Psoriatic arthropathies, strict definition

M13_PSORIARTH_STRICT

No definition available.

Endpoint definition

↥

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps	FinnGen
Phenotype data	557745
1. Apply sex-specific rule None	557745
2. Check conditions M13_PSORIARTH_ICD10	4871
3. Check pre-conditions, main-only, mode, registry filters Registry filters: KELA reimbursements: KELA codes — ANY KELA reimbursements: ICD-10 — M07.1, M07.1L40.5, M07.2, M07.2L40.5, M07.3, M07.3L40.5 1 out of 7 registries used, show all original rules.	34
4. Check minimum number of events None	34
5. Include endpoints None	34
6. Filter based on genotype QC (FinnGen only)	31

Control definitions (FinnGen only)

Control conditions: not M13_PSORIARTH_ICD10

Extra metadata

Level in the ICD hierarchy: C
First used in FinnGen datafreeze: DF3

NAME	M13_PSORIARTH_STRICT
CONTROL_EXCLUDE
CONTROL_PRECONDITIONS
CONTROL_CONDITIONS	!M13_PSORIARTH_ICD10
SEX
INCLUDE
PRE_CONDITIONS
CONDITIONS	M13_PSORIARTH_ICD10
OUTPAT_ICD
OUTPAT_OPER
HD_MAINONLY
HD_ICD_10_ATC
HD_ICD_10
HD_ICD_9
HD_ICD_8
HD_ICD_10_EXCL
HD_ICD_9_EXCL
HD_ICD_8_EXCL
COD_MAINONLY
COD_ICD_10
COD_ICD_9
COD_ICD_8
COD_ICD_10_EXCL
COD_ICD_9_EXCL
COD_ICD_8_EXCL
OPER_NOM
OPER_HL
OPER_HP1
OPER_HP2
KELA_REIMB	ANY
KELA_REIMB_ICD	M07&L405\|M07[1-3]
KELA_ATC_NEEDOTHER
KELA_ATC
KELA_VNRO_NEEDOTHER
KELA_VNRO
CANC_TOPO
CANC_TOPO_EXCL
CANC_MORPH
CANC_MORPH_EXCL
CANC_BEHAV

Similar endpoints

↥

List of similar endpoints to Psoriatic arthropathies, strict definition based on the number of shared cases.

Similar with more cases:

Similar with less cases:

None

Case counts by codes

↥

FinnGen case counts by registry codes:

Not enough data for upset plot.

Full data table

Summary Statistics

↥

-FinRegistry-

Key figures

	All	Female	Male
Number of individuals
Whole population	-	-	-
Only index persons	-	-	-
Unadjusted period prevalence (%)
Whole population	-	-	-
Only index persons	-	-	-
Median age at first event (years)
Whole population	-	-	-
Only index persons	-	-	-

-FinnGen-

Key figures

	All	Female	Male
Number of individuals	31	15	16
Unadjusted period prevalence (%)	0.01	0.01	0.01
Median age at first event (years)	48.99	47.96	49.96

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS

↥

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log₁₀(p-value) ≥ 6.

No data available

LabWAS

↥

N Cases

N Controls

-log₁₀(p)

cases

controls

cases

controls

unit

-log₁₀(p)

N cases

N controls

(3026493) Urate [Moles/volume] in Serum or Plasma

11.97

9.17

3.9

326.76

343.73

umol/l

0.35

(3041942) Cyclic citrullinated peptide Ab [Units/volume] in Serum

7.20

7.24

1.4

1.2

1.52

3.43

u/ml

—

(3013707) Erythrocyte sedimentation rate [Velocity] in Red Blood Cells by Westergren method

208

+∞

5.45

8.8

4.2

13.56

8.66

mm/h

1.58

199

(3015736) pH of Urine

124

4.72

3.96

3.7

3.2

5.79

6.22

1.42

(3008898) HLA-B27 [Presence]

7.78

3.77

1.0

1.1

—

(3002030) Lymphocytes/Leukocytes in Blood

151

4.83

3.53

10.7

6.9

29.01

28.47

0.13

145

(3018010) Neutrophils/Leukocytes in Blood

151

4.83

3.53

10.9

6.8

57.45

57.67

0.05

146

(3029937) Albumin [Presence] in Urine by Test strip

3.92

3.50

6.2

3.6

0.00

estimate

—

(3022096) Basophils/Leukocytes in Blood

145

4.29

3.21

11.0

7.0

0.78

0.80

0.07

133

(3006504) Eosinophils/Leukocytes in Blood

146

3.56

2.81

11.5

7.0

3.28

2.76

0.49

139

(40760892) CBC W Ordered Manual Differential panel - Blood

3.34

2.77

7.2

5.7

—

(3019069) Monocytes/Leukocytes in Blood

147

3.52

2.60

11.5

7.1

7.81

8.56

0.71

140

(3000494) Fungus identified in Specimen by Culture

3.45

2.46

1.7

1.4

—

(3023420) DNA double strand Ab [Units/volume] in Serum

5.40

2.39

1.3

2.1

—

5.08

—

(3013527) Hepatitis B virus core IgM Ab [Presence] in Serum

6.34

2.30

1.4

1.2

—

(40763086) Leukocyte esterase [Presence] in Urine by Automated test strip

116

2.93

2.18

5.5

3.2

0.00

estimate

—

(3030981) Hyaline casts [#/volume] in Urine by Automated count

3.33

1.95

2.3

2.1

0.00

0.14

e6/l

—

(3021879) Hepatitis B virus core Ab [Presence] in Serum

3.07

1.93

1.8

1.7

—

(3017143) Hepatitis C virus Ab [Presence] in Serum

2.77

1.83

1.7

1.8

—

(3019284) Hepatitis B virus surface Ag [Presence] in Serum

2.63

1.74

1.8

1.7

—

(3011397) Hemoglobin [Presence] in Urine by Test strip

2.49

1.57

4.8

3.8

—

(3015399) Transferrin receptor.soluble [Mass/volume] in Serum or Plasma

2.50

1.52

3.3

1.7

2.77

2.82

mg/l

0.03

(43054903) Holo-transcobalamin II [Moles/volume] in Serum

109

2.19

1.29

1.6

1.9

86.21

93.39

pmol/l

—

(40761536) Microorganisms panel - Urine sediment

2.92

1.26

6.0

2.5

—

(3003396) Base excess in Arterial blood by calculation

0.00

1.24

0.0

9.4

—

-0.11

—

(3019977) pH of Arterial blood

0.00

1.23

0.0

8.8

—

7.41

—

(3023024) Carbon dioxide [Partial pressure] in Capillary blood

2.63

1.13

3.4

2.3

5.56

5.07

kpa

—

(42870588) Differential panel, method unspecified - Blood

2.06

1.10

10.8

6.9

—

(3020564) Creatinine [Moles/volume] in Serum or Plasma

296

+∞

0.83

22.8

18.2

85.53

76.40

umol/l

0.26

291

(3014111) Lactate [Moles/volume] in Serum or Plasma

2.28

0.78

1.0

10.6

1.76

1.43

mmol/l

—

(3042936) Bacteria identified in Isolate by Culture

1.96

0.77

1.9

2.1

—

(3019902) Methicillin resistant Staphylococcus aureus [Presence] in Specimen by Organism specific culture

2.18

0.76

3.6

3.0

—

(46235355) HIV 1 and 2 tests - Meaningful Use set

1.84

0.74

2.0

2.2

—

(3045783) Sodium and Potassium panel [Moles/volume] - Serum or Plasma

1.93

0.69

2.6

7.7

—

(3013826) Glucose [Moles/volume] in Serum or Plasma

167

1.75

0.69

2.4

5.7

6.23

6.34

mmol/l

0.10

152

(3014218) Bicarbonate [Moles/volume] standard in Arterial blood

0.00

0.63

0.0

10.8

—

24.00

—

(3020630) Protein [Mass/volume] in Serum or Plasma

0.00

0.62

0.0

7.7

—

66.32

—

(3014007) Fractional oxyhemoglobin in Arterial blood

0.00

0.62

0.0

13.3

—

92.46

—

(40761511) CBC panel - Blood by Automated count

298

+∞

0.62

14.2

11.9

—

(40758558) Short blood count panel - Blood

102

1.66

0.61

5.6

7.1

—

(40768797) Stomach Pathology biopsy report

1.82

0.61

1.8

1.3

—

(3003510) Neisseria gonorrhoeae DNA [Presence] in Urine by NAA with probe detection

1.75

0.54

1.7

2.6

—

(3041096) Erythrocytes [Presence] in Urine by Automated

1.61

0.52

5.8

2.4

0.00

estimate

—

(3024950) Chlamydia trachomatis DNA [Presence] in Urine by NAA with probe detection

1.55

0.50

1.7

2.9

—

(3044889) 12 lead EKG panel

197

1.59

0.47

3.7

3.2

—

(3019060) Gas panel - Arterial blood

0.00

0.42

0.0

6.1

—

(1001926) Buprenorphine [Presence] in Urine by Screen method

0.00

0.42

0.0

1.3

—

(36032419) SARS-CoV-2 (COVID-19) Ag [Presence] in Upper respiratory specimen by Immunoassay

0.00

0.42

0.0

1.9

—

(3004588) Protein electrophoresis panel - Serum or Plasma

0.00

0.42

0.0

5.8

—

(3001079) Blood group antibody screen [Presence] in Serum or Plasma

110

1.48

0.41

2.1

3.2

—

estimate

—

(3001122) Ferritin [Mass/volume] in Serum or Plasma

142

1.42

0.35

5.4

2.9

185.06

124.92

ug/l

0.45

136

(3029187) Natriuretic peptide.B prohormone N-Terminal [Mass/volume] in Serum or Plasma

1.33

0.31

1.8

3.8

2303.38

860.65

ng/l

—

(3023368) Bacteria identified in Blood by Culture

1.31

0.30

3.4

4.2

—

(3024135) Streptococcus.beta-hemolytic [Presence] in Throat by Organism specific culture

0.67

0.28

2.2

1.8

—

(3015377) Calcium [Moles/volume] in Serum or Plasma

0.72

0.27

1.4

4.1

2.35

2.34

mmol/l

—

(40768804) Tissue Pathology biopsy report

108

1.34

0.25

1.6

1.8

—

(3002256) Pathology report gross observation

1.41

0.25

1.0

1.2

—

(3012477) Bordetella pertussis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.22

0.0

2.0

—

(3002482) Mycoplasma pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

0.22

0.0

2.0

—

(3042194) Human metapneumovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

0.22

0.0

2.2

—

(3010813) Leukocytes [#/volume] in Blood

310

+∞

0.22

29.1

22.7

7.22

6.56

e9/l

1.19

305

(3026361) Erythrocytes [#/volume] in Blood

310

+∞

0.22

29.0

22.4

4.68

4.60

e12/l

0.40

304

(3027545) Mycoplasma pneumoniae Ab [Presence] in Serum by Immunoassay

0.00

0.22

0.0

1.4

—

(4094501) Cardiovascular stress test using bicycle ergometer

0.00

0.22

0.0

1.0

—

(3014162) Mycobacterium tuberculosis DNA [Presence] in Specimen by NAA with probe detection

0.00

0.22

0.0

3.2

—

(3040853) Adenovirus DNA [Identifier] in Specimen by NAA with probe detection

0.00

0.21

0.0

2.2

—

(3050129) First trimester maternal screen panel - Serum or Plasma

0.00

0.21

0.0

1.3

—

(21494755) Public health laboratory ask at order entry panel

1.25

0.21

1.3

1.4

—

(3011288) Drugs identified in Urine by Screen method Nominal

0.00

0.21

0.0

1.3

—

(3028707) Methadone [Presence] in Urine by Screen method

0.00

0.21

0.0

1.2

—

(3009445) Proteinase 3 Ab [Units/volume] in Serum

0.00

0.21

0.0

1.1

—

(3039443) Prostate specific Ag panel - Serum or Plasma

0.00

0.20

0.0

1.4

—

(3026008) Bacteria identified in Urine by Culture

1.21

0.19

2.9

2.8

—

(1761868) Lipid panel - Serum or Plasma

145

1.21

0.13

4.0

2.6

—

(3016771) Amylase [Enzymatic activity/volume] in Serum or Plasma

1.20

0.11

2.5

55.27

56.23

u/l

0.06

(3003694) ABO and Rh group [Type] in Blood

0.83

0.08

1.9

1.4

—

(3021347) Calcium.ionized [Moles/volume] in Serum or Plasma

119

1.16

0.07

4.0

8.2

1.21

mmol/l

0.05

111

(706163) SARS-CoV-2 (COVID-19) RNA [Presence] in Respiratory system specimen by NAA with probe detection

207

1.04

0.00

4.1

3.6

—

(46236098) ABO and Rh group [Type] in Blood by Confirmatory method

0.84

0.00

1.4

3.1

—

(3013512) EKG study

1.05

0.00

3.6

3.1

—

(3016650) Hepatitis A virus Ab [Presence] in Serum

0.00

-0.00

0.0

1.1

—

(3038515) Glucose [Moles/volume] in Venous blood

0.00

-0.00

0.0

3.3

—

6.27

—

(3047007) Chlamydophila sp Ab [Presence] in Serum

0.00

-0.00

0.0

1.0

—

(3043747) Beta 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

5.8

—

3.74

—

(3042206) Streptococcus agalactiae Ag [Presence] in Vaginal fluid

0.00

-0.00

0.0

1.1

—

(3008909) Norovirus RNA [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

1.6

—

(3002148) Methylenedioxymethamphetamine [Presence] in Urine by Screen method

0.00

-0.00

0.0

1.0

—

(3025468) Yersinia sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

2.8

—

(3009340) Metanephrine [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

2.3

—

(3001334) Neutrophil cytoplasmic Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.1

—

(3004383) Neutrophil cytoplasmic Ab.classic [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.2

—

(3005988) Vibrio sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

2.8

—

(3007847) Interleukin 2 Receptor Soluble [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

1.4

—

960.40

—

(3047169) Lambda light chains.free [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

6.6

—

19.64

—

(3020321) Streptococcus agalactiae [Presence] in Vaginal fluid by Organism specific culture

0.00

-0.00

0.0

1.5

—

(21494670) JAK2 gene exon 14 targeted mutation analysis in Blood or Tissue by Molecular genetics method

0.00

-0.00

0.0

1.0

—

(40768793) Breast Pathology biopsy report

0.00

-0.00

0.0

1.2

—

(44790048) Parainfluenza type 2 nucleic acid detection

0.00

-0.00

0.0

1.7

—

(3005702) Mycobacterium sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

2.2

—

(3005715) Vancomycin [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

6.3

—

12.88

—

(3048821) Cortisol [Moles/volume] in Serum or Plasma --post 1 mg dexamethasone PO overnight

0.00

-0.00

0.0

1.0

—

(3029713) Protein.monoclonal band 1 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

6.4

—

0.00

—

(3025023) Rhinovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.6

—

(3029511) Human papilloma virus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.1

—

(3031478) Chlamydophila pneumoniae DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.2

—

(3003284) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum by Immunofluorescence

0.00

-0.00

0.0

1.2

—

(3045142) Bone marrow Pathology biopsy report

0.00

-0.00

0.0

1.4

—

(3049804) Myeloperoxidase IgG Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.2

—

(21493466) Plesiomonas shigelloides DNA [Presence] in Stool by NAA with non-probe detection

0.00

-0.00

0.0

2.8

—

(42529201) Cancer Ag 19-9 [Units/volume] in Serum or Plasma by Immunoassay

0.00

-0.00

0.0

2.8

—

9.27

—

(3049207) Fetal Trisomy 21 risk [Likelihood] Based on maternal age

0.00

-0.00

0.0

1.4

—

(3015322) Alpha 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

6.4

—

3.31

—

(3000093) Morphology [Interpretation] in Blood Narrative

0.00

-0.00

0.0

1.0

—

(3029634) Reagin Ab [Titer] in Serum by VDRL

0.00

-0.00

0.0

2.6

—

(21492888) Glucose tolerance 2 hours gestational panel - Serum or Plasma

0.00

-0.00

0.0

2.4

—

(3016881) Enterovirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.6

—

(1002102) Choriogonadotropin.intact+Beta subunit [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

1.3

—

43.44

—

(3044640) Blood type and Crossmatch panel - Blood

0.91

-0.00

1.3

2.6

—

(3019539) Treponema pallidum Ab [Titer] in Serum by Hemagglutination

0.00

-0.00

0.0

2.6

—

(3035797) Protein.monoclonal band 2 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

6.4

—

0.00

—

(1761482) Bacteria [#/volume] in Urine by Culture

0.00

-0.00

0.0

4.0

—

(3043238) Trisomy 21 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.6

—

(3042596) Human coronavirus RNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

1.4

—

(3035637) Corticotropin [Mass/volume] in Plasma

0.00

-0.00

0.0

1.0

—

18.00

—

(3043453) Neutrophil cytoplasmic Ab.perinuclear [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3043723) Beta 1 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

5.8

—

4.44

—

(3037756) Immunofixation for Serum or Plasma

0.00

-0.00

0.0

1.7

—

(3034860) Kappa light chains.free [Mass/volume] in Serum

0.00

-0.00

0.0

6.6

—

35.46

—

(3023183) Ammonium ion [Moles/volume] in Plasma

0.00

-0.00

0.0

3.3

—

53.88

—

(3023150) Myeloperoxidase Ab [Units/volume] in Serum

0.00

-0.00

0.0

1.0

—

(44790049) Parainfluenza type 3 nucleic acid detection

0.00

-0.00

0.0

1.7

—

(40765161) Human bocavirus DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.3

—

(3024561) Albumin [Mass/volume] in Serum or Plasma

120

1.00

-0.00

4.1

5.0

37.97

36.80

g/l

0.40

115

(3020565) Legionella pneumophila DNA [Presence] in Specimen by NAA with probe detection

0.00

-0.00

0.0

2.0

—

(40760888) Immunoglobulin light chains.free panel - Serum

0.00

-0.00

0.0

7.3

—

(3012568) Campylobacter sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

2.8

—

(3046294) Neutrophil cytoplasmic Ab.classic [Titer] in Serum

0.00

-0.00

0.0

1.0

—

(3050380) Cytology report of Cervical or vaginal smear or scraping Cyto stain

0.00

-0.00

0.0

1.3

—

(3009466) Valproate [Moles/volume] in Serum or Plasma

0.00

-0.00

0.0

4.0

—

199.33

—

(3024522) Salmonella sp identified in Specimen by Organism specific culture

0.00

-0.00

0.0

2.8

—

(3006588) Cancer Ag 15-3 [Units/volume] in Serum or Plasma

0.00

-0.00

0.0

5.2

—

20.33

—

(3025130) Human papilloma virus identified in Specimen

0.00

-0.00

0.0

1.5

—

(3047352) Trisomy 18 risk [Likelihood] in Fetus

0.00

-0.00

0.0

1.4

—

(44806118) Parainfluenza type 4 nucleic acid detection

0.00

-0.00

0.0

1.7

—

(3011985) Renin [Units/volume] in Plasma

0.00

-0.00

0.0

1.0

—

19.43

—

(42868716) Shigella species+EIEC invasion plasmid antigen H ipaH gene [Presence] in Stool by NAA with probe detection

0.00

-0.00

0.0

2.8

—

(21494815) CD4 cells/Lymphocytes in Specimen

0.00

-0.00

0.0

2.0

—

34.54

—

(3043109) Cytology report of Tissue fine needle aspirate Cyto stain

0.00

-0.00

0.0

1.0

—

(3029379) Protein.monoclonal band 4 [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

6.4

—

0.00

—

(44790047) Parainfluenza type 1 nucleic acid detection

0.00

-0.00

0.0

1.7

—

(3005229) Alpha 2 globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

5.8

—

7.15

—

(3023465) Gamma globulin [Mass/volume] in Serum or Plasma by Electrophoresis

0.00

-0.00

0.0

5.8

—

11.07

—

(3011960) Natriuretic peptide B [Mass/volume] in Serum or Plasma

0.00

-0.00

0.0

2.3

—

35.43

—

(21494434) Karyotype in Bone marrow

0.00

-0.00

0.0

1.0

—

Mortality – FinRegistry

↥

Association

Association between endpoint M13_PSORIARTH_STRICT and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have M13_PSORIARTH_STRICT.

N-year risk	Females	Males
1	No data	No data
5	No data	No data
10	No data	No data
15	No data	No data
20	No data	No data

Relationships between endpoints

↥

Index endpoint: M13_PSORIARTH_STRICT – Psoriatic arthropathies, strict definition

GWS hits: -

Endpoint

Case Overlap

Survival Analysis

Genetic Correlations

Genetic Signals

N (Jaccard index)

HR [CI]

rg [CI]

Hits

Coloc Hits

FinRegistry

FinnGen

FinRegistry

FinnGen

Loading data

Psoriatic arthropathies, strict definition

Endpoint definition

Endpoint definition steps

FinnGen

Phenotype data

1. Apply sex-specific rule

2. Check conditions

3. Check pre-conditions, main-only, mode, registry filters

4. Check minimum number of events

5. Include endpoints

6. Filter based on genotype QC (FinnGen only)

Similar endpoints

Case counts by codes

Summary Statistics

-FinRegistry-

Key figures

-FinnGen-

Key figures

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

-FinnGen-

Cumulative Incidence Function

CodeWAS

LabWAS

Mortality – FinRegistry

Association

Females

Males

Mortality risk

Relationships between endpoints