Wilms' tumor, excluding all cancers (controls excluding all cancers)

C3_WILMS_TUMOR_EXALLC

No definition available.

Endpoint definition

↥

Endpoint definition steps	FinnGen
Phenotype data	520210
1. Apply sex-specific rule None	520210
2. Check conditions None	520210
3. Check pre-conditions, main-only, mode, registry filters Registry filters: Hospital discharge: ICD-10 — C64.80& Cause of death: ICD-10 — C64.80& 2 out of 7 registries used, show all original rules.	216
4. Check minimum number of events None	216
5. Include endpoints None	216
6. Filter based on genotype QC (FinnGen only)	216

Control definitions (FinnGen only)

Control exclude: C3_CANCER, C3_CANCER_WIDE

Extra metadata

First used in FinnGen datafreeze: DF12

NAME	C3_WILMS_TUMOR_EXALLC
CONTROL_EXCLUDE	C3_CANCER\|C3_CANCER_WIDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10	C6480
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10	C6480
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB
KELA_REIMB_ICD
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Wilms' tumor, excluding all cancers (controls excluding all cancers) based on the number of shared cases.

Similar with more cases:

Similar with less cases:

Wilms' tumor

Case counts by codes

↥

FinnGen case counts by registry codes:

Upset plot

Full data table

Summary Statistics

↥

-FinRegistry-

This endpoint is excluded (different definition than used in FinnGen).

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	216	78	138
Unadjusted period prevalence (%)	0.05	0.03	0.06
Median age at first event (years)	62.86	58.22	65.48

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

No data

CodeWAS (R11)

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3003458) Phosphate [Moles/volume] in Serum or Plasma

242

3.19

12.33

12.3

6.3

1.19

1.11

mmol/l

1.10

220

(3003785) Carcinoembryonic Ag [Mass/volume] in Serum or Plasma

4.20

9.86

1.6

1.4

3.26

6.70

ug/l

0.41

(3023323) Follitropin [Units/volume] in Serum or Plasma

6.93

9.48

3.1

1.8

26.46

12.39

iu/l

—

(3028531) Enolase.neuron specific [Mass/volume] in Serum or Plasma

9.02

9.43

6.0

1.4

29.23

16.95

ug/l

0.69

(4035726)

3.97

7.10

1.4

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

5.13

7.04

1.3

—

(3051552) Clostridioides difficile toxin genes [Presence] in Stool by NAA with probe detection

100

3.19

6.89

1.4

1.7

—

(3009214) Lutropin [Units/volume] in Serum or Plasma

4.72

6.83

2.8

1.5

16.77

5.03

u/l

—

(3029287) Urinalysis microscopic panel [#/volume] - Urine by Automated count

564

2.14

6.77

5.8

3.6

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

101

633

2.12

6.74

8.5

4.4

34.18

35.08

g/l

1.04

584

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

337

2.28

6.59

3.8

1.9

—

(3000991) Gas panel - Venous blood

171

2.64

6.46

11.0

7.1

—

(3002032) Base excess in Venous blood by calculation

213

2.47

6.30

10.0

4.4

0.21

1.67

mmol/l

2.11

162

(3021447) Carbon dioxide [Partial pressure] in Venous blood

212

2.42

5.92

10.3

4.4

5.51

5.75

kpa

1.05

206

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

631

2.01

5.87

6.1

3.5

—

(3044640) Blood type and Crossmatch panel - Blood

439

2.09

5.83

4.1

2.0

—

(3021901) Oxygen saturation in Capillary blood

4.06

5.36

4.6

3.5

—

(3018095) Leukocytes [#/volume] in Urine

580

1.91

4.95

6.0

4.3

29.05

130.18

e6/l

2.74

411

(3016431) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Serum or Plasma

110

779

1.84

4.63

17.0

6.2

1.23

1.21

mmol/l

1.25

105

664

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

4.58

4.62

1.4

1.2

—

(3030467) Casts [#/volume] in Urine by Automated count

463

1.91

4.60

5.3

3.6

0.14

0.45

e6/l

2.67

344

(40763571) Iron/Transferrin [Ratio] in Serum or Plasma

218

2.15

4.35

6.1

2.7

22.47

22.72

0.04

196

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

4.04

4.32

1.3

1.4

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

136

2.40

4.26

2.1

1.4

—

(44790047)

7.17

4.20

1.3

1.2

—

(44790048)

7.17

4.20

1.3

1.2

—

(44790049)

7.17

4.20

1.3

1.2

—

(44806118)

7.17

4.20

1.3

1.2

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

6.65

4.02

7.4

6.1

10.73

11.02

mg/l

—

(3046279) Procalcitonin [Mass/volume] in Serum or Plasma

3.04

4.00

2.2

1.8

3.05

2.76

ug/l

0.06

(3018418) pH of Serum or Plasma

414

1.86

3.99

11.9

3.4

7.38

7.40

—

(3052851) Hemolysis interference index of Serum or Plasma

3.15

3.77

6.5

3.4

—

(3013650) Neutrophils [#/volume] in Blood by Automated count

113

841

1.72

3.76

19.0

5.6

3.97

4.40

e9/l

1.17

106

716

(3020427) Coagulation factor X inhibitor [Units/volume] in Platelet poor plasma by Coagulation assay

