Kaposi sarcoma, including Hilmo

C3_KAPOSI_SARCOMA_WIDE

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 C46
  • Cause of death: ICD-10 C46

2 out of 7 registries used, show all original rules.

67

4. Check minimum number of events

None

67

5. Include endpoints

None

67

6. Filter based on genotype QC (FinnGen only)

54

Control definitions (FinnGen only)

Control exclude
C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze
DF12
Parent code in ICD-10
C45-C49
Name in latin
Sarcoma Kaposi

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

All Female Male
Number of individuals 54 13 41
Unadjusted period prevalence (%) 0.02 0.00 0.02
Median age at first event (years) 73.32 67.62 75.13

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
62
Matched controls
620
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
C46.0
ICD-10 Finland
Kaposi sarcoma of skin
+∞
48.4
40
*
9140/3-C44.7
ICD-O-3
Kaposi sarcoma of skin of lower limb and hip
+∞
24.6
22
*
C46.9
ICD-10 Finland
Kaposi sarcoma, unspecified
+∞
12.9
12
*
WF004
NOMESCO Finland
Palliative radiotherapy
+∞
11.8
11
*
TQX10
NOMESCO Finland
Biopsy of skin and subcutaneous tissue
16.3
11.2
18
15
QDE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in lower limb
43.7
9.4
11
*
QAE10
NOMESCO Finland
Excision of other lesion extending through all layers of skin in head or neck
24.3
8.9
12
6
117
Kela drug reimbursment
Leukaemia and other malignant diseases of the blood and bone marrow, and malignant diseases of the lymphatic tissue
+∞
8.5
8
*
ZX012
NOMESCO Finland
Radiotherapy with large shaped fields - isocentric therapy
+∞
8.5
8
*
8140/3-C61.9
ICD-O-3
Adenocarcinoma, NOS, of prostate gland
+∞
7.4
7
*
C61
ICD-10 Finland
Malignant neoplasm of prostate
+∞
7.4
7
*
D48.5
ICD-10 Finland
Neoplasm of uncertain or unknown behaviour: Skin
16.3
7.2
11
8
WZC00
NOMESCO Finland
Treatment plan or consultation
4.2
6.6
24
81
B23.1
ICD-10 Finland
HIV disease resulting in (persistent) generalized lymphadenopathy
77.5
6.6
7
*
WF049
NOMESCO Finland
Radiotherapy of metastasis
77.5
6.6
7
*
PJA12
NOMESCO Finland
Sentinel node biopsy
+∞
6.3
6
*
9140/3-C44.9
ICD-O-3
Kaposi sarcoma of skin, NOS
+∞
6.3
6
*
WD105
NOMESCO Finland
Cystostatic therapy of methastized malignancy
+∞
6.3
6
*
C46.3
ICD-10 Finland
Kaposi sarcoma of lymph nodes
+∞
6.3
6
*
YN1BD
NOMESCO Finland
Extensive CT examination of extremities for dose design of radiotherapy
+∞
6.3
6
*
WF002
NOMESCO Finland
Radical radiotherapy
+∞
6.3
6
*
8090/3-C44.9
ICD-O-3
Basal cell carcinoma, NOS, of skin, NOS
+∞
6.3
6
*
C46.7
ICD-10 Finland
Kaposi sarcoma of other sites
+∞
6.3
6
*
130
Kela drug reimbursment
Malignant tumour
+∞
6.3
6
*
A04AA02
ATC
granisetron; systemic, transdermal
+∞
6.3
6
*
J01MA12
ATC
levofloxacin; systemic
4.2
6.0
21
68

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
19
8
33.35
14.89
2.2
1.3
—
—
—
0
0
32
106
5.17
9.48
3.9
1.5
—
—
—
0
0
18
35
6.80
7.03
1.8
1.4
—
—
—
0
0
17
31
7.14
6.95
2.4
1.1
—
—
—
0
0
12
14
10.31
6.40
4.9
1.6
—
—
—
0
0
17
48
4.50
5.81
1.7
2.0
—
—
—
0
0
10
10
11.64
5.77
2.0
1.2
—
—
—
0
0
5
0
+∞
5.27
1.6
0.0
—
—
—
0
0
12
22
6.49
4.90
5.5
1.5
—
—
—
0
0
31
157
2.95
4.19
5.2
3.9
27.48
92.17
e6/l
0.64
24
114
34
184
2.88
4.03
17.3
4.9
26.67
25.63
%
0.19
34
172
11
24
5.33
3.97
1.7
1.4
—
—
—
0
0
29
147
2.83
3.85
3.7
3.2
14.17
487.72
e6/l
0.53
23
110
13
42
3.65
3.61
2.5
1.6
—
—
—
0
0
15
54
3.35
3.55
1.1
1.2
—
—
—
0
0
16
61
3.19
3.46
2.3
1.8
—
—
—
0
0
9
19
5.35
3.38
9.7
2.5
305.56
263.75
mg/l
—
9
8
25
124
2.70
3.38
5.0
2.0
—
—
—
0
0
16
62
3.13
3.36
13.2
5.5
0.92
1.09
mmol/l
1.42
16
57
26
136
2.57
3.13
5.3
4.5
—
—
—
0
0
24
121
2.60
3.11
3.1
3.0
0.01
0.35
e6/l
2.13
18
85
5
5
10.71
3.03
1.0
1.2
7.82
14.56
mg/l
—
5
5
25
131
2.52
2.97
13.3
4.5
—
—
—
0
0
32
189
2.43
2.93
15.0
4.5
58.93
59.61
%
0.12
32
177
30
173
2.42
2.89
4.9
3.4
6.62
6.02
ph
2.31
17
95
23
118
2.51
2.84
3.2
3.7
7.39
7.40
ph
0.21
17
86
5
6
8.92
2.80
1.6
1.2
—
—
—
0
0
5
6
8.92
2.80
5.6
3.8
12.52
10.88
mg/l
—
5
6
8
19
4.67
2.78
1.6
1.1
—
—
—
0
0
35
222
2.32
2.66
16.0
3.1
10.53
13.81
umol/l
1.33
35
211
33
214
2.16
2.27
5.3
3.6
0.00
0.00
estimate
—
7
49
8
24
3.67
2.27
1.6
1.8
60.26
65.74
g/l
—
8
18
33
215
2.14
2.23
8.6
6.1
1.19
1.21
mmol/l
0.54
28
184
27
164
2.14
2.17
6.6
2.3
—
—
estimate
—
0
0
33
220
2.07
2.06
5.6
3.7
0.00
0.00
estimate
—
9
47
13
60
2.48
1.94
3.5
2.7
24.92
21.19
%
0.23
13
55
32
216
2.00
1.88
5.7
3.6
0.00
0.00
estimate
—
9
50
33
226
1.98
1.85
33.6
19.2
1.38
1.43
inr
0.17
28
198
19
106
2.14
1.85
4.5
2.7
361.21
389.02
umol/l
0.65
19
89
19
108
2.09
1.76
13.9
3.7
—
—
—
0
0
8
31
2.81
1.73
2.9
4.8
62.37
90.87
ng/l
—
8
23
38
278
1.95
1.72
7.0
4.4
—
—
—
0
0
7
25
3.02
1.70
1.1
1.6
—
—
—
0
0
14
71
2.26
1.70
3.9
2.5
10.13
11.94
umol/l
0.41
14
66
13
65
2.27
1.63
3.8
2.5
2.13
2.19
g/l
0.09
13
58
6
21
3.05
1.54
5.7
1.6
0.51
1.29
ug/l
—
6
16
26
173
1.87
1.52
22.0
10.5
0.00
0.00
e9/l
0.09
20
139
7
28
2.69
1.50
3.9
2.8
—
—
—
0
0
29
205
1.78
1.37
1.9
2.2
84.02
88.47
pmol/l
0.23
18
99
8
35
2.47
1.32
1.6
1.4
—
—
—
0
0
5
18
2.93
1.31
6.0
3.6
—
—
—
0
0
5
19
2.77
1.24
1.2
1.2
—
—
—
0
0
12
71
1.86
0.97
14.2
3.0
—
—
—
0
0
18
122
1.67
0.94
4.5
3.5
0.00
0.00
estimate
—
7
40
6
29
2.18
0.92
6.0
4.4
—
—
—
0
0
8
44
1.94
0.90
2.8
7.2
111.50
122.84
g/l
—
8
44
15
98
1.70
0.89
1.3
1.2
—
—
—
0
0
19
138
1.54
0.74
2.4
1.8
50.58
90.47
u/l
0.61
19
129
22
167
1.49
0.70
7.8
3.8
—
—
—
0
0
19
141
1.50
0.67
3.0
3.7
—
—
—
0
0
17
131
1.41
0.49
6.6
3.2
0.00
0.00
estimate
—
6
35
18
143
1.36
0.43
4.4
3.3
—
—
—
0
0
46
426
1.31
0.34
37.6
20.3
138.89
139.83
mmol/l
1.51
46
415
20
167
1.29
0.34
5.9
3.5
0.00
0.00
estimate
—
7
36
46
428
1.29
0.31
37.6
20.2
4.00
4.03
mmol/l
0.26
46
417
8
64
1.29
0.29
4.5
5.4
103.00
104.73
mmol/l
—
8
64
48
451
1.28
0.28
52.1
22.6
131.27
136.26
g/l
1.11
48
441
47
443
1.25
0.25
44.2
21.0
83.94
88.94
umol/l
0.62
47
431
15
177
0.80
0.25
4.4
3.5
182.46
67.13
mg/l
—
10
118
19
165
1.22
0.23
2.1
2.2
142.47
646.52
u/l
0.61
19
156
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
0
10
0.00
0.21
0.0
1.4
—
—
—
0
0
0
10
0.00
0.21
0.0
1.2
—
—
—
0
0
6
47
1.31
0.21
4.5
3.0
3.27
2.13
mmol/l
—
6
34
6
48
1.28
0.21
4.5
3.1
7.40
7.37
ph
—
6
34
0
13
0.00
0.21
0.0
1.2
—
1.42
—
0
13
0
13
0.00
0.21
0.0
1.1
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
0.95
—
0
13
47
451
1.17
0.15
53.0
22.7
39.60
40.47
%
0.55
47
441
47
451
1.17
0.15
52.8
22.4
92.46
91.29
fl
0.91
47
441
47
451
1.17
0.15
52.7
22.4
30.72
30.40
pg
0.49
47
441
31
297
1.09
0.07
5.2
4.8
—
—
—
0
0
41
401
1.07
0.03
14.1
5.6
6.07
6.20
mmol/l
0.37
36
358
42
424
0.97
0.00
29.8
14.3
—
—
—
0
0
14
136
1.04
0.00
3.6
2.8
0.69
0.78
ug/l
—
9
83
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
117.38
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
11.04
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
7.8
—
22.16
—
0
5
0
5
0.00
-0.00
0.0
1.4
—
261.00
—
0
5
0
6
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.3
—
61.73
—
0
6
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0

Mortality – FinRegistry

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

Index endpoint: C3_KAPOSI_SARCOMA_WIDE – Kaposi sarcoma, including Hilmo

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).