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This is a non-core endpoint: only basic statistics are computed.

Other disorders of middle ear and mastoid in diseases classified elsewhere

H8_MIDDMASTINOTH

Endpoint definition

Report an error or suggest an improvement for this endpoint codes

Endpoint definition steps

FinnGen

Phenotype data

519972

1. Apply sex-specific rule

None

519972

2. Check conditions

None

519972

3. Check pre-conditions, main-only, mode, registry filters

Registry filters:

  • Hospital discharge: ICD-10 H75*
  • Cause of death: ICD-10 H75*

2 out of 7 registries used, show all original rules.

5

4. Check minimum number of events

None

5

5. Include endpoints

None

5

6. Filter based on genotype QC (FinnGen only)

None

0

Control definitions (FinnGen only)

Control exclude
H8_MIDDLEMASTOID

Extra metadata

Level in the ICD hierarchy
3
First used in FinnGen datafreeze
DF2

Case counts by codes

FinnGen case counts by registry codes:

No upset plot: unknown.

No upset table: unknown.

Summary Statistics

-FinRegistry-

Key figures

All Female Male
Number of individuals
Whole population 38 18 19
Only index persons 34 17 17
Unadjusted period prevalence (%)
Whole population 0.00 0.00 0.00
Only index persons 0.00 0.00 0.00
Median age at first event (years)
Whole population 52.92 58.13 47.55
Only index persons 59.13 59.59 58.67

-FinnGen-

Key figures

All Female Male
Number of individuals - - -
Unadjusted period prevalence (%) - - -
Median age at first event (years) - - -

-FinRegistry-

Age distribution of first events

-FinnGen-

Age distribution of first events

-FinRegistry-

Year distribution of first events

-FinnGen-

Year distribution of first events

-FinRegistry-

Cumulative Incidence Function

No data

-FinnGen-

Cumulative Incidence Function

Not a core endpoint, no data to show.

CodeWAS (R11)

CodeWAS is a tool for exploring the associations between an endpoint and all of the medical codes and drug codes.

This is a new tool, please reach out using the contact form for feedback and improvement ideas.

First, a cohort is built by matching controls to the endpoint cases using year of birth and sex. Then, a Fisher test is done for all the medical codes and drug codes between the cases and controls of this cohort. Codes are reported in the table below if they have −log10(p-value) ≥ 6.

No data available

LabWAS

OMOP Concept
People with measurements
Mean N measurements
Mean measured value
(ID) Name
N Cases
N Controls
OR
-log10(p)
cases
controls
cases
controls
unit
-log10(p)
N cases
N controls
5
35
+∞
0.51
3.2
3.5
5.28
5.43
mmol/l
—
5
35
5
39
+∞
0.24
8.4
10.3
—
—
—
0
0
5
39
+∞
0.24
3.2
4.2
4.40
4.59
mmol/l
—
5
39
0
12
0.00
0.24
0.0
2.8
—
0.00
—
0
6
0
9
0.00
0.24
0.0
1.3
—
—
—
0
0
5
43
+∞
0.00
16.2
14.4
30.20
30.35
pg
—
5
43
5
43
+∞
0.00
16.4
14.5
230.20
246.19
e9/l
—
5
43
5
43
+∞
0.00
16.2
14.5
4.60
4.59
e12/l
—
5
43
5
43
+∞
0.00
16.2
14.7
5.84
6.18
e9/l
—
5
43
5
43
+∞
0.00
16.2
14.6
139.20
139.19
g/l
—
5
43
5
43
+∞
0.00
16.2
14.4
89.60
90.02
fl
—
5
43
0
6
0.00
-0.00
0.0
3.2
—
3.27
—
0
6
0
6
0.00
-0.00
0.0
2.0
—
—
—
0
0
0
5
0.00
-0.00
0.0
2.2
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.1
—
—
—
0
0
0
5
0.00
-0.00
0.0
4.0
—
—
—
0
0
0
6
0.00
-0.00
0.0
1.3
—
—
—
0
0
0
7
0.00
-0.00
0.0
1.3
—
—
—
0
0

Mortality – FinRegistry

Association

Association between endpoint H8_MIDDMASTINOTH and mortality.

Females

No data

Males

No data

Mortality risk

Mortality risk for people of age

years, who have H8_MIDDMASTINOTH.

N-year risk Females Males
1 No data No data
5 No data No data
10 No data No data
15 No data No data
20 No data No data

Relationships between endpoints

Index endpoint: H8_MIDDMASTINOTH – Other disorders of middle ear and mastoid in diseases classified elsewhere

GWS hits: -

Endpoint
Case Overlap
Survival Analysis
Genetic Correlations
Genetic Signals
N (Jaccard index)
HR [CI]
rg [CI]
Hits
Coloc Hits
FinRegistry
FinnGen
FinRegistry
FinnGen
FinnGen
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