3.09

3.65

2.9

2.7

0.30

0.33

u/ml

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

3.09

3.65

1.1

1.5

—

(3024354) Oxygen [Partial pressure] in Venous blood

181

2.11

3.65

10.0

4.0

5.54

4.73

kpa

0.85

174

(3044938) Influenza virus A RNA [Presence] in Specimen by NAA with probe detection

264

1.94

3.61

2.2

1.7

—

(3023368) Bacteria identified in Blood by Culture

435

1.78

3.58

6.5

3.7

—

(3018251) Fasting glucose [Moles/volume] in Serum or Plasma

116

1432

0.59

3.54

3.9

4.7

5.82

6.08

mmol/l

1.30

109

1273

(40761511) CBC panel - Blood by Automated count

134

1592

0.58

3.48

31.6

12.4

—

(3043924) Respiratory syncytial virus RNA [Identifier] in Specimen by NAA with probe detection

185

2.06

3.45

1.8

1.7

—

(3038288) Influenza virus B RNA [Presence] in Specimen by NAA with probe detection

185

2.06

3.45

1.8

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

5.89

3.37

1.5

1.3

—

(36304419) Bacteria [Presence] in Urine

434

1.75

3.35

5.4

3.5

—

(3026008) Bacteria identified in Urine by Culture

471

1.72

3.26

3.6

3.1

—

(3018677) aPTT in Platelet poor plasma by Coagulation assay

269

1.85

3.11

2.4

1.9

29.27

29.25

0.01

259

(3023520) Reticulocytes [#/volume] in Blood

153

2.03

2.87

2.6

2.3

59.19

62.44

e9/l

0.27

123

(43055554) Base excess.100% oxygenated [Moles/volume] standard in Capillary blood by calculation

168

1.99

2.86

6.5

1.98

1.66

mmol/l

0.19

115

(40768441) Liver Pathology biopsy report

8.49

2.76

1.2

1.0

—

(21493690) Lymphocyte T-cell and B-cell and Natural killer subsets panel - Blood

6.13

2.71

6.7

3.5

—

(40764999) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (CKD-EPI)

108

1317

0.64

2.66

29.4

12.5

62.90

75.47

ml/min/173m2

3.98

1043

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

188

1.89

2.64

2.1

1.6

—

(3030692) Respiratory virus DNA+RNA [Identifier] in Specimen by NAA with probe detection

4.11

2.59

1.5

1.2

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

4.48

2.49

1.1

1.3

—

(21494815) CD4 cells/100 lymphocytes in Specimen

5.11

2.42

5.7

2.8

—

(40758558) Short blood count panel - Blood

365

1.64

2.41

18.0

4.9

—

(46236952) Glomerular filtration rate/1.73 sq M.predicted [Volume Rate/Area] in Serum, Plasma or Blood by Creatinine-based formula (MDRD)

105

2.11

2.40

4.8

2.2

53.40

57.52

ml/min/173m2

—

(3002256) Pathology report gross observation

101

2.08

2.24

1.3

1.1

—

(3020630) Protein [Mass/volume] in Serum or Plasma

123

1.97

2.21

4.7

1.9

65.07

67.09

g/l

0.52

106

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

3.58

2.07

1.0

1.3

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

4.08

2.05

1.3

1.4

—

(3008757) Leukocyte morphology finding [Identifier] in Blood

4.08

2.05

1.5

3.9

—

(3024891) Influenza virus A+B Ag [Presence] in Specimen

2.58

2.04

1.4

1.2

—

(3042936) Bacteria identified in Isolate by Culture

212

1.72

2.04

2.1

1.7

—

(3019900) Cholesterol [Moles/volume] in Serum or Plasma

121

1408

0.68

2.04

4.4

4.6

4.45

4.37

mmol/l

0.36

116

1286

(40762366) Oxygen capacity [Volume Fraction] in Arterial blood

2.14

1.96

6.0

7.6

—

(3048773) Triglyceride [Moles/volume] in Serum or Plasma --fasting

115

1346

0.69

1.95

4.4

4.2

1.40

1.23

mmol/l

1.61

110

1210

(3037756) Immunofixation for Serum or Plasma

3.04

1.95

1.0

1.2

—

(3040359) Human coronavirus NL63 RNA [Presence] in Specimen by NAA with probe detection

3.82

1.95

1.2

1.1

—

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

3.82

1.95

1.0

1.3

—

(3041642) Human coronavirus 229E RNA [Presence] in Specimen by NAA with probe detection

