Partial pressure] in Blood

4.03

1.98

10.0

4.3

5.08

4.97

kpa

—

(1616796) Gas panel - Central venous blood

4.84

1.98

7.8

4.6

—

(40768804) Tissue Pathology biopsy report

223

2.03

1.95

2.7

2.1

—

(3021440) Promyelocytes/Leukocytes in Blood

2.63

1.90

10.4

5.2

0.20

0.07

—

(3002179) Metamyelocytes/Leukocytes in Blood

2.63

1.90

9.6

4.8

0.60

1.13

—

(3016293) Bicarbonate [Moles/volume] in Serum or Plasma

2.83

1.89

11.8

5.5

25.57

25.21

mmol/l

—

(3017766) Complement C4 [Mass/volume] in Serum or Plasma

3.79

1.88

3.2

1.3

0.14

0.22

g/l

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

217

1.98

1.85

5.9

4.6

34.92

35.18

ng/l

0.01

162

(3023368) Bacteria identified in Blood by Culture

148

2.01

1.80

7.4

4.4

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

4.08

1.75

1.0

1.4

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

338

2.04

1.73

6.6

4.2

6.61

6.63

mmol/l

0.02

318

(3022313) Gas panel - Capillary blood

3.02

1.70

6.3

1.9

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

3.21

1.62

3.0

1.2

0.00

g/l

—

(3003338) MCHC [Entitic Mass/volume] in Red Blood Cells

413

0.53

1.58

60.3

22.2

327.69

330.52

g/l

0.96

413

(3002582) Erythrocytes [#/volume] in Urine

208

1.86

1.55

3.2

3.4

10.42

333.31

e6/l

0.53

160

(3013512) EKG study

199

1.86

1.55

4.9

3.9

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

3.05

1.54

1.3

1.0

—

(4035726) Immunohistochemistry procedure

2.26

1.43

1.7

1.3

—

(40760892) CBC W Ordered Manual Differential panel - Blood

125

1.89

1.40

10.0

5.4

—

(3007853) Bacteria identified in Skin by Aerobe culture

2.16

1.39

2.6

1.6

—

(3007220) Creatine kinase [Enzymatic activity/volume] in Serum or Plasma

180

1.77

1.31

3.2

1.9

152.54

171.04

u/l

0.18

171

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

265

1.74

1.28

2.1

2.2

95.63

95.98

pmol/l

0.02

125

(3018095) Leukocytes [#/volume] in Urine

227

1.73

1.28

3.9

4.3

211.28

72.80

e6/l

0.40

160

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

218

1.73

1.27

5.3

4.5

0.00

0.02

estimate

—

(3003694) ABO and Rh group [Type] in Blood

129

1.81

1.26

1.5

—

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

105

1.85

1.22

1.2

1.3

325.48

7.43

u/ml

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

2.20

1.20

2.0

1.3

—

(40768797) Stomach Pathology biopsy report

1.96

1.18

1.2

1.3

—

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

2.63

1.17

2.0

2.1

—

(3015235) Bicarbonate [Moles/volume] in Capillary blood

2.63

1.17

1.4

2.3

24.34

24.98

mmol/l

—

(40768443) Skin Pathology biopsy report

2.50

1.16

1.3

—

(3029937) Albumin [Presence] in Urine by Test strip

170

1.67

1.08

5.8

4.8

0.00

estimate

-0.00

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

1.92

1.05

2.0

1.6

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.98

1.04

1.2

1.7

—

(3000492) Spirometry study

2.12

1.04

1.0

1.5

—

(40758558) Short blood count panel - Blood

182

1.63

1.00

16.5

5.5

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

2.10

0.89

2.5

1.5

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.90

0.81

1.3

3.6

4.00

4.55

pmol/l

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

0.00

0.79

0.0

1.2

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.08

0.74

3.6

1.9

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

129

0.56

0.74

1.8

1.3

—

1.60

—

(3048689) Calprotectin [Mass/mass] in Stool

1.76

0.73

1.6

1.9

156.00

157.78

ug/g

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.56

0.61

1.6

1.9

—

(3008898) HLA-B27 [Presence]

0.00

0.61

0.0

1.2

—

(3027273) Bicarbonate [Moles/volume] in Venous blood

0.00

0.59

0.0

3.4

—

23.73

—

(40761511) CBC panel - Blood by Automated count

523

1.73

0.58

42.7

15.3

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

1.61

0.56

2.2

1.7

—

(3022145) Colonoscopy Study observation

1.56

0.50

1.1

1.4

—

(3016417) Amylase.pancreatic [Enzymatic activity/volume] in Serum or Plasma

1.55

0.49

1.7

2.7

86.00

34.92

u/l

—

(3014111) Lactate [Moles/volume] in Serum or Plasma

1.55

0.49

9.1

5.5

1.28

1.34

mmol/l

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.48

0.44

2.2

1.6

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.46

0.44

2.1

1.5

—

(3019060) Gas panel - Arterial blood

1.67

0.44

2.2

4.8

—

(3009261) Glucose [Presence] in Urine by Test strip

308

1.31

0.42

5.3

4.4

0.00

estimate

-0.00

(3016879) Cocaine [Presence] in Urine

0.00

0.42

0.0

1.2

—

(3000764) Benzodiazepines [Presence] in Urine

0.00

0.42

0.0

1.2

—

(3027008) Opiates [Presence] in Urine

0.00

0.41

0.0

1.2

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.41

0.0

1.5

—

(3027944) Amphetamines [Presence] in Urine

0.00

0.41

0.0

1.2

—

(3028300) Cannabinoids [Presence] in Urine

0.00

0.41

0.0

1.2

—

(3017732) Neutrophils [#/volume] in Blood

1.45

0.41

5.3

3.0

3.99

4.34

e9/l

—

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

0.00

0.41

0.0

1.1

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

0.00

0.41

0.0

1.1

—

(42529406) Shigella sp [Presence] in Stool by Culture

0.00

0.41

0.0

1.1

—

(3002256) Pathology report gross observation

1.42

0.41

1.1

1.2

—

(4034850) Laboratory test

0.00

0.40

0.0

12.9

—

(21494755) Public health laboratory ask at order entry panel

1.42

0.39

1.0

1.5

—

(3000494) Fungus identified in Specimen by Culture

1.33

0.39

2.2

1.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

301

1.29

0.38

5.4

4.3

0.00

estimate

-0.00

(40761535) Cells panel - Urine sediment

1.47

0.37

2.5

3.1

—

(3035350) Ketones [Presence] in Urine by Test strip

307

1.24

0.30

5.4

4.3

0.00

estimate

-0.00

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

309

1.22

0.27

3.2

3.3

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

173

1.23

0.25

2.8

2.6

56.00

56.58

u/l

0.03

159

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.31

0.23

2.0

1.3

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

506

1.33

0.22

6.1

5.5

5.98

5.99

mmol/l

0.02

460

(3026389) Candida sp identified in Specimen by Organism specific culture

0.00

0.21

0.0

1.3

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.1

—

(3023419) Bacteria identified in Sputum by Culture

0.00

0.21

0.0

2.0

—

(3023511) Choriogonadotropin [Units/volume] in Urine

0.00

0.21

0.0

1.4

—

(40768800) Prostate Pathology biopsy report

0.00

0.21

0.0

1.3

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

0.21

0.0

1.6

—

(3032836) C peptide [Moles/volume] in Serum or Plasma --fasting

0.00

0.21

0.0

1.0

—

1.03

—

(36032269) Testosterone Free [Moles/volume] in Serum or Plasma by calculation

0.00

0.21

0.0

1.6

—

206.30

—

(3045716) Anion gap in Serum or Plasma by calculation

0.00

0.21

0.0

1.8

—

10.30

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.21

0.0

1.2

—

(3008037) Lactate [Moles/volume] in Venous blood

0.00

0.21

0.0

4.4

—

2.06

—

(3026008) Bacteria identified in Urine by Culture

205

1.19

0.21

4.5

2.9

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.28

0.21

1.8

1.9

—

(3047181) Lactate [Moles/volume] in Blood

0.00

0.21

0.0

6.1

—

1.32

—

(3004248) Sex hormone binding globulin [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.6

—

46.08

—

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

1.24

0.17

2.6

2.7

0.60

0.91

e6/l

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

0.80

0.15

1.5

1.4

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.18

0.10

1.8

1.6

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

1.09

0.10

2.0

1.4

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.08

0.09

2.2

2.1

—

(3015736) pH of Urine

241

0.93

0.05

3.6

3.8

5.91

6.12

0.34

126

(3020682) Albumin/Creatinine [Ratio] in Urine

190

0.93

0.04

5.7

3.8

3.23

8.84

mg/mmol

—

112

(1761868) Lipid panel - Serum or Plasma

188

0.94

0.02

5.1

3.1

—

(3009508) Creatinine [Moles/volume] in Urine

193

1.05

0.01

3.6

3.1

6.96

7.27

mmol/l

0.14

154

(3025839) Triglyceride [Moles/volume] in Serum or Plasma

225

0.97

0.00

2.6

1.9

1.10

1.37

mmol/l

1.09

184

(3012516) Albumin [Mass/volume] in Urine

182

0.98

0.00

3.9

3.3

30.10

60.50

mg/l

—

115

(3038515) Glucose [Moles/volume] in Venous blood

0.00

-0.00

0.0

5.2

—

7.87

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

-0.00

0.0

1.0

—

(43055361) Metamyelocytes/Leukocytes [Pure number fraction] in Blood by Manual count

0.00

-0.00

0.0

4.4

—

0.20

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

1.03

-0.00

14.8

5.8

105.38

103.95

mmol/l

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.0

—

(44790049) Parainfluenza type 3 nucleic acid detection

0.00

-0.00

0.0

1.0

—

(44806118) Parainfluenza type 4 nucleic acid detection

0.00

-0.00

0.0

1.0

—

(1175715) Chlamydophila pneumoniae IgM Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.3

—

(3034603) RHD gene allele [Genotype] in Blood or Tissue by Molecular genetics method Nominal

0.00

-0.00

0.0

1.0

—

(40764127) Haemophilus influenzae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

(3002523) Influenza virus A Ag [Presence] in Specimen

0.00

-0.00

0.0

1.0

—

(3032699) Streptococcus pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.9

—

(3039000) Anion gap in Blood by calculation

0.00

-0.00

0.0

5.9

—

10.25

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

-0.00

0.0

1.6

—

(3018559) Microscopic observation [Identifier] in Buccal smear by Cyto stain

0.00

-0.00

0.0

1.5

—

(3042975) Streptococcus sp identified in Isolate by Organism specific culture

0.00

-0.00

0.0

1.0

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

0.94

-0.00

1.4

2.0

—

(3035285) Chloride [Moles/volume] in Venous blood

0.00

-0.00

0.0

5.3

—

106.33

—

(3041354) Potassium [Moles/volume] in Venous blood

0.00

-0.00

0.0

5.3

—

4.05

—

(3045788) Cell count panel - Pleural fluid

0.00

-0.00

0.0

1.0

—

(3049506) Microalbumin [Mass/time] in Urine collected for unspecified duration

0.00

-0.00

0.0

1.8

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

0.00

-0.00

0.0

5.3

—

1.19

—

(44790048) Parainfluenza type 2 nucleic acid detection

0.00

-0.00

0.0

1.0

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

60.30

—

(3003740) Influenza virus B Ag [Presence] in Specimen

0.00

-0.00

0.0

1.0

—

(3003265) Liver kidney microsomal Ab [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.3

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

2.0

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

-0.00

0.0

1.2

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

-0.00

0.0

2.4

—

(4146454) Self-monitoring of blood glucose

0.00

-0.00

0.0

3.6

—

(3013727) Leukocytes other/Leukocytes in Blood

0.00

-0.00

0.0

4.4

—

51.00

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.3

—

(36304997) Mycobacterium tuberculosis stimulated gamma interferon release by CD4+ and CD8+ T-cells [Units/volume] in Blood

0.00

-0.00

0.0

1.6

—

(3018572) Chloride [Moles/volume] in Blood

0.00

-0.00

0.0

5.9

—

104.13

—

(3021447) Carbon dioxide [Partial pressure] in Venous blood

1.02

-0.00

14.2

4.9

5.80

5.79

kpa

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.2

—

(3011363) Streptococcus pneumoniae Ag [Presence] in Urine

0.00

-0.00

0.0

1.0

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(44790047) Parainfluenza type 1 nucleic acid detection

0.00

-0.00

0.0

1.0

—

(3037875) Bordetella parapertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.7

—

Mortality – FinRegistry

↥

Association

Association between endpoint D3_ACQCOAFACDEF and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have D3_ACQCOAFACDEF.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: D3_ACQCOAFACDEF – Acquired coagulation factor deficiency

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Acquired coagulation factor deficiency

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints