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This is a non-core endpoint: only basic statistics are computed.

Traumatic amputation of ankle and foot

ST19_TRAUMAT_AMPUT_ANKLE_FOOT

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

557745

1. Apply sex-specific rule

None

557745

2. Check conditions

None

557745

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 S98
  • Cause of death: ICD-10 S98

2 out of 7 registries used, show all original rules.

106

4. Check minimum number of events

None

106

5. Include endpoints

None

106

6. Filter based on genotype QC (FinnGen only)

93

Control definitions (FinnGen only)

Control exclude
ST19_INJURI_ANKLE_FOOT

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF4
Parent code in ICD-10
S90
Name in latin
Amputatio traumatica tarsi/pedis

Case counts by codes

FinnGen case counts by registry codes:

generic upset plot

Upset plot

Full data table

Summary Statistics

-FinRegistry-

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

-FinnGen-

Key figures

All Female Male
Number of individuals 93 24 69
Unadjusted period prevalence (%) 0.03 0.01 0.03
Median age at first event (years) 55.38 54.25 55.78

-FinnGen-

Age distribution of first events

-FinnGen-

Year distribution of first events

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

Matched cohort

Matched cases
96
Matched controls
960
Code
Vocabulary
Description
Odds Ratio
-log10(p)
N matched cases
N matched controls
S98.1
ICD-10 Finland
Traumatic amputation of one toe
+∞
61.1
52
*
S98.2
ICD-10 Finland
Traumatic amputation of two or more toes
+∞
33.3
30
*
NHQ40
NOMESCO Finland
Amputation of toe
56.1
26.9
31
8
QDB10
NOMESCO Finland
Major dressing of wound of skin of lower limb
18.3
16.7
26
19
QDB05
NOMESCO Finland
Revision of wound of skin of lower limb
22.4
16.7
24
14
QDG20
NOMESCO Finland
Operation for chronic ulcer or fistula of skin of lower limb
+∞
13.9
13
*
W31
ICD-10 Finland
Contact with other and unspecified machinery
19.0
13.3
20
13
SPAT1148
SPAT
Treatment of chronic ulcer or burn
6.1
13.1
28
61
T81.4
ICD-10 Finland
Infection following a procedure, not elsewhere classified
5.9
10.9
23
49
A46
ICD-10 Finland
Erysipelas
4.8
10.9
31
86
NHQ30
NOMESCO Finland
Amputation of foot, transmetatarsal
67.7
10.9
12
*
NH3AA
NOMESCO Finland
Foot and toes X-ray examination
9.9
10.9
22
28
L97
ICD-10 Finland
Ulcer of lower limb, not elsewhere classified
14.5
9.8
16
13
NHQ48
NOMESCO Finland
Revision of amputation of toe
+∞
9.5
9
*
SPAT1149
SPAT
Suture or treatment of traumatic wound
4.6
8.5
24
65
S92.5
ICD-10 Finland
Fracture of other toe
19.3
8.3
12
7
I70.2
ICD-10 Finland
Atherosclerosis of arteries of extremities
4.9
8.3
21
52
SPAT1229
SPAT
Assessment of need for aid
9.6
7.7
15
18
S98.3
ICD-10 Finland
Traumatic amputation of other parts of foot
+∞
7.4
7
*
S97
ICPC
Chronic ulcer skin
6.9
7.4
18
31
X59
ICD-10 Finland
Exposure to unspecified factor
3.7
7.4
30
106
SPAT1144
SPAT
Treatment of reopened or infected surgical wound
10.0
7.3
14
16
M86.9
ICD-10 Finland
Osteomyelitis, unspecified
24.5
6.8
9
*
L03.1
ICD-10 Finland
Cellulitis of other parts of limb
11.2
6.8
12
12
SPAT1253
SPAT
Initiation, adjustment, discontinuation or repetition of medication
3.2
6.7
39
171
S91.3
ICD-10 Finland
Open wound of other parts of foot
15.7
6.6
10
7
WX213
NOMESCO Finland
Lower leg blockade
74.6
6.5
7
*
J01FF01
ATC
clindamycin; systemic
3.1
6.4
36
154
TQW11
NOMESCO Finland
Vacuum treatment of wound
19.6
6.4
9
5
NGQ20
NOMESCO Finland
Amputation of lower leg
28.8
6.3
8
*
S98.4
ICD-10 Finland
Traumatic amputation of foot, level unspecified
+∞
6.3
6
*
GD1QA
NOMESCO Finland
Supine thorax X-ray examination
3.4
6.2
27
99
N03AX16
ATC
[U] pregabalin
3.2
6.1
30
118
L98.4
ICD-10 Finland
Chronic ulcer of skin, not elsewhere classified
16.3
6.0
9
6

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
26
89
3.63
6.63
3.3
1.8
—
—
—
0
0
50
300
2.39
4.24
3.7
3.2
7.39
8.48
mmol/l
0.95
41
261
26
120
2.60
3.83
3.9
1.8
—
—
—
0
0
46
290
2.13
3.23
4.6
3.9
13.66
11.77
mg/mmol
0.12
27
191
45
282
2.12
3.20
3.9
3.3
99.25
77.53
mg/l
0.22
28
193
5
9
5.79
2.24
1.0
1.1
—
—
—
0
0
39
272
1.73
1.79
6.7
2.3
—
—
—
0
0
29
194
1.71
1.51
2.5
2.5
—
—
—
0
0
33
235
1.62
1.34
6.9
4.8
—
—
—
0
0
18
109
1.80
1.30
1.4
1.3
—
—
—
0
0
10
49
2.16
1.27
3.2
4.0
383.40
168.15
ng/l
—
10
43
8
37
2.27
1.25
1.8
1.7
—
—
—
0
0
37
279
1.53
1.16
2.6
2.5
47.78
54.19
u/l
1.16
37
267
8
40
2.09
1.15
1.9
1.7
—
—
—
0
0
19
279
0.60
1.15
1.7
3.0
0.67
0.74
ug/l
—
7
179
13
74
1.88
1.13
1.9
2.2
9.38
12.82
ug/l
0.23
13
68
43
339
1.49
1.08
3.9
3.8
51.60
43.37
ng/l
0.11
35
243
5
22
2.34
1.04
2.2
2.6
61.68
57.15
%
—
5
22
28
206
1.51
0.96
3.7
3.5
1.02
1.02
kg/l
0.81
17
138
8
42
1.99
0.91
1.9
1.6
—
—
—
0
0
8
42
1.99
0.91
1.9
1.6
—
—
—
0
0
6
29
2.14
0.91
2.0
1.9
—
—
—
0
0
43
349
1.42
0.89
3.8
3.5
0.00
0.00
estimate
—
9
85
6
31
2.00
0.86
12.2
15.5
—
—
—
0
0
48
401
1.39
0.83
5.0
2.4
—
—
estimate
—
0
0
35
277
1.41
0.82
6.6
6.2
—
—
—
0
0
50
422
1.39
0.81
6.4
6.3
0.65
0.60
e9/l
0.92
45
358
0
24
0.00
0.80
0.0
1.2
—
—
—
0
0
5
25
2.05
0.74
2.4
2.5
22.04
24.01
mmol/l
—
5
25
41
339
1.37
0.73
1.8
2.0
83.62
95.67
pmol/l
0.87
15
165
7
43
1.68
0.68
1.7
1.6
—
—
—
0
0
18
131
1.46
0.65
2.4
1.7
—
—
—
0
0
23
291
0.72
0.62
1.7
2.1
—
—
—
0
0
5
30
1.70
0.62
1.2
1.4
—
—
—
0
0
0
21
0.00
0.61
0.0
1.2
—
567.67
—
0
21
15
107
1.48
0.60
2.3
1.8
—
—
—
0
0
9
61
1.52
0.56
4.9
2.5
7.39
7.43
ph
—
9
47
6
38
1.62
0.55
2.2
4.0
2.00
1.51
%
—
6
33
6
38
1.62
0.55
1.8
2.6
0.45
0.64
%
—
6
38
30
246
1.32
0.55
2.9
2.1
332.40
217.92
u/l
0.33
30
237
6
40
1.53
0.52
1.8
2.6
1.73
1.60
%
—
6
40
10
68
1.53
0.49
1.4
1.7
—
—
—
0
0
51
454
1.26
0.49
4.0
3.7
0.00
0.00
estimate
—
7
85
13
94
1.44
0.49
1.5
1.4
—
—
—
0
0
7
47
1.53
0.49
6.1
3.6
23.40
24.60
mmol/l
—
7
47
5
83
0.58
0.48
1.0
1.4
—
—
—
0
0
42
366
1.26
0.48
8.8
7.1
1.20
1.20
mmol/l
0.04
37
344
63
577
1.27
0.46
4.1
4.0
—
—
—
0
0
10
69
1.50
0.46
4.2
3.1
73.80
72.81
e9/l
—
10
54
31
262
1.27
0.45
3.7
3.1
0.00
0.00
estimate
—
9
79
40
451
0.81
0.43
4.3
5.2
1.91
1.90
ug/l
0.01
35
405
19
151
1.32
0.43
3.5
2.5
12.56
14.07
umol/l
0.46
19
143
0
15
0.00
0.41
0.0
1.6
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
2.91
—
0
11
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.1
—
—
—
0
0
0
16
0.00
0.41
0.0
1.2
—
—
—
0
0
5
34
1.50
0.41
4.2
2.1
—
—
—
0
0
5
36
1.41
0.39
1.4
1.1
—
—
—
0
0
31
267
1.24
0.38
5.1
3.7
—
—
—
0
0
6
45
1.36
0.34
1.0
1.2
—
—
—
0
0
6
45
1.36
0.34
5.3
2.5
—
—
—
0
0
49
447
1.20
0.33
4.2
3.7
0.00
0.00
estimate
—
9
93
7
52
1.37
0.32
2.7
3.2
—
—
—
0
0
7
52
1.37
0.32
1.6
2.8
—
—
—
0
0
12
94
1.32
0.30
2.9
3.0
2.21
1.87
%
0.36
12
88
21
178
1.23
0.29
1.1
1.3
0.96
1.73
u/ml
—
5
52
28
245
1.20
0.29
5.1
4.5
7.39
7.40
ph
0.42
23
165
10
77
1.33
0.27
6.5
12.4
—
—
—
0
0
5
72
0.68
0.27
1.4
1.3
—
—
—
0
0
29
324
0.85
0.25
5.6
3.7
80.76
81.36
e6/l
0.00
23
235
82
792
1.24
0.25
27.1
15.6
23.92
25.35
mg/l
0.18
73
661
39
356
1.16
0.25
3.1
3.2
6.23
6.05
ph
0.57
26
219
15
125
1.24
0.24
4.1
9.4
105.33
103.93
mmol/l
0.32
15
125
19
163
1.21
0.24
2.1
1.9
453.74
443.30
pmol/l
0.05
19
145
7
93
0.73
0.23
1.1
1.3
—
—
—
0
0
5
39
1.30
0.23
1.4
1.2
5.41
6.45
u/l
—
5
29
8
101
0.77
0.22
1.4
1.5
—
—
—
0
0
0
11
0.00
0.21
0.0
1.2
—
—
—
0
0
0
11
0.00
0.21
0.0
1.1
—
—
—
0
0
0
11
0.00
0.21
0.0
1.4
—
—
—
0
0
0
13
0.00
0.21
0.0
1.3
—
—
—
0
0
0
13
0.00
0.21
0.0
1.5
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
—
—
0
0
0
14
0.00
0.20
0.0
1.1
—
10.56
—
0
7
39
361
1.14
0.20
13.5
12.5
0.00
0.00
e9/l
0.50
32
292
11
91
1.24
0.18
1.3
1.5
—
—
—
0
0
47
443
1.12
0.17
4.1
3.6
0.00
0.00
estimate
—
9
97
18
159
1.16
0.16
1.2
1.4
3.34
2.53
g/l
—
8
103
79
770
1.15
0.14
5.5
5.0
6.27
6.01
mmol/l
0.96
73
719
27
250
1.11
0.13
2.3
2.7
—
0.20
—
0
10
33
350
0.91
0.11
3.0
3.1
—
—
—
0
0
25
267
0.91
0.10
5.2
6.3
—
—
—
0
0
6
57
1.06
0.08
2.3
4.2
—
—
—
0
0
17
156
1.11
0.08
2.8
1.9
—
—
—
0
0
7
63
1.12
0.08
7.9
9.0
24.26
24.53
mmol/l
—
7
63
7
65
1.08
0.08
4.0
13.4
94.74
93.66
%
—
7
65
7
67
1.05
0.08
1.1
1.3
—
—
—
0
0
18
194
0.91
0.08
11.0
5.4
—
—
—
0
0
6
74
0.80
0.08
2.0
1.6
—
—
—
0
0
87
875
0.94
0.07
38.1
23.7
252.43
240.99
e9/l
0.83
87
860
87
875
0.94
0.07
37.9
23.6
30.39
30.45
pg
0.12
87
869
87
875
0.94
0.07
38.0
24.4
40.47
41.15
%
0.61
87
868
87
875
0.94
0.07
38.6
23.8
133.93
138.71
g/l
1.63
87
868
87
874
0.95
0.07
38.0
23.7
91.61
91.06
fl
0.56
87
868
84
828
1.12
0.07
23.9
14.1
—
—
—
0
0
9
101
0.88
0.06
1.1
1.4
—
—
—
0
0
12
112
1.08
0.03
3.9
9.4
7.34
7.42
ph
—
7
63
82
818
1.02
0.00
30.0
18.3
139.11
139.69
mmol/l
1.29
82
807
24
242
0.99
0.00
1.3
1.4
—
—
—
0
0
29
289
1.00
0.00
4.9
3.1
17.42
269.50
e6/l
0.59
24
222
17
175
0.97
0.00
5.3
2.8
476.50
562.24
mosm/kgh2o
0.90
12
153
24
239
1.01
0.00
5.2
2.9
0.21
0.47
e6/l
1.17
19
171
25
249
1.01
0.00
5.0
3.7
0.00
0.00
estimate
—
9
84
6
64
0.93
0.00
3.0
4.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
2.1
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.4
—
—
—
0
0
0
9
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.4
—
—
—
0
0
0
7
0.00
-0.00
0.0
6.4
—
—
—
0
0
0
5
0.00
-0.00
0.0
3.4
—
1328.00
—
0
5
82
820
1.00
-0.00
30.3
18.4
4.08
4.00
mmol/l
2.40
82
805
0
7
0.00
-0.00
0.0
1.1
—
275.71
—
0
7
0
8
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
8
0.00
-0.00
0.0
3.3
—
101.19
—
0
8
0
9
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
6
0.00
-0.00
0.0
2.0
—
9.07
—
0
6
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
15
150
1.00
-0.00
3.7
3.2
0.80
0.82
mmol/l
0.20
15
138
0
8
0.00
-0.00
0.0
2.8
—
4.19
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
1667.80
—
0
5
0
8
0.00
-0.00
0.0
2.8
—
1.17
—
0
8
0
5
0.00
-0.00
0.0
1.2
—
10.50
—
0
5
0
8
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
9.2
—
0.58
—
0
6
0
8
0.00
-0.00
0.0
2.8
—
106.50
—
0
8
0
5
0.00
-0.00
0.0
1.4
—
113.00
—
0
5
0
5
0.00
-0.00
0.0
4.6
—
52.00
—
0
5
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.2
—
28.20
—
0
5
0
5
0.00
-0.00
0.0
1.2
—
—
—
0
0
0
9
0.00
-0.00
0.0
2.3
—
—
—
0
0
0
5
0.00
-0.00
0.0
1.0
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
285.29
—
0
7

Mortality – FinRegistry

This endpoint is excluded from FinRegistry analyses (omitted endpoint).

Relationships between endpoints

Index endpoint: ST19_TRAUMAT_AMPUT_ANKLE_FOOT – Traumatic amputation of ankle and foot

GWS hits: -

This endpoint is excluded from FinRegistry analyses (omitted endpoint).