3.82

1.95

1.2

1.1

—

(3038546) Human coronavirus OC43 RNA [Presence] in Specimen by NAA with probe detection

3.82

1.95

1.2

1.1

—

(3004410) Hemoglobin A1c/Hemoglobin.total in Blood

118

1374

0.69

1.94

6.3

6.6

41.98

40.98

mmol/mol

0.32

113

1261

(3009201) Thyrotropin [Units/volume] in Serum or Plasma

119

1383

0.69

1.93

7.4

4.4

2.04

2.00

mu/l

0.11

114

1233

(40760888) Immunoglobulin light chains.free panel - Serum

3.25

1.89

2.4

1.3

—

(3035637) Corticotropin [Mass/volume] in Plasma

2.93

1.88

1.4

1.6

—

(40768804) Tissue Pathology biopsy report

432

1.50

1.84

2.3

1.5

—

(43055120) Cytomegalovirus DNA [Units/volume] (viral load) in Serum or Plasma by NAA with probe detection

3.11

1.81

4.0

9.4

—

797.83

—

(3006923) Alanine aminotransferase [Enzymatic activity/volume] in Serum or Plasma

143

1599

0.69

1.78

20.6

8.6

33.96

24.71

u/l

0.54

137

1515

(3007853) Bacteria identified in Skin by Aerobe culture

197

1.67

1.75

2.0

1.7

—

(3046524) Influenza virus A Ag [Presence] in Nasopharynx by Immunoassay

2.45

1.70

1.6

1.3

—

(3043362) Influenza virus B Ag [Presence] in Nasopharynx by Immunoassay

2.45

1.70

1.6

1.3

—

(3003396) Base excess in Arterial blood by calculation

191

1.66

1.68

4.4

5.3

-0.28

1.47

mmol/l

0.96

146

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

3.22

1.67

2.0

1.5

—

nmol/l

—

(3032155) Metanephrine Free [Moles/volume] in Serum or Plasma

3.22

1.67

2.2

1.5

—

(40760892) CBC W Ordered Manual Differential panel - Blood

284

1.55

1.64

5.7

3.9

—

(3032080) INR in Blood by Coagulation assay

644

1.41

1.62

12.0

9.9

1.35

1.40

inr

0.13

167

(3022313) Gas panel - Capillary blood

138

1.75

1.59

6.3

6.6

—

(3036481) Cortisol [Moles/volume] in Serum or Plasma

154

1.70

1.58

3.1

2.1

362.68

356.50

nmol/l

0.06

135

(3021879) Hepatitis B virus core Ab [Presence] in Serum

1.97

1.53

1.4

1.3

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

113

958

1.38

1.52

6.9

4.4

6.90

6.77

mmol/l

0.22

108

889

(3026179) Normetanephrine [Moles/volume] in Serum or Plasma

2.91

1.51

2.2

1.5

0.57

0.48

nmol/l

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

2.43

1.47

2.1

1.3

70.23

35.56

mg/l

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

2.43

1.47

2.1

1.3

82.68

55.77

mg/l

—

(3023103) Potassium [Moles/volume] in Serum or Plasma

145

1600

0.71

1.47

39.7

16.7

4.18

4.01

mmol/l

8.32

139

1544

(3027801) Oxygen [Partial pressure] in Arterial blood

190

1.61

1.47

4.5

5.3

12.39

11.46

kpa

0.23

182

(3027946) Carbon dioxide [Partial pressure] in Arterial blood

190

1.61

1.47

4.5

5.3

4.70

5.06

kpa

1.44

182

(3010517) Carboxyhemoglobin/Hemoglobin.total in Venous blood

1.88

1.46

7.6

2.3

1.24

1.10

0.39

(3051611) Lipemic interference index of Serum or Plasma

2.77

1.44

9.8

2.4

—

(3019550) Sodium [Moles/volume] in Serum or Plasma

145

1597

0.72

1.42

39.2

16.6

139.06

139.66

mmol/l

1.93

139

1540

(3006418) Campylobacter sp identified in Tissue by Organism specific culture

2.23

1.42

1.0

1.2

—

(3019198) Lymphocytes [#/volume] in Blood

772

1.36

1.40

11.1

5.2

1.84

1.97

e9/l

0.82

663

(3021337) Troponin I.cardiac [Mass/volume] in Serum or Plasma

347

1.45

1.39

5.4

3.9

168.02

349.82

ng/l

0.60

286

(1761868) Lipid panel - Serum or Plasma

430

0.65

1.39

2.7

3.3

—

(3013327) Hepatitis A virus IgM Ab [Presence] in Serum

2.98

1.36

1.0

—

(3014765) Yersinia sp identified in Stool by Organism specific culture

2.18

1.36

1.0

1.2

—

(3006315) Basophils [#/volume] in Blood

