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This is a non-core endpoint: only basic statistics are computed.

Exposure to noise

VWXY20_EXPOS_NOISE2

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 W42
  • Cause of death: ICD-10 W42

2 out of 7 registries used, show all original rules.

56

4. Check minimum number of events

None

56

5. Include endpoints

None

56

6. Filter based on genotype QC (FinnGen only)

49

Control definitions (FinnGen only)

Controls for this endpoint are individuals that are not cases.

Extra metadata

Level in the ICD hierarchy
5
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
W[2-4]

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 49 8 41
Unadjusted period prevalence (%) 0.02 0.00 0.02
Median age at first event (years) 65.76 43.42 70.12

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
51
Matched controls
510
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
W42
ICD-10 Finland
Exposure to noise
+∞
73.0
51
*
H83.3
ICD-10 Finland
Noise effects on inner ear
223.3
35.2
33
*
R5110
NOMESCO Finland
Evaluation of the need for aids, the testing, fitting and choice of the aid, instruction in use and delivery of it
14.7
21.7
29
42
R5140
NOMESCO Finland
Monitoring the use of the aid
11.3
17.1
26
43
R1100
NOMESCO Finland
General evaluation of the need for rehabilitation
82.7
15.9
17
*
Z01.1
ICD-10 Finland
Examination of ears and hearing
9.9
14.8
24
42
R5120
NOMESCO Finland
Preparation of an aid
24.3
14.1
20
13
H90.3
ICD-10 Finland
Sensorineural hearing loss, bilateral
7.2
11.4
27
69
Z03.9
ICD-10 Finland
Observation for suspected disease or condition, unspecified
7.4
11.1
23
51
R5130
NOMESCO Finland
Repair work or maintenance done on the aid
13.1
9.1
16
17
DFF30
NOMESCO Finland
Loudness discomfort Level (LDL)
21.8
8.6
12
7
DFF15
NOMESCO Finland
Speech audiometry
11.3
8.0
15
18
Z46.1
ICD-10 Finland
Fitting and adjustment of hearing aid
9.2
7.6
16
24
DFF00
NOMESCO Finland
Pure tone audiometry
5.6
7.0
17
42
FM1DE
NOMESCO Finland
Doppler ultrasound examination of heart
6.7
6.5
17
35

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
14
18
10.25
7.21
3.3
2.1
—
—
—
0
0
25
126
2.93
3.44
11.8
5.7
—
—
—
0
0
13
48
3.29
2.99
2.5
2.5
5.15
8.71
umol/l
0.77
13
40
10
40
2.86
2.02
3.1
2.3
—
0.00
estimate
—
0
9
19
108
2.21
1.83
3.9
2.8
—
—
estimate
—
0
0
7
25
3.08
1.72
2.7
7.2
26.89
25.00
mmol/l
—
7
25
7
26
2.95
1.65
2.4
4.2
25.43
23.49
mmol/l
—
7
26
0
44
0.00
1.60
0.0
4.7
—
7.34
—
0
28
0
41
0.00
1.38
0.0
1.2
—
—
—
0
0
9
48
2.06
1.07
2.2
4.9
3.00
1.11
mmol/l
—
9
38
16
104
1.78
1.00
2.9
2.7
4.83
3.59
e6/l
0.16
16
97
0
32
0.00
0.99
0.0
4.7
—
—
—
0
0
8
44
1.97
0.91
1.6
1.3
—
—
—
0
0
34
390
0.62
0.78
5.6
5.7
2.46
2.54
mmol/l
0.21
34
362
32
369
0.64
0.70
4.2
4.3
1.35
1.28
mmol/l
0.28
32
339
28
329
0.67
0.64
8.0
8.3
117.57
81.06
u/l
0.45
28
311
20
250
0.67
0.63
5.3
5.3
1.49
2.19
ug/l
1.15
20
223
0
19
0.00
0.61
0.0
1.2
—
—
—
0
0
8
54
1.57
0.61
5.3
3.2
4.18
4.73
e9/l
—
8
47
6
36
1.75
0.59
2.8
7.4
0.98
1.52
mmol/l
—
6
36
34
382
0.67
0.58
4.6
5.1
4.06
4.32
mmol/l
0.70
34
354
8
115
0.64
0.53
1.4
3.3
415.00
365.34
umol/l
—
8
98
38
416
0.66
0.52
26.2
23.2
88.82
88.04
umol/l
0.04
38
411
36
397
0.68
0.50
17.9
16.3
—
—
—
0
0
10
138
0.66
0.49
5.1
3.6
—
—
—
0
0
21
170
1.40
0.48
3.1
3.7
0.00
0.09
estimate
—
6
34
15
114
1.45
0.48
3.0
3.1
—
—
—
0
0
6
93
0.60
0.48
2.0
3.1
318.00
332.44
ng/l
—
6
73
26
221
1.36
0.43
3.8
3.6
0.00
0.00
estimate
—
6
42
0
15
0.00
0.42
0.0
1.1
—
—
—
0
0
0
15
0.00
0.42
0.0
1.1
—
—
—
0
0
0
15
0.00
0.42
0.0
21.5
—
—
—
0
0
0
16
0.00
0.42
0.0
1.3
—
—
—
0
0
0
17
0.00
0.41
0.0
1.1
—
—
—
0
0
17
136
1.38
0.41
2.7
3.4
2.31
2.33
mmol/l
0.25
17
123
0
18
0.00
0.40
0.0
2.8
—
294.00
—
0
5
12
90
1.44
0.40
1.3
1.3
—
—
—
0
0
5
36
1.43
0.39
1.0
1.5
—
—
—
0
0
26
225
1.32
0.37
3.8
3.6
0.00
0.00
estimate
—
6
45
22
186
1.32
0.37
4.8
6.3
1.19
1.20
mmol/l
0.35
22
165
26
226
1.31
0.35
3.9
3.7
0.00
0.00
estimate
—
6
42
10
75
1.41
0.33
2.5
2.7
24.00
23.93
%
—
10
69
34
369
0.76
0.31
4.8
5.6
5.94
6.08
mmol/l
0.36
34
342
11
86
1.36
0.29
2.7
2.7
14.80
13.39
umol/l
0.25
11
74
37
395
0.77
0.27
23.9
21.8
4.01
4.03
mmol/l
0.14
37
390
22
193
1.25
0.26
3.9
5.8
54.50
58.67
%
0.59
22
186
37
394
0.78
0.25
23.7
21.7
139.97
139.64
mmol/l
0.39
37
388
7
90
0.74
0.25
3.3
2.9
2.45
2.44
mmol/l
—
7
81
7
94
0.70
0.25
7.7
5.9
—
—
—
0
0
22
194
1.24
0.24
4.1
5.9
2.95
3.03
%
0.05
22
185
22
195
1.23
0.23
4.1
5.9
8.50
8.77
%
0.14
22
187
18
156
1.24
0.23
3.1
4.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.8
—
1.16
—
0
11
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.7
—
0.24
—
0
11
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
3.7
—
0.77
—
0
11
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.5
—
—
—
0
0
0
10
0.00
0.21
0.0
1.8
—
12.35
—
0
10
6
47
1.31
0.21
1.5
1.9
—
—
—
0
0
6
48
1.28
0.21
1.3
1.7
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.2
—
—
—
0
0
0
13
0.00
0.21
0.0
1.0
—
—
—
0
0
16
138
1.23
0.21
2.3
2.3
186.44
374.38
u/l
0.64
16
133
10
81
1.29
0.20
2.6
2.7
2.06
2.24
g/l
—
10
73
5
69
0.70
0.18
1.4
2.0
—
—
—
0
0
22
200
1.18
0.16
4.2
5.9
32.81
26.43
%
0.93
22
192
23
210
1.17
0.16
4.1
7.2
1.20
1.20
mmol/l
0.01
23
179
10
117
0.82
0.15
2.6
2.2
2.20
2.78
mg/l
—
10
103
17
188
0.86
0.14
1.8
2.2
92.53
93.96
pmol/l
—
8
107
24
256
0.88
0.11
4.4
5.2
6.38
6.78
mmol/l
0.41
24
241
17
185
0.88
0.10
1.8
2.7
—
—
estimate
—
0
0
21
195
1.13
0.10
4.2
5.9
0.78
0.64
%
0.65
21
186
13
144
0.87
0.10
4.2
4.6
—
—
—
0
0
6
57
1.06
0.09
1.3
1.6
—
—
—
0
0
23
216
1.12
0.09
5.4
5.7
0.04
0.04
e9/l
0.04
23
186
7
64
1.11
0.08
1.4
1.6
—
—
—
0
0
23
217
1.11
0.08
5.4
5.6
0.60
0.61
e9/l
0.05
23
189
15
138
1.12
0.07
1.7
1.8
16.53
20.91
nmol/l
0.70
15
114
10
89
1.15
0.07
2.5
3.3
561.00
581.06
mosm/kgh2o
—
10
79
22
232
0.91
0.06
4.8
6.6
12.32
12.87
umol/l
0.12
22
225
23
220
1.08
0.04
6.8
5.8
2.34
1.76
e9/l
0.57
23
197
23
220
1.08
0.04
5.5
6.1
0.20
0.22
e9/l
0.09
23
196
12
129
0.91
0.04
1.9
2.5
—
—
—
0
0
25
259
0.93
0.03
5.2
4.3
—
28.17
—
0
6
13
138
0.92
0.03
4.8
5.2
—
—
—
0
0
20
194
1.05
0.00
3.9
5.2
33.73
34.97
g/l
0.32
20
186
14
135
1.05
0.00
2.1
2.0
—
—
—
0
0
5
50
1.00
-0.00
2.0
7.9
2.14
0.44
mmol/l
—
5
38
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.4
—
—
—
0
0
5
55
0.90
-0.00
1.0
1.4
—
—
—
0
0
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
6
0.00
-0.00
0.0
5.8
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
92.40
—
0
5
6
63
0.95
-0.00
6.0
6.6
105.83
104.06
mmol/l
—
6
63
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
0.49
—
0
7
0
7
0.00
-0.00
0.0
1.3
—
58.77
—
0
7
0
8
0.00
-0.00
0.0
6.9
—
11.31
—
0
8
0
8
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.8
—
-2.58
—
0
5
0
6
0.00
-0.00
0.0
2.0
—
31.83
—
0
6
0
6
0.00
-0.00
0.0
1.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
276.00
—
0
5
0
5
0.00
-0.00
0.0
1.8
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.5
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.8
—
3.15
—
0
6

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: VWXY20_EXPOS_NOISE2 – Exposure to noise

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).