Thoracic root disorders

G6_THROOT

peripheral nervous system disease: A disease involving the peripheral nervous system.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions None	557745
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — G54.3 Hospital discharge: ICD-9 — 3533 Cause of death: ICD-10 — G54.3 Cause of death: ICD-9 — 3533 2 out of 7 registries used, show all original rules.	77
4. Check minimum number of events None	77
5. Include endpoints None	77
6. Filter based on genotype QC (FinnGen only)	63

Control definitions (FinnGen only)

Control exclude: G6_NERPLEX

Extra metadata

Level in the ICD hierarchy: 3
First used in FinnGen datafreeze: DF2
Parent code in ICD-10: G54
Name in latin: Morbositates radicum nervorum thoracicorum non alibi classificatae

NAME	G6_THROOT
CONTROL_EXCLUDE	G6_NERPLEX
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	G543
HD_ICD_9	3533
HD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	G543
COD_ICD_9	3533
COD_ICD_8	$!$	The FinnGen clinical team has checked and no code can be used for this rule.
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Thoracic root disorders based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	501	279	218
Only index persons	448	254	194
Unadjusted period prevalence (%)
Whole population	0.01	0.01	0.01
Only index persons	0.01	0.01	0.01
Median age at first event (years)
Whole population	52.51	54.30	50.10
Only index persons	51.22	52.91	49.02

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	63	36	27
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	49.44	46.29	53.64

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

Matched cohort

Matched cases
66: Matched controls
660

Code

Vocabulary

Description

Odds Ratio

-log₁₀(p)

N matched cases

N matched controls

G54.3

ICD-10 Finland

Thoracic root disorders, not elsewhere classified

+∞

80.7

N03AX12

ATC

[U] gabapentin; oral

7.9

14.3

N03AX16

ATC

[U] pregabalin

7.0

14.0

N06AX21

ATC

duloxetine; oral

8.3

13.0

M79.2

ICD-10 Finland

Neuralgia and neuritis, unspecified

53.0

11.4

G54.0

ICD-10 Finland

Brachial plexus disorders

102.6

8.6

N02AX02

ATC

tramadol; systemic, rectal

4.4

7.9

197

WX700

NOMESCO Finland

Respiratory and circulatory monitoring

5.2

7.5

G50.1

ICD-10 Finland

Atypical facial pain

+∞

7.4

M54.5

ICD-10 Finland

Low back pain

4.0

7.2

160

M54.9

ICD-10 Finland

Dorsalgia, unspecified

4.9

7.1

M51.3

ICD-10 Finland

Other specified intervertebral disc degeneration

9.5

7.1

N06AA09

ATC

amitriptyline; systemic

6.8

6.7

M01AE03

ATC

ketoprofen; systemic, rectal

3.8

6.7

158

M51.1

ICD-10 Finland

Lumbar and other intervertebral disc disorders with radiculopathy

4.8

6.6

3533A

ICD-9 Finland

Nerve root and plexus disorders, Thoracic root lesions, not elsewhere classified

+∞

6.3

ACC59

NOMESCO Finland

Decompression and freeing of adhesions of peripheral nerve: other or unspecified

+∞

6.3

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3018418) pH of Serum or Plasma

161

3.50

5.91

3.5

3.8

7.40

0.16

124

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

216

3.16

4.93

2.7

2.2

93.24

98.08

pmol/l

0.33

115

(3024561) Albumin [Mass/volume] in Serum or Plasma

230

2.88

4.19

10.3

5.3

34.31

35.44

g/l

0.57

221

(3019150) Specific gravity of Urine by Refractometry

121

2.90

4.02

4.4

4.5

1.02

kg/l

0.06

(3035995) Alkaline phosphatase [Enzymatic activity/volume] in Serum or Plasma

420

3.61

3.94

11.4

7.7

77.25

76.87

u/l

0.03

395

(3007164) IgA [Mass/volume] in Serum or Plasma

103

2.89

3.78

1.4

1.6

2.55

3.20

g/l

0.48

(42870588) Differential panel, method unspecified - Blood

171

2.69

3.76

6.1

5.5

—

(3018010) Neutrophils/Leukocytes in Blood

259

2.71

3.67

6.7

5.8

60.14

58.19

0.49

253

(3035350) Ketones [Presence] in Urine by Test strip

288

2.77

3.64

4.3

4.0

0.00

23.54

estimate

—

(3009261) Glucose [Presence] in Urine by Test strip

288

2.77

3.64

4.3

4.0

0.00

estimate

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

242

2.66

3.62

3.8

3.2

—

estimate

—

(3021601) Nitrite [Presence] in Urine by Test strip

282

2.68

3.49

4.3

3.9

0.00

estimate

—

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

2.81

3.42

3.6

2.0

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

2.97

3.41

3.7

1.8

—

(3004789) Transferrin [Mass/volume] in Serum or Plasma

2.84

3.16

1.8

2.4

2.39

2.33

g/l

0.13

(3022948) Iron [Moles/volume] in Serum or Plasma

2.77

3.14

1.9

2.4

11.09

14.60

umol/l

1.05

(3015736) pH of Urine

227

2.43

3.10

3.7

6.31

6.21

0.25

134

(3006140) Bilirubin.total [Moles/volume] in Serum or Plasma

293

2.51

3.06

9.4

6.8

10.27

10.82

umol/l

0.19

277

(3031040) Bacteria [#/volume] in Urine by Automated count

347

2.60

2.92

5.3

5.0

—

1268.00

—

(3019060) Gas panel - Arterial blood

3.74

2.74

14.0

5.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

2.70

2.67

4.0

1.8

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

398

2.68

2.66

5.7

4.0

14.92

11.99

mm/h

0.48

373

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

5.87

2.60

2.2

2.4

311.03

233.27

ug/l

—

(3026493) Urate [Moles/volume] in Serum or Plasma

148

2.25

2.47

2.5

2.7

317.85

341.32

umol/l

0.56

132

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

2.38

2.27

1.3

1.2

9.46

5.02

u/ml

—

(3028026) IgM [Mass/volume] in Serum or Plasma

3.09

2.25

1.6

1.8

1.52

1.15

g/l

—

(40771025) 25-Hydroxyvitamin D3+25-Hydroxyvitamin D2 [Moles/volume] in Serum or Plasma

231

2.10

2.24

3.0

2.5

81.87

76.53

nmol/l

0.51

209

(40758558) Short blood count panel - Blood

162

2.13

2.21

8.7

6.6

—

(3005719) IgG [Mass/volume] in Serum or Plasma

2.86

2.21

3.0

4.0

8.61

11.28

g/l

2.19

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

2.48

2.18

1.8

2.5

18.33

23.47

0.71

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

181

2.07

2.13

2.9

3.1

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

3.79

2.12

2.3

2.0

—

(3003458) Phosphate [Moles/volume] in Serum or Plasma

2.40

2.06

5.5

6.5

1.21

1.00

mmol/l

0.91

(3013139) Helicobacter pylori Ag [Presence] in Stool

3.60

2.03

1.1

1.4

—

(3012544) pH of Venous blood

2.60

2.01

3.4

3.1

7.35

7.39

—

(3044640) Blood type and Crossmatch panel - Blood

167

2.04

2.01

2.7

2.8

—

(3030467) Casts [#/volume] in Urine by Automated count

134

2.10

2.01

3.0

2.8

1.64

0.24

e6/l

0.46

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

229

2.00

4.2

3.9

0.00

0.05

estimate

—

(3023368) Bacteria identified in Blood by Culture

144

2.05

1.93

5.0

4.7

—

(40761535) Cells panel - Urine sediment

2.81

1.88

4.9

3.7

—

(3002582) Erythrocytes [#/volume] in Urine

162

2.00

1.88

3.2

3.1

21.99

36.04

e6/l

0.38

126

(3012095) Magnesium [Moles/volume] in Serum or Plasma

2.20

1.87

4.7

2.9

0.84

0.83

mmol/l

0.15

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

132

2.00

1.75

3.4

2.0

2.57

3.07

mg/l

0.84

118

(3046870) Tissue transglutaminase IgG Ab [Units/volume] in Serum

3.36

1.70

1.0

1.3

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

3.77

1.64

1.0

4.1

0.00

g/l

—

(3029338) Protein.monoclonal band 3 [Mass/volume] in Serum or Plasma by Electrophoresis

3.77

1.64

1.0

4.1

0.00

g/l

—

(3014576) Chloride [Moles/volume] in Serum or Plasma

2.20

1.63

4.6

8.3

103.93

104.03

mmol/l

0.03

(3012516) Albumin [Mass/volume] in Urine

161

1.89

1.61

3.3

3.0

22.70

81.37

mg/l

1.60

101

(40760892) CBC W Ordered Manual Differential panel - Blood

145

1.90

1.57

4.3

4.4

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

3.51

1.55

1.0

4.1

0.00

g/l

—

(36660697) Celiac disease serology panel - Serum

2.65

1.55

1.2

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

2.13

1.53

2.6

2.9

0.57

3.53

e6/l

—

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

2.67

1.50

2.6

2.0

—

(3026008) Bacteria identified in Urine by Culture

166

1.81

1.44

2.9

3.5

—

(3020682) Albumin/Creatinine [Ratio] in Urine

166

1.81

1.44

4.2

3.6

4.29

12.86

mg/mmol

1.44

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

2.07

1.43

3.0

2.9

1.23

0.97

e6/l

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

2.24

1.42

1.4

2.6

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

109

1.90

1.37

1.4

1.2

16.29

21.39

iu/ml

—

(40768443) Skin Pathology biopsy report

2.64

1.33

1.3

1.1

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

2.23

1.30

1.2

2.4

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

112

1.83

1.25

3.0

2.4

—

(3004588) Protein electrophoresis panel - Serum or Plasma

2.40

1.14

1.0

3.5

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

2.37

1.05

1.8

2.3

—

(1761868) Lipid panel - Serum or Plasma

242

0.60

0.99

4.2

3.1

—

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

2.25

0.94

2.5

2.2

2.12

1.01

—

(3024889) Methemoglobin/Hemoglobin.total in Venous blood

2.25

0.94

2.5

2.1

0.63

0.69

—

(3018095) Leukocytes [#/volume] in Urine

193

1.57

0.94

4.3

3.7

29.37

93.23

e6/l

0.47

140

(3029937) Albumin [Presence] in Urine by Test strip

175

1.58

0.93

4.4

4.0

0.00

0.03

estimate

—

(3027945) Reticulocytes/Erythrocytes in Blood

1.89

0.89

2.3

4.6

2.06

2.04

—

(40768797) Stomach Pathology biopsy report

1.79

0.89

1.2

1.3

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

246

1.49

0.80

5.2

3.0

97.96

119.07

ug/l

0.50

231

(3036481) Cortisol [Moles/volume] in Serum or Plasma

1.79

0.77

2.5

2.2

619.10

403.16

nmol/l

—

(4034850) Laboratory test

2.17

0.76

16.4

9.8

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

2.08

0.74

1.8

2.3

—

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

1.92

0.70

4.0

14.3

25.00

24.89

mmol/l

—

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.78

0.65

1.2

1.4

—

(3003031) Transferrin.carbohydrate deficient.disialo/Transferrin.total in Serum or Plasma