756

1.35

10.7

5.2

0.04

e9/l

0.62

639

(42870588) Differential panel, method unspecified - Blood

521

1.38

1.35

10.5

5.6

—

(3022217) INR in Platelet poor plasma by Coagulation assay

246

1.50

1.32

21.4

27.4

1.54

1.31

inr

0.44

(36305247) Microscopic observation [Identifier] in Isolate by Gram stain

2.40

1.30

1.8

1.2

—

(3008152) Bicarbonate [Moles/volume] in Arterial blood

115

1.72

1.30

2.5

5.4

22.88

24.33

mmol/l

0.89

107

(3051651) Icteric interference index of Serum or Plasma

2.82

1.29

11.2

1.8

—

(3001604) Monocytes [#/volume] in Blood

752

1.34

1.27

10.8

5.2

0.64

0.61

e9/l

0.29

629

(3044889) 12 lead EKG panel

1014

0.75

1.27

4.3

4.1

—

(3026989) Triiodothyronine (T3) Free [Moles/volume] in Serum or Plasma

1.91

1.27

5.1

3.1

4.19

4.66

pmol/l

0.74

(43054914) Glucose tolerance 2 hours panel - Serum or Plasma

167

0.52

1.25

1.3

1.7

—

(42529406) Shigella sp [Presence] in Stool by Culture

2.09

1.24

1.0

1.2

—

(3013115) Eosinophils [#/volume] in Blood

785

1.32

1.22

12.9

5.2

0.27

0.21

e9/l

0.85

670

(3037467) Urinalysis macro (dipstick) panel - Urine

121

1060

1.32

1.22

7.3

4.3

—

(40761536) Microorganisms panel - Urine sediment

114

0.43

1.16

18.4

4.0

—

(3020460) C reactive protein [Mass/volume] in Serum or Plasma

142

1551

0.75

1.14

33.2

13.5

29.02

25.41

mg/l

0.66

128

1194

(3030306) Epithelial cells.non-squamous [#/volume] in Urine by Automated count

290

1.42

1.12

4.1

3.2

1.05

1.00

e6/l

0.04

171

(3010566) Parathyrin.intact [Moles/volume] in Serum or Plasma

2.30

1.04

16.6

5.3

—

(3019060) Gas panel - Arterial blood

115

1.62

1.03

1.9

3.9

—

(3019225) pH of Specimen

141

1.54

0.99

8.9

3.2

—

(3050238) Crystals [Presence] in Synovial fluid by Light microscopy

1.98

0.98

1.1

1.2

—

(3019832) Treponema pallidum Ab [Presence] in Serum

143

0.54

0.97

1.5

1.6

—

(3019150) Specific gravity of Urine by Refractometry

343

1.36

0.97

6.7

4.1

1.01

1.02

kg/l

1.96

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

0.96

0.0

1.5

—

(3005013) Prostate Specific Ag Free [Mass/volume] in Serum or Plasma

365

0.70

0.93

2.7

2.6

0.72

0.77

ug/l

0.16

254

(1616796) Gas panel - Central venous blood

2.17

0.92

14.0

4.9

—

(3009542) Hematocrit [Volume Fraction] of Blood

128

1393

0.80

0.84

35.0

14.7

35.55

39.17

2.59

947

(3004716) Salmonella sp identified in Stool by Organism specific culture

1.66

0.80

1.1

1.4

—

(3049717) Cytology report of Urine Cyto stain

1.69

0.79

2.3

1.8

—

(3020148) Glutamate decarboxylase 65 Ab [Units/volume] in Serum

0.00

0.78

0.0

1.1

—

39.14

—

(46237023) Hepatitis B virus core and surface Ab and surface Ag panel - Serum

1.79

0.77

1.7

1.2

—

(3025941) Bacteria identified in Stool by Culture

1.68

0.76

1.0

1.3

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.76

0.0

1.6

—

(36660697) Celiac disease serology panel - Serum

132

0.59

0.76

1.3

1.2

—

(3032035) Polymorphonuclear cells/100 leukocytes in Blood

2.11

0.75

5.0

3.4

53.00

59.79

—

(3030905) Polymorphonuclear cells [#/volume] in Blood

2.11

0.75

4.4

2.6

3.94

4.87

e9/l

—

(3000492) Spirometry study

106

0.55

0.74

1.0

1.3

—

(3015736) pH of Urine

593

1.24

0.73

6.1

3.7

—

(3005895) Myoglobin [Mass/volume] in Serum or Plasma

1.65

0.73

1.4

2.2

295.09

964.82

ug/l

0.50

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

203

0.67

0.71

1.5

1.3

34.33

14.06

u/ml

—

(37019628) Gastrointestinal bacterial pathogens panel - Stool by NAA with probe detection

1.94

0.71

1.2

—

(40768797) Stomach Pathology biopsy report

191

0.66

0.70

1.2

—

(3013512) EKG study

454

1.25

0.69

5.1

4.2

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

1.87

0.69

1.0

1.2

—

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

685

0.81

0.68

1.9

2.0

95.89

92.29

pmol/l

0.28

350

(3035285) Chloride [Moles/volume] in Venous blood

1.74

0.64

2.8

2.1

109.20

106.07

mmol/l

—

(3041354) Potassium [Moles/volume] in Venous blood

1.74

0.64

2.8

2.1

4.34

4.09

mmol/l

—

(3033705) Calcium.ionized [Moles/volume] in Venous blood

1.74

0.64

2.8

2.1

—

(4010399)

104

0.56

0.63

1.0

1.3

—

(3019800) Troponin T.cardiac [Mass/volume] in Serum or Plasma

649

0.81

0.63

6.3

4.0

62.19

100.77

ng/l

0.34

479

(3019230) Fractional oxyhemoglobin in Venous blood

1.68

0.62

13.4

2.2

65.60

62.25

—

(1761482) Bacteria [#/volume] in Urine by Culture

1.56

0.60

4.9

3.6

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

251

0.73

0.59

1.7

1.8

—

(3029879) Epithelial cells.squamous [#/volume] in Urine by Automated count

286

1.27

0.57

4.3

3.4

0.97

1.97

e6/l

0.95

166

(3016251) Hemoglobin.gastrointestinal [Presence] in Stool

0.56

0.57

2.8

2.6

—

(3008898) HLA-B27 [Presence]

1.69

0.57

1.0

1.1

—

(3001784) Prostate Specific Ag Free/Prostate specific Ag.total in Serum or Plasma

538

0.82

0.56

4.5

3.8

20.72

24.95

1.49

260

(3017181) Myelocytes/100 leukocytes in Blood

1.44

0.55

2.4

3.9

0.29

0.62

—

(3051714) Fibrin D-dimer FEU [Mass/volume] in Platelet poor plasma

306

1.25

0.55

2.1

1.7

1.08

1.26

mg/l

0.38

237

(40761535) Cells panel - Urine sediment

126

1.38

0.53

5.7

3.1

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

1.45

0.53

1.1

1.2

—

(21494755) Public health laboratory ask at order entry panel

0.59

0.46

1.2

1.4

—

(3002179) Metamyelocytes/100 leukocytes in Blood

1.42

0.45

2.5

4.2

0.60

0.21

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

1.41

0.45

2.9

3.8

—

(3017918) Cytomegalovirus IgG Ab [Titer] in Serum or Plasma

1.63

0.43

2.8

1.6

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

1.63

0.43

1.0

1.3

—

(3029937) Albumin [Presence] in Urine by Test strip

388

0.82

0.43

9.9

4.1

0.00

estimate

—

106

(46235759) Influenza virus B RNA [Presence] in Nasopharynx by NAA with probe detection

1.45

0.42

2.9

1.5

—

(3015635) Cytomegalovirus IgM Ab [Units/volume] in Serum or Plasma

1.58

0.42

2.8

1.6

—

(3019050) Tissue transglutaminase IgA Ab [Units/volume] in Serum

334

0.81

0.42

1.3

0.71

2.36

u/ml

—

(3023420) DNA double strand Ab [Units/volume] in Serum

0.00

0.41

0.0

1.3

—

(3016914) Bacteria identified in Cerebral spinal fluid by Culture

0.00

0.41

0.0

1.3

—

(3027529) Toxoplasma gondii IgM Ab [Units/volume] in Serum

0.00

0.41

0.0

1.3

—

(3010380) Borrelia burgdorferi IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.41

0.0

1.2

—

(3023430) Cat dander IgE Ab [Units/volume] in Serum

0.00

0.40

0.0

1.3

—

5.14

—

(3005136) Cladosporium herbarum IgE Ab [Units/volume] in Serum

0.00

0.39

0.0

1.2

—

0.16

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

0.39

0.0

1.0

—

(3014133) Dog dander IgE Ab [Units/volume] in Serum

0.00

0.39

0.0

1.3

—

3.94

—

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

549

1.15

0.39

3.7

3.4

3249.67

1876.20

ng/l

1.13

471

(3021589) Normoblasts [#/volume] in Blood

684

0.87

0.38

22.6

8.1

0.00

e9/l

0.74

531

(3044254) Respiratory syncytial virus RNA [Presence] in Specimen by NAA with probe detection

1.36

0.38

2.9

1.4

—

(3004490) Bicarbonate [Moles/volume] standard in Capillary blood

125

1.30

0.38

7.9

7.3

24.70

24.59

mmol/l

0.07

120

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.41

0.37

1.0

1.2

7.94

7.78

g/l

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.41

0.37

1.0

1.2

3.26

3.78

g/l

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

1.41

0.37

1.0

1.2

—

(3023183) Ammonium ion [Moles/volume] in Plasma

1.37

0.34

2.3

1.6

28.00

34.26

umol/l

—

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

890

0.89

0.33

3.6

3.0

—

(3011371) Neisseria gonorrhoeae DNA [Presence] in Specimen by NAA with probe detection

1.30

0.28

1.0

2.0

—

(3009508) Creatinine [Moles/volume] in Urine

513

1.12

0.28

4.1

3.6

5.92

7.47

mmol/l

2.66

424

(3013707) Erythrocyte sedimentation rate by Westergren method

118

1127

1.10

0.27

6.1

4.2

15.49

12.75

mm/h

0.91

112

1016

(3021584) Pregnancy associated plasma protein A [Units/volume] in Serum or Plasma

0.70

0.26

1.6

1.5

—

(3020891) Body temperature

1.26

0.26

8.8

3.3

—

(3006093) Chlamydia trachomatis DNA [Presence] in Specimen by NAA with probe detection

1.21

0.25

1.4

2.2

—

(3000330) Specific gravity of Urine by Test strip

1.26

0.25

4.8

3.2

—

(3021614) Rheumatoid factor [Units/volume] in Serum or Plasma

221

0.85

0.23

1.3

20.93

33.18

iu/ml

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

558

1.10

0.23

7.6

3.9

—

(3024928) Oxygen saturation in Venous blood

1.29

0.23

13.4

2.6

—

(3006184) Hemoglobin [Mass/volume] in Capillary blood

1.19

0.21

8.0

2.0

123.60

130.13

g/l

—

(3016894) Varicella zoster virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.21

0.0

1.1

—

(40759883) Oligoclonal Bands IgG [Presence] in Cerebral spinal fluid by Isoelectric focusing

0.00

0.21

0.0

1.0

—

(1001509) Gas and Carbon monoxide and Electrolytes panel - Arterial blood

0.00

0.21

0.0

1.5

—

(3021236) Streptolysin O Ab [Units/volume] in Serum or Plasma

0.00

0.21

0.0

1.2

—

105.36

—

(3008733) Herpes simplex virus DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.21

0.0

1.1

—

(40759849) Smith extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(3027231) Wheat IgE Ab [Units/volume] in Serum

0.00

0.21

0.0

1.5

—

(40759844) Sjogrens syndrome-B extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(40759842) Ribonucleoprotein extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(40759812) SCL-70 extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(40759836) Histone Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(3026515) Parvovirus B19 IgM Ab [Units/volume] in Serum

0.00

0.21

0.0

1.2

—

(42868414) European tick borne encephalitis virus IgM Ab [Presence] in Serum by Immunoassay

0.00

0.21

0.0

1.4

—

(40759843) Sjogrens syndrome-A extractable nuclear Ab [Presence] in Serum by Immunoblot

0.00

0.21

0.0

1.2

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

134

0.81

0.21

1.8

2.3

—

(3013005) Retinol [Moles/volume] in Serum or Plasma

0.00

0.21

0.0

1.9

—

1.85

—

(3025018) Bordetella pertussis Ab [Titer] in Serum

0.00

0.21

0.0

1.3

—

(4027681)

0.00

0.21

0.0

1.2

—

(3002434) Lupus erythematosus deoxynucleoproteins IgG Ab [Units/volume] in Serum by Immunoassay

1.17

0.21

1.2

1.7

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

123

0.80

0.21

1.6

2.1

—

(4146454)

0.00

0.21

0.0

3.5

—

(3017569) Oxygen content in Arterial blood

0.00

0.20

0.0

2.1

—

(3000208) Alpha tocopherol [Moles/volume] in Serum or Plasma

0.00

0.20

0.0

1.4

—

27.43

—

(3050449) Albumin [Mass/time] in Urine collected for unspecified duration

1.18

0.19

1.5

2.5

332.50

79.80

ug/min

—

(3003327) Ova and parasites identified in Stool by Light microscopy

1.18

0.19

1.3

1.5

—

(3034780) Angiotensin converting enzyme [Enzymatic activity/volume] in Serum or Plasma

1.14

0.19

1.2

2.0

36.78

38.98

u/l

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

376

1.08

0.12

6.6

3.8

—

(43534045) MCM6 gene c.-13910C>T and -13915T>G [Identifier] in Blood or Tissue by Molecular genetics method Nominal

1.17

0.11

1.2

1.1

—

(36031861) Influenza virus A and B and SARS-CoV-2 (COVID-19) and Respiratory syncytial virus RNA panel - Respiratory system specimen by NAA with probe detection

1.15

0.10

1.3

1.6

—

(3004588) Protein electrophoresis panel - Serum or Plasma

106

1.14

0.10

2.3

1.3

—

(3022621) pH of Urine by Test strip

106

1.14

0.10

3.6

2.4

—

(3016879) Cocaine [Presence] in Urine

1.14

0.10

1.0

1.2

—

(3000764) Benzodiazepines [Presence] in Urine

1.04

0.09

1.0

1.2

—

(3028300) Cannabinoids [Presence] in Urine

1.04

0.09

1.0

1.2

—

(3027944) Amphetamines [Presence] in Urine

1.04

0.09

1.0

1.2

—

(3027008) Opiates [Presence] in Urine

1.04

0.09

1.0

1.2

—

(3003694) ABO and Rh group [Type] in Blood

381

1.06

0.09

1.4

—

(3025159) Blasts/100 leukocytes in Blood

1.14

0.08

2.8

4.0

0.00

—

(3033319) Streptococcus pyogenes Ag [Presence] in Throat

137

1.10

0.07

2.1

1.8

—

(3005322) IgE [Units/volume] in Serum or Plasma

0.86

0.07

1.1

1.3

104.90

442.88

u/ml

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

237

1.06

0.06

2.6

1.8

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

139

1.09

0.05

3.1

—

(3009261) Glucose [Presence] in Urine by Test strip

756

1.03

0.04

7.1

3.9

0.00

estimate

—

107

(3007164) IgA [Mass/volume] in Serum or Plasma

299

1.04

0.04

1.3

2.44

2.48

g/l

0.05

152

(3012516) Albumin [Mass/volume] in Urine

468

1.03

0.04

4.0

3.2

1260.63

222.68

mg/l

0.47

310

(3020682) Albumin/Creatinine [Ratio] in Urine

498

1.03

0.04

4.8

4.0

29.38

10.31

mg/mmol

1.48

321

(3041096) Erythrocytes [Presence] in Urine by Automated

389

1.03

0.03

6.3

3.5

—

(3035350) Ketones [Presence] in Urine by Test strip

738

1.02

0.03

7.1

3.9

0.00

estimate

—

111

(3013139) Helicobacter pylori Ag [Presence] in Stool

1.09

0.03

1.1

1.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

186

1.02

0.00

17.7

8.1

—

(3000494) Fungus identified in Specimen by Culture

159

1.01

0.00

1.6

1.5

—

(3021601) Nitrite [Presence] in Urine by Test strip

744

0.99

0.00

9.8

5.4

0.00

estimate

—

109

(3048816) Calcium.ionized [Moles/volume] adjusted to pH 7.4 in Blood

113

0.97

0.00

20.0

3.2

1.23

1.22

mmol/l

0.43

(3022145) Colonoscopy Study observation

123

0.97

0.00

1.4

1.3

—

(586526) SARS-CoV-2 (COVID-19) RNA [Presence] in Nasopharynx by NAA with probe detection

107

1.03

0.00

2.1

1.4

—

(3019420) Tryptase [Mass/volume] in Serum or Plasma

0.00

0.0

2.0

—

6.26

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

0.0

2.3

—

712.00

—

(3049714) Procollagen type I.N-terminal propeptide [Mass/volume] in Serum

0.00

0.0

2.0

—

72.53

—

(3053028) Streptococcus sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3044936) Clostridioides difficile toxin A+B [Presence] in Stool by Immunoassay

0.00

0.0

1.3

—

(40768795) Lymph node Pathology biopsy report

0.00

0.0

1.0

—

(3035999) Lactate [Moles/volume] in Cerebral spinal fluid

0.00

0.0

1.3

—

1.71

—

(3045414) Leukocytes [Presence] in Urine

0.92

0.00

2.5

1.9

—

(3046896) Herpes virus 6 DNA [Presence] in Cerebral spinal fluid by NAA with probe detection

0.00

0.0

1.1

—

(3009550) Parvovirus B19 IgG Ab [Titer] in Serum

0.00

0.0

1.3

—

(3011831) Apolipoprotein B/Apolipoprotein A-I [Percentile]

0.00

0.0

1.5

—

(3031072) Herpes simplex virus 1 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3021513) Carbon dioxide [Partial pressure] in Mixed venous blood

0.00

0.0

5.2

—

(3022670) pH of Venous cord blood

0.00

0.0

1.0

—

(42529598) SUMO-activating enzyme subunit 1 Ab [Presence] in Serum by Line blot

0.00

0.0

1.4

—

(3045683) HLA typing for celiac disease panel - Blood or Tissue

0.00

0.0

1.0

—

(3013336) Amino acids [Identifier] in Serum or Plasma

0.00

0.0

1.2

—

(3020229) Cytomegalovirus DNA [Presence] in Specimen by NAA with probe detection

0.00

0.0

1.4

—

(3037556) Urate [Mass/volume] in Serum or Plasma

0.00

0.0

1.0

—

(42528593) TIF1-gamma Ab [Presence] in Serum by Line blot

0.00

0.0

1.4

—

(3044212) Herpes simplex virus 1+2 IgM Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.3

—

(3050898) Methicillin resistant Staphylococcus aureus [Presence] in Genital specimen by Organism specific culture

0.00

0.0

1.8

—

(3007695) Herpes simplex virus 2 IgG Ab [Presence] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3029075) Extractable nuclear Ab panel - Serum

0.00

0.0

1.0

—

(3013637) Mi-2 Ab [Presence] in Serum

0.00

0.0

1.4

—

(42868421) Varicella zoster virus IgM Ab [Presence] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.1

—

(3027901) Hemoglobin [Mass/volume] in Arterial cord blood

0.00

0.0

1.0

—

176.83

—

(3000285) Sodium [Moles/volume] in Blood

0.00

0.0

1.0

—

(3024666) Lithium, Blood [Moles/volume] in Serum or Plasma

0.00

0.0

5.8

—

0.60

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

0.0

1.0

—

(3022229) Phosphate [Moles/volume] in Urine

0.00

0.0

3.6

—

14.37

—

(3036071) Salmonella sp Ab [Titer] in Serum

0.00

0.0

1.3

—

(3001684) Respiratory syncytial virus Ag [Presence] in Specimen

0.00

0.0

1.0

—

(40761849) Varicella zoster virus IgG Ab [Units/volume] in Cerebral spinal fluid by Immunoassay

0.00

0.0

1.1

—

(3021125) Hepatitis C virus RNA [Presence] in Serum or Plasma by NAA with probe detection

0.00

0.0

1.0

—

(3033306) Mononuclear cells/100 leukocytes in Cerebral spinal fluid

0.00

0.0

1.2

—

(3037692) Legionella sp identified in Specimen by Organism specific culture

0.00

0.0

1.0

—

(3048929) Epstein Barr virus Ab [Presence] in Serum

0.92

0.00

2.2

1.9

—

(3030429) Borrelia sp DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.0

1.0

—

(3016628) Fibrinogen Ag [Mass/volume] in Platelet poor plasma by Immunoassay

0.00

0.0

1.2

—

0.48

—

(3000012) Reticulocyte production index

0.00

0.0

1.3

—

(3018921) Toxoplasma gondii IgA Ab [Units/volume] in Serum

0.00

0.0

1.0

—

(3002823) Mycoplasma pneumoniae IgG Ab [Units/volume] in Cerebral spinal fluid

0.00

0.0

1.0

—

(42529582) MDA5 Ab [Presence] in Serum by Line blot

0.00

0.0

1.4

—

(44813793)

0.00

0.0

1.1

—

(3022575) Varicella zoster virus IgG Ab [Units/volume] in Serum

0.00

0.0

1.0

—

1715.80

—

(44806420)

0.00

0.0

2.3

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.87

0.00

1.0

1.1

2.20

0.03

g/l

—

(3002670) Multiple inhalant allergen IgE Ab [Units/volume] in Serum

0.00

0.0

3.7

—

(36304052) Adalimumab Ab [Units/volume] in Serum or Plasma

0.00

0.0

2.6

—

(36306090) Helicobacter pylori [Presence] in Tissue by Organism specific culture

0.00

0.0

1.0

—

(3051101) Glucose [Moles/volume] in Cord blood

0.00

0.0

4.6

—

(3042299) inFLIXimab [Mass/volume] in Serum or Plasma

0.00

0.0

14.2

—

9.94

—

(43055089) Myosin Ab [Presence] in Serum or Plasma by Immunoblot

0.00

0.0

1.3

—

(3018006) Microscopic observation [Identifier] in Cervix by Cyto stain.thin prep

140

1.00

0.00

1.3

1.4

—

(3037677) Mycoplasma pneumoniae IgM Ab [Titer] in Cerebral spinal fluid

0.00

0.0

1.0

—

(3028433) Virus identified in Specimen by Culture

0.00

0.0

1.2

—

(3020717) Zinc [Moles/volume] in Serum or Plasma

0.00

0.0

2.0

—

12.27

—

(3006653) Thiamine [Moles/volume] in Blood

0.00

0.0

1.1

—

137.29

—

(3038071) Oxygen [Partial pressure] in Mixed venous blood

0.00

0.0

5.2

—

(40771527) Human papilloma virus E6+E7 mRNA [Presence] in Cervix by NAA with probe detection

0.00

0.0

1.8

—

Mortality – FinRegistry

↥

This endpoint is excluded (different definition than used in FinnGen).

Relationships between endpoints

↥

Index endpoint: C3_WILMS_TUMOR_EXALLC – Wilms' tumor, excluding all cancers (controls excluding all cancers)

GWS hits: -

This endpoint is excluded (different definition than used in FinnGen).

≡ Risteys

FG R12 + FR

FinnGen R11 + FinRegistry

FinnGen R10 + FinRegistry

FinnGen R10

FinnGen R9

FinnGen R8

FinnGen R7

FinnGen R6

FinnGen R5

FinnGen R4

FinnGen R3

Wilms' tumor, excluding all cancers (controls excluding all cancers)

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

All original rules

Similar endpoints

Case counts by codes

Upset plot

Case counts by code for Wilms' tumor, excluding all cancers (controls excluding all cancers) (C3_WILMS_TUMOR_EXALLC)

Summary Statistics

-FinRegistry-

-FinnGen-

Key figures

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

CodeWAS (R11)

LabWAS

Mortality – FinRegistry

Relationships between endpoints