1.61

0.61

1.8

1.6

1.45

1.25

0.45

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

1.64

0.56

1.8

1.4

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

554

1.61

0.54

33.8

18.3

3.97

3.98

mmol/l

0.06

543

(3045414) Leukocytes [Presence] in Urine

1.62

0.51

2.9

1.8

—

0.25

estimate

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

1.55

0.50

1.7

1.8

—

(40768804) Tissue Pathology biopsy report

224

1.35

0.50

1.7

2.0

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

168

1.37

0.48

3.1

3.4

1721.53

1525.56

ng/l

0.12

142

(3017732) Neutrophils [#/volume] in Blood

1.53

0.47

1.8

3.9

4.65

7.23

e9/l

—

(3019832) Treponema pallidum Ab [Presence] in Serum

1.45

0.47

1.6

2.0

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.42

0.0

1.3

—

(3003694) ABO and Rh group [Type] in Blood

153

1.34

0.42

1.3

1.5

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.51

0.41

1.8

1.6

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.41

0.0

1.0

—

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

1.44

0.41

1.3

1.6

—

(3000494) Fungus identified in Specimen by Culture

1.44

0.41

4.2

1.3

—

(3013512) EKG study

173

1.31

0.39

3.5

3.4

—

(3000991) Gas panel - Venous blood

1.51

0.37

5.2

9.4

—

(3042936) Bacteria identified in Isolate by Culture

1.39

0.37

6.2

2.2

—

(4010399) Spirometry for bronchospasm with prolonged evaluation after bronchodilator

1.43

0.36

1.7

1.4

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

554

1.39

0.32

34.3

18.3

139.53

139.64

mmol/l

0.10

546

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

0.68

0.28

1.4

1.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

1.32

0.26

1.7

1.8

—

(40761511) CBC panel - Blood by Automated count

559

1.31

0.23

29.1

14.3

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.21

0.22

2.2

1.6

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

0.21

0.0

1.3

—

(40763531) Fetal Nuchal fold [Multiple of the median] Thickness adjusted for maternal weight

0.00

0.21

0.0

1.3

—

0.81

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

0.00

0.21

0.0

1.4

—

16.24

—

(3000012) Reticulocyte production index

0.00

0.21

0.0

1.6

—

0.77

—

(46235831) Pregnancy associated plasma protein A [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.3

—

0.92

—

(3008714) Choriogonadotropin [Multiple of the median] adjusted in Serum or Plasma

0.00

0.21

0.0

1.3

—

1.12

—

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

3.5

—

11.41

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

0.21

0.0

1.6

—

(42529200) Cancer Ag 15-3 [Units/volume] in Serum or Plasma by Immunoassay

0.00

0.21

0.0

4.8

—

30.67

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

0.00

0.21

0.0

1.8

—

125.39

—

(3005785) Creatine kinase.MB [Mass/volume] in Serum or Plasma

1.27

0.21

1.5

2.1

3.53

6.19

ug/l

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

225

1.18

0.20

4.6

3.9

45.86

38.42

ng/l

0.10

139

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

355

1.17

0.19

3.1

3.2

—

(3000492) Spirometry study

0.75

0.18

1.2

1.4

—

(3002256) Pathology report gross observation

1.16

0.17

1.0

1.2

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

574

1.26

0.15

35.6

20.1

76.27

77.65

umol/l

0.16

569

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

1.16

0.08

1.0

1.7

—

(3007853) Bacteria identified in Skin by Aerobe culture

0.79

0.08

2.0

1.5

—

(3007461) Platelets [#/volume] in Blood

592

0.97

0.08

44.1

23.8

264.64

248.86

e9/l

1.03

585

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

576

1.23

0.07

17.2

11.4

25.53

25.14

u/l

0.06

569

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

1.10

0.07

1.9

1.6

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.04

0.00

1.8

2.3

—

(40764999) Glomerular filtration rate [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)/1.73 sq M

512

0.98

0.00

19.9

15.8

81.19

80.66

ml/min/173m2

0.05

481

(3013603) Prostate specific Ag [Mass/volume] in Serum or Plasma

158

1.02

0.00

4.5

5.1

1.45

4.02

ug/l

0.74

150

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

0.0

1.2

—

(3015956) Eosinophils/Leukocytes in Blood by Manual count

0.00

0.0

2.8

—

3.20

—

(3016038) Potassium [Moles/volume] in Urine

0.00

0.0

1.0

—

27.40

—

(3003329) Lymphocytes/Leukocytes in Synovial fluid

0.00

0.0

1.2

—

27.40

—

(40768441) Liver Pathology biopsy report

0.00

0.0

1.4

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.2

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

0.0

1.3

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(21494890) Protein electrophoresis panel - 24 hour Urine

0.00

0.0

2.2

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3006257) Acetylcholine receptor Ab [Moles/volume] in Serum

0.00

0.0

1.0

—

(3005570) Glucose [Moles/volume] in Urine

0.00

0.0

1.0

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.0

1.1

—

(3018333) Ribosomal P Ab [Presence] in Serum

0.00

0.0

1.2

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

0.00

0.0

3.2

—

(3017354) Segmented neutrophils/Leukocytes in Blood

0.00

0.0

2.2

—

83.20

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

(3014959) Toxoplasma gondii IgG Ab [Units/volume] in Serum

0.00

0.0

2.4

—

(40764126) Parainfluenza virus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3018301) Testosterone Free [Moles/volume] in Serum or Plasma

0.00

0.0

1.4

—

180.49

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.2

—

(44816808) CXCL13 Ag [Mass/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.2

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.2

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.2

—

(3000855) Microscopic observation [Identifier] in Vaginal fluid by Gram stain

0.00

0.0

2.8

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.0

1.2

—

(3017817) Protein [Mass] in Urine collected for unspecified duration

0.00

0.0

1.0

—

80.80

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

0.0

1.6

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

0.0

1.6

—

(3011391) Calcitriol [Moles/volume] in Serum or Plasma

0.00

0.0

1.2

—

100.60

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

0.85

-0.00

8.6

8.4

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

1.5

—

(3028271) Lactate [Moles/volume] in Capillary blood

0.00

-0.00

0.0

1.7

—

1.24

—

(3040363) Hepatitis A virus IgG Ab [Presence] in Serum by Immunoassay

0.00

-0.00

0.0

1.0

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

-0.00

0.0

1.5

—

(3012441) Differential panel - Pleural fluid

0.00

-0.00

0.0

2.0

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3029080) Hemoglobin [Entitic mass] in Reticulocytes

0.00

-0.00

0.0

1.3

—

32.43

—

(40768795) Lymph node Pathology biopsy report

0.00

-0.00

0.0

1.0

—

(1617658) Protocol used for examination of sentinel lymph nodes

0.00

-0.00

0.0

1.0

—

(3042631) Mycobacterium sp identified in Specimen

0.00

-0.00

0.0

2.2

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

-0.00

0.0

1.3

—

(3026725) Estradiol (E2) [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

1.7

—

0.32

—

(3047826) Mullerian inhibiting substance [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.8

—

1.31

—

(44816752) ERBB2 gene copy number/nucleus in Tissue by FISH

0.00

-0.00

0.0

1.2

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

-0.00

0.0

1.2

—

(3003191) Choriogonadotropin [Presence] in Serum or Plasma

0.00

-0.00

0.0

2.0

—

(4035726) Immunohistochemistry procedure

1.00

-0.00

1.0

1.4

—

(3027544) Mycobacterium sp identified in Sputum by Organism specific culture

0.00

-0.00

0.0

2.2

—

(3022806) Fractional oxyhemoglobin in Capillary blood

0.00

-0.00

0.0

1.5

—

89.82

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

1.9

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.0

—

(4281824) Cell count and differential, peritoneal fluid

0.00

-0.00

0.0

1.1

—

(40759850) Jo-1 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

-0.00

0.0

1.2

—

(40762119) U1 small nuclear ribonucleoprotein 70kD Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(44806420) Estimation of glomerular filtration rate

0.00

-0.00

0.0

1.7

—

Mortality – FinRegistry

↥

Association

Association between endpoint G6_THROOT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have G6_THROOT.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: G6_THROOT – Thoracic root disorders

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Thoracic root disorders

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

Matched cohort